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BG108272A - Арилсулфонамиди като противовирусни средства - Google Patents

Арилсулфонамиди като противовирусни средства Download PDF

Info

Publication number
BG108272A
BG108272A BG108272A BG10827203A BG108272A BG 108272 A BG108272 A BG 108272A BG 108272 A BG108272 A BG 108272A BG 10827203 A BG10827203 A BG 10827203A BG 108272 A BG108272 A BG 108272A
Authority
BG
Bulgaria
Prior art keywords
hydroxy
amino
alkyl
halogen
general formula
Prior art date
Application number
BG108272A
Other languages
Bulgarian (bg)
English (en)
Inventor
Tobias Wunberg
Wolfgang Bender
Peter Eckenberg
Sabine Hallenberger
Kerstin Henninger
Joerg Keldenich
Armin Kern
Siegfried Raddatz
Juergen Reefschlaeger
Gunter Schmidt
Holger Zimmermann
Franz Zumpe
Martin Radtke
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10148598A external-priority patent/DE10148598A1/de
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG108272A publication Critical patent/BG108272A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BG108272A 2001-04-19 2003-10-14 Арилсулфонамиди като противовирусни средства BG108272A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19
DE10148598A DE10148598A1 (de) 2001-04-19 2001-10-02 Neue Arylsulfonamide als antivirale Mittel

Publications (1)

Publication Number Publication Date
BG108272A true BG108272A (bg) 2004-10-29

Family

ID=26009118

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108272A BG108272A (bg) 2001-04-19 2003-10-14 Арилсулфонамиди като противовирусни средства

Country Status (20)

Country Link
US (1) US7115612B2 (et)
EP (1) EP1383749B1 (et)
JP (1) JP4480941B2 (et)
CN (1) CN1516695A (et)
AT (1) ATE308529T1 (et)
BG (1) BG108272A (et)
BR (1) BR0209054A (et)
CA (1) CA2444123C (et)
DE (1) DE50204780D1 (et)
EE (1) EE200300515A (et)
ES (1) ES2252455T3 (et)
HU (1) HUP0303813A3 (et)
IL (1) IL158324A0 (et)
MX (1) MXPA03009548A (et)
NO (1) NO20034667L (et)
PL (1) PL363990A1 (et)
RU (1) RU2003133750A (et)
SK (1) SK12662003A3 (et)
UY (1) UY27263A1 (et)
WO (1) WO2002085869A1 (et)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20050168A2 (en) * 2002-08-23 2005-10-31 Rigel Pharmaceuticals Pyridyl substituted heterocycles useful for treating or preventing hcv infection
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
ES2770035T3 (es) 2003-04-11 2020-06-30 Ptc Therapeutics Inc Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades
DE102006009928A1 (de) * 2006-03-03 2007-09-06 Aicuris Gmbh & Co. Kg Substituierte Arylsulfonamide
WO2007117438A2 (en) 2006-03-30 2007-10-18 Ptc Therapeutics, Inc. Methods for the production of functional protein from dna having a nonsense mutation and the treatment of disorders associated therewith
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
JP2010531850A (ja) * 2007-07-02 2010-09-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規化合物
EP2177521A1 (en) * 2008-10-14 2010-04-21 Almirall, S.A. New 2-Amidothiadiazole Derivatives
EP2202232A1 (en) * 2008-12-26 2010-06-30 Laboratorios Almirall, S.A. 1,2,4-oxadiazole derivatives and their therapeutic use
RU2013103422A (ru) * 2010-06-28 2014-08-10 Байер Интеллектчуал Проперти Гмбх Гетероарил-замещенные пиридиновые соединения для применения в качестве пестицидов
EP2593434A1 (en) 2010-07-16 2013-05-22 Purdue Pharma LP Pyridine compounds as sodium channel blockers
WO2013136170A1 (en) 2012-03-16 2013-09-19 Purdue Pharma L.P. Substituted pyridines as sodium channel blockers
US9334249B2 (en) 2012-11-03 2016-05-10 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
WO2014070978A1 (en) * 2012-11-03 2014-05-08 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
US9714252B2 (en) 2012-12-20 2017-07-25 Purdue Pharma L.P. Cyclic sulfonamides as sodium channel blockers
CA2942147C (en) 2014-03-06 2022-12-13 Ptc Therapeutics, Inc. Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid
US10730866B2 (en) 2014-04-07 2020-08-04 Purdue Pharma L.P. Indole derivatives and use thereof
WO2016128541A1 (en) * 2015-02-13 2016-08-18 Azienda Ospedaliera Universitaria Senese Human helicase ddx3 inhibitors as therapeutic agents
CN108348527A (zh) 2015-10-30 2018-07-31 Ptc医疗公司 用于治疗癫痫的方法
SG11201909079PA (en) * 2017-03-31 2019-10-30 Perenna Pharmaceuticals Inc Compounds useful as inhibitors of alcat 1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802437A1 (de) * 1998-01-23 1999-07-29 Bayer Ag Verwendung von substituierten Sulfonamiden als anitvirale Mittel und neue Stoffe
WO2000063194A1 (en) * 1999-04-19 2000-10-26 Shionogi & Co., Ltd. Sulfonamide derivatives having oxadiazole rings

Also Published As

Publication number Publication date
PL363990A1 (en) 2004-11-29
CA2444123A1 (en) 2002-10-31
ATE308529T1 (de) 2005-11-15
EP1383749B1 (de) 2005-11-02
ES2252455T3 (es) 2006-05-16
SK12662003A3 (sk) 2004-04-06
IL158324A0 (en) 2004-05-12
WO2002085869A1 (de) 2002-10-31
CN1516695A (zh) 2004-07-28
DE50204780D1 (de) 2005-12-08
MXPA03009548A (es) 2004-05-24
UY27263A1 (es) 2002-11-29
US7115612B2 (en) 2006-10-03
NO20034667D0 (no) 2003-10-17
CA2444123C (en) 2010-09-21
EE200300515A (et) 2004-02-16
JP2004531536A (ja) 2004-10-14
HUP0303813A2 (hu) 2004-03-29
BR0209054A (pt) 2004-04-20
RU2003133750A (ru) 2005-05-10
NO20034667L (no) 2003-12-12
US20040176374A1 (en) 2004-09-09
JP4480941B2 (ja) 2010-06-16
HUP0303813A3 (en) 2005-05-30
EP1383749A1 (de) 2004-01-28

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