BE903674Q - ACID ESTERS 1- (BETHA-D-RIBOFURANNOSYL) -1,2,4-TRIAZOLE, THEIR PREPARATION AND THEIR USE - Google Patents
ACID ESTERS 1- (BETHA-D-RIBOFURANNOSYL) -1,2,4-TRIAZOLE, THEIR PREPARATION AND THEIR USEInfo
- Publication number
- BE903674Q BE903674Q BE0/215890A BE215890A BE903674Q BE 903674 Q BE903674 Q BE 903674Q BE 0/215890 A BE0/215890 A BE 0/215890A BE 215890 A BE215890 A BE 215890A BE 903674 Q BE903674 Q BE 903674Q
- Authority
- BE
- Belgium
- Prior art keywords
- acid esters
- ribofurannosyl
- betha
- triazole
- preparation
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- HZCAHMRRMINHDJ-DBRKOABJSA-N (2r,3s,4r,5r)-2-(hydroxymethyl)-5-(1,2,4-triazol-1-yl)oxolane-3,4-diol Chemical class O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 150000001733 carboxylic acid esters Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
On prépare des phosphates et des esters d'acide carboxylique de 1-(beta-D-ribofurannosyl)-1,2,4-triazoles par une série de procédés, ces composés étant doués d'une activité antivirale.Phosphates and carboxylic acid esters of 1- (beta-D-ribofuranosyl) -1,2,4-triazoles are prepared by a series of methods, these compounds being endowed with antiviral activity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/452,065 US3984396A (en) | 1971-06-01 | 1974-03-18 | 1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE903674Q true BE903674Q (en) | 1986-05-20 |
Family
ID=23794869
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE154411A BE826776R (en) | 1974-03-18 | 1975-03-17 | PRODUCTION OF 1,2,4-TRIAZOLE NUCLEOSIDES |
| BE0/215890A BE903674Q (en) | 1974-03-18 | 1985-11-19 | ACID ESTERS 1- (BETHA-D-RIBOFURANNOSYL) -1,2,4-TRIAZOLE, THEIR PREPARATION AND THEIR USE |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE154411A BE826776R (en) | 1974-03-18 | 1975-03-17 | PRODUCTION OF 1,2,4-TRIAZOLE NUCLEOSIDES |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS50154253A (en) |
| AR (1) | AR224992A1 (en) |
| BE (2) | BE826776R (en) |
| CA (1) | CA1060004A (en) |
| DE (2) | DE2511828A1 (en) |
| DK (1) | DK106375A (en) |
| ES (1) | ES435689A2 (en) |
| FR (1) | FR2264552B1 (en) |
| GB (1) | GB1482736A (en) |
| NL (1) | NL7503214A (en) |
| SE (1) | SE7502995L (en) |
| YU (2) | YU42137B (en) |
| ZA (1) | ZA751662B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9307043D0 (en) * | 1993-04-05 | 1993-05-26 | Norsk Hydro As | Chemical compounds |
| RU2001113268A (en) * | 1998-10-16 | 2003-09-27 | Шеринг Корпорейшн (US) | Combined therapy with ribavirin and interferon α to remove hepatitis C virus detected RNA in patients with chronic hepatitis C |
| US6277830B1 (en) | 1998-10-16 | 2001-08-21 | Schering Corporation | 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon |
| EP1282632A1 (en) | 2000-04-20 | 2003-02-12 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection |
| EP2198870A4 (en) | 2007-08-27 | 2011-08-03 | Univ Nagoya Nat Univ Corp | ACTIVATOR FOR BLOOD COAGULATION FACTOR VII PROMOTER AND USE THEREOF |
| WO2009028573A1 (en) | 2007-08-27 | 2009-03-05 | National University Corporation Nagoya University | Use of ribavirin in blood coagulation disorder |
| CN111205344B (en) * | 2020-01-14 | 2023-03-14 | 华东理工大学 | Pure organic phosphorescent small-molecule material for methanol solvent recognition and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3798209A (en) * | 1971-06-01 | 1974-03-19 | Icn Pharmaceuticals | 1,2,4-triazole nucleosides |
-
1975
- 1975-03-14 GB GB10724/75A patent/GB1482736A/en not_active Expired
- 1975-03-17 BE BE154411A patent/BE826776R/en active
- 1975-03-17 ES ES435689A patent/ES435689A2/en not_active Expired
- 1975-03-17 DK DK106375A patent/DK106375A/da unknown
- 1975-03-17 SE SE7502995A patent/SE7502995L/xx unknown
- 1975-03-18 CA CA222,365A patent/CA1060004A/en not_active Expired
- 1975-03-18 YU YU657/75A patent/YU42137B/en unknown
- 1975-03-18 ZA ZA00751662A patent/ZA751662B/en unknown
- 1975-03-18 JP JP50032822A patent/JPS50154253A/ja active Pending
- 1975-03-18 NL NL7503214A patent/NL7503214A/en not_active Application Discontinuation
- 1975-03-18 FR FR7508454A patent/FR2264552B1/fr not_active Expired
- 1975-03-18 DE DE19752511828 patent/DE2511828A1/en active Granted
- 1975-03-18 DE DE2560551A patent/DE2560551C2/de not_active Expired
-
1979
- 1979-03-18 AR AR258018A patent/AR224992A1/en active
-
1985
- 1985-11-19 BE BE0/215890A patent/BE903674Q/en not_active IP Right Cessation
-
1987
- 1987-01-23 YU YU92/87A patent/YU43291B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2511828A1 (en) | 1975-10-02 |
| BE826776R (en) | 1975-07-16 |
| DE2511828C2 (en) | 1991-01-17 |
| AR224992A1 (en) | 1982-02-15 |
| ES435689A2 (en) | 1977-10-16 |
| JPS50154253A (en) | 1975-12-12 |
| YU65775A (en) | 1983-01-21 |
| SE7502995L (en) | 1975-09-19 |
| YU43291B (en) | 1989-06-30 |
| ZA751662B (en) | 1976-02-25 |
| CA1060004A (en) | 1979-08-07 |
| AU7914575A (en) | 1976-09-23 |
| NL7503214A (en) | 1975-09-22 |
| YU42137B (en) | 1988-06-30 |
| YU9287A (en) | 1988-04-30 |
| GB1482736A (en) | 1977-08-10 |
| DK106375A (en) | 1975-09-19 |
| FR2264552A2 (en) | 1975-10-17 |
| DE2560551C2 (en) | 1989-02-23 |
| FR2264552B1 (en) | 1980-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: VIRATEK INC. Effective date: 19951130 |