BG105664A - Use of apomophines for the treatment of organic erectile dysfunction in males - Google Patents
Use of apomophines for the treatment of organic erectile dysfunction in malesInfo
- Publication number
- BG105664A BG105664A BG105664A BG10566401A BG105664A BG 105664 A BG105664 A BG 105664A BG 105664 A BG105664 A BG 105664A BG 10566401 A BG10566401 A BG 10566401A BG 105664 A BG105664 A BG 105664A
- Authority
- BG
- Bulgaria
- Prior art keywords
- erectile dysfunction
- treatment
- apomophines
- males
- organic erectile
- Prior art date
Links
- 206010052004 Organic erectile dysfunction Diseases 0.000 title abstract 2
- 208000010228 Erectile Dysfunction Diseases 0.000 abstract 1
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 abstract 1
- 229960004046 apomorphine Drugs 0.000 abstract 1
- 201000001881 impotence Diseases 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000982 vasogenic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/213,567 US6291471B1 (en) | 1998-12-17 | 1998-12-17 | Use of apomorphine for the treatment of organic erectile dysfunction in males |
| PCT/US1999/029449 WO2000035457A1 (en) | 1998-12-17 | 1999-12-13 | Use of apomorphine in the manufacture of a medicament for the treatment of organic erectile dysfunction in males |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG105664A true BG105664A (en) | 2002-02-28 |
Family
ID=22795606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG105664A BG105664A (en) | 1998-12-17 | 2001-07-03 | Use of apomophines for the treatment of organic erectile dysfunction in males |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6291471B1 (xx) |
| EP (1) | EP1140094A1 (xx) |
| JP (1) | JP2003521462A (xx) |
| KR (1) | KR20010101241A (xx) |
| CN (1) | CN1335772A (xx) |
| AR (1) | AR021912A1 (xx) |
| AU (1) | AU2175800A (xx) |
| BG (1) | BG105664A (xx) |
| BR (1) | BR9916114A (xx) |
| CA (1) | CA2354601A1 (xx) |
| CZ (1) | CZ20012084A3 (xx) |
| HK (1) | HK1043303A1 (xx) |
| HU (1) | HUP0201618A3 (xx) |
| IL (1) | IL143410A0 (xx) |
| NO (1) | NO20012985L (xx) |
| NZ (1) | NZ511790A (xx) |
| PL (1) | PL354920A1 (xx) |
| SK (1) | SK8262001A3 (xx) |
| TR (1) | TR200101719T2 (xx) |
| TW (1) | TW577740B (xx) |
| WO (1) | WO2000035457A1 (xx) |
| ZA (1) | ZA200104146B (xx) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566368B2 (en) * | 1994-04-22 | 2003-05-20 | Pentech Pharmaceuticals, Inc. | Apomorphine-containing dosage form for ameliorating male erectile dysfunction |
| BR0005797A (pt) * | 2000-03-20 | 2001-10-16 | Abbott Lab | Métodos para o tratamento de disfunção sexual com apomorfina em nìveis de concentração plasmática especificados |
| BR0110450A (pt) * | 2000-11-22 | 2005-02-09 | Abbott Lab | Uso de agonistas receptores d4 de dopamina seletivo para tratamento de disfunção sexual |
| WO2002062315A1 (en) * | 2001-02-08 | 2002-08-15 | Pharmacia Corporation | Rapid-onset medicament for the treatment of sexual dysfunction |
| EP1496915A1 (en) * | 2002-03-19 | 2005-01-19 | Brain 'N' Beyond Biotech | Glycoside and orthoester glycoside derivatives of apomorphine, analogs, and uses thereof |
| SE0202365D0 (sv) | 2002-08-05 | 2002-08-05 | Pharmacia Ab | New formulation and use thereof |
| US20040204439A1 (en) * | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
| WO2004089374A1 (en) * | 2003-04-14 | 2004-10-21 | Vectura Ltd | Pharmaceutical compositions comprising apomorphine for pulmonary inhalation |
| AU2005232748A1 (en) | 2004-04-13 | 2005-10-27 | The Mclean Hospital Corporation | R(-)-11-hydroxyaporphine derivatives and uses thereof |
| GB2437488A (en) * | 2006-04-25 | 2007-10-31 | Optinose As | Pharmaceutical oily formulation for nasal or buccal administration |
| US8431591B2 (en) * | 2007-07-12 | 2013-04-30 | The Mclean Hospital Corporation | R(−)-2-methoxy-11-hydroxyaporphine and derivatives thereof |
| BRPI0800596A2 (pt) | 2008-01-31 | 2009-09-22 | Univ Minas Gerais | método para a potencialização da função erétil através do uso das composições farmacêuticas de toxina tx2-6 da aranha phoneutria nigriventer |
| CN102316875A (zh) | 2009-02-13 | 2012-01-11 | 贝林格尔.英格海姆国际有限公司 | 用于治疗i型糖尿病、ii型糖尿病、葡萄糖耐量降低或高血糖症的sglt-2抑制剂 |
| KR101890317B1 (ko) | 2010-12-16 | 2018-08-22 | 선오비온 파마슈티컬스 인코포레이티드 | 설하 필름 |
| KR101374500B1 (ko) * | 2012-10-09 | 2014-03-13 | 울산대학교 산학협력단 | R(-)-프로필노르아포모르핀을 유효성분으로 포함하는 암의 예방 또는 치료용 약학 조성물 |
| US11813275B2 (en) | 2013-04-05 | 2023-11-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| HK1213818A1 (zh) | 2013-04-05 | 2016-07-15 | 勃林格殷格翰国际有限公司 | 依帕列净的治疗用途 |
| ES2702174T3 (es) | 2013-04-05 | 2019-02-27 | Boehringer Ingelheim Int | Usos terapéuticos de empagliflozina |
| CA2812519A1 (en) | 2013-04-05 | 2014-10-05 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| DK2986304T3 (da) | 2013-04-18 | 2022-04-04 | Boehringer Ingelheim Int | Farmaceutisk sammensætning, fremgangsmåder til behandling og anvendelser deraf. |
| EP3288561B1 (en) * | 2015-04-30 | 2021-03-31 | Boehringer Ingelheim International GmbH | Methods and pharmaceutical compositions comprising a sglt2 inhibitor for treating or improving erectile dysfunction |
| WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
| CN109922813A (zh) | 2016-11-10 | 2019-06-21 | 勃林格殷格翰国际有限公司 | 药物组合物、治疗方法及其用途 |
| EP3807897A1 (en) * | 2018-06-14 | 2021-04-21 | AstraZeneca UK Limited | Methods for treating erectile dysfunction with a cgmp-specific phosphodiesterase 5 inhibitor pharmaceutical composition |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256652A (en) | 1987-11-12 | 1993-10-26 | Pharmedic Co. | Topical compositions and methods for treatment of male impotence |
| US5270323A (en) | 1990-05-31 | 1993-12-14 | Pfizer Inc. | Method of treating impotence |
| US5292520A (en) | 1990-09-13 | 1994-03-08 | Akzo N.V. | Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer |
| ATE241984T1 (de) | 1993-03-26 | 2003-06-15 | Franciscus Wilhelmus He Merkus | Pharmazeutische zusammensetzungen zur intranasalen verabreichung von apomorphin |
| PT758895E (pt) * | 1994-04-22 | 2000-05-31 | Univ Kingston | Formas de dosagem sublingual contendo apomorfina para uso no tratamento da disfuncao erectil |
| US5562917A (en) | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
| US5888534A (en) | 1995-06-13 | 1999-03-30 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| US5624677A (en) * | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| US5688499A (en) | 1996-03-13 | 1997-11-18 | Queen's University At Kingston | Antagonism of endothelin actions |
| DE19652268C2 (de) | 1996-12-16 | 2000-06-29 | Lohmann Therapie Syst Lts | Arzneizubereitung für die Freisetzung von Apomorphin in der Mundhöhle |
-
1998
- 1998-12-17 US US09/213,567 patent/US6291471B1/en not_active Expired - Fee Related
-
1999
- 1999-12-13 PL PL99354920A patent/PL354920A1/xx not_active Application Discontinuation
- 1999-12-13 TR TR2001/01719T patent/TR200101719T2/xx unknown
- 1999-12-13 SK SK826-2001A patent/SK8262001A3/sk unknown
- 1999-12-13 EP EP99966147A patent/EP1140094A1/en not_active Withdrawn
- 1999-12-13 CN CN99814559A patent/CN1335772A/zh active Pending
- 1999-12-13 NZ NZ511790A patent/NZ511790A/en unknown
- 1999-12-13 CA CA002354601A patent/CA2354601A1/en not_active Abandoned
- 1999-12-13 IL IL14341099A patent/IL143410A0/xx unknown
- 1999-12-13 HK HK02102415.1A patent/HK1043303A1/zh unknown
- 1999-12-13 BR BR9916114-1A patent/BR9916114A/pt not_active IP Right Cessation
- 1999-12-13 JP JP2000587777A patent/JP2003521462A/ja not_active Withdrawn
- 1999-12-13 CZ CZ20012084A patent/CZ20012084A3/cs unknown
- 1999-12-13 AU AU21758/00A patent/AU2175800A/en not_active Abandoned
- 1999-12-13 HU HU0201618A patent/HUP0201618A3/hu unknown
- 1999-12-13 WO PCT/US1999/029449 patent/WO2000035457A1/en not_active Ceased
- 1999-12-13 KR KR1020017007500A patent/KR20010101241A/ko not_active Ceased
- 1999-12-17 AR ARP990106551A patent/AR021912A1/es not_active Application Discontinuation
-
2000
- 2000-01-11 TW TW088122257A patent/TW577740B/zh not_active IP Right Cessation
-
2001
- 2001-05-21 ZA ZA200104146A patent/ZA200104146B/xx unknown
- 2001-06-15 NO NO20012985A patent/NO20012985L/no not_active Application Discontinuation
- 2001-07-03 BG BG105664A patent/BG105664A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20012985L (no) | 2001-08-16 |
| PL354920A1 (en) | 2004-03-22 |
| KR20010101241A (ko) | 2001-11-14 |
| AU2175800A (en) | 2000-07-03 |
| ZA200104146B (en) | 2002-08-21 |
| NO20012985D0 (no) | 2001-06-15 |
| EP1140094A1 (en) | 2001-10-10 |
| HK1043303A1 (zh) | 2002-09-13 |
| BR9916114A (pt) | 2003-01-14 |
| HUP0201618A3 (en) | 2003-03-28 |
| CN1335772A (zh) | 2002-02-13 |
| CA2354601A1 (en) | 2000-06-22 |
| JP2003521462A (ja) | 2003-07-15 |
| WO2000035457A1 (en) | 2000-06-22 |
| HUP0201618A2 (en) | 2002-09-28 |
| IL143410A0 (en) | 2002-04-21 |
| US6291471B1 (en) | 2001-09-18 |
| SK8262001A3 (en) | 2002-01-07 |
| CZ20012084A3 (cs) | 2002-01-16 |
| AR021912A1 (es) | 2002-09-04 |
| TR200101719T2 (tr) | 2002-08-21 |
| TW577740B (en) | 2004-03-01 |
| NZ511790A (en) | 2004-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BG105664A (en) | Use of apomophines for the treatment of organic erectile dysfunction in males | |
| MY119375A (en) | Treatment of tinnitus using neuroprotective agents | |
| BE2012C040I2 (xx) | ||
| MY130727A (en) | Controlled-release pharmaceutical formulations | |
| MY118526A (en) | Method for improving the pharmacokinetics of tipranavir | |
| BR9911060A (pt) | Composições compreendendo mono- ou dinitrato orgânico para tratar impotência | |
| UA41355C2 (uk) | Засіб для лікування нейро-сніду | |
| AU1711197A (en) | Method for treating sexual dysfunctions | |
| EP1108426A3 (en) | Use of prostaglandin agonists to treat erectile dysfunction or impotence | |
| IL143985A0 (en) | New use of melagatran | |
| WO1999065475A3 (en) | Combination of phentolamine and apomorphine for the treatment of human sexual function and dysfunction | |
| WO2000053148A3 (en) | Methods and compositions for treating erectile dysfunction | |
| BG106209A (en) | Therapeutic agents | |
| MX9604692A (es) | Derivados de quinoxalina para el tratamiento de tinnitus. | |
| IL146962A0 (en) | Aminotetralin derivatives for the therapy of cardiovascular diseases | |
| RU93058537A (ru) | Применение атипамезола для лечения мужской сексуальной импотенции | |
| WO1995005364A3 (en) | Inhibitors of biogenic amine transporters | |
| HK1039057A (en) | Use of apomorphine in the manufacture of a medicament for the treatment of organic erectile dysfunction in males | |
| NO304011B1 (no) | Anvendelse av atipamezol til fremstilling av et medisinsk preparat for behandling av menns impotens | |
| US6541495B1 (en) | Carboxylic acid derivatives as inhibitors of hyperproliferation diseases | |
| AU4918900A (en) | Interferon-beta use in the treatment of ewing's family of tumors | |
| ZA200006378B (en) | Compounds for the treatment of female sexual dysfunction. |