BE905666A - PROCESS FOR THE PREPARATION OF DIETHYLENEGLYCOL ESTERS. - Google Patents
PROCESS FOR THE PREPARATION OF DIETHYLENEGLYCOL ESTERS.Info
- Publication number
- BE905666A BE905666A BE0/217337A BE217337A BE905666A BE 905666 A BE905666 A BE 905666A BE 0/217337 A BE0/217337 A BE 0/217337A BE 217337 A BE217337 A BE 217337A BE 905666 A BE905666 A BE 905666A
- Authority
- BE
- Belgium
- Prior art keywords
- preparation
- esters
- diethylene glycol
- diethyleneglycol
- reaction
- Prior art date
Links
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical class OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procédé de préparation d'esters de diéthylèneglycol, obtenus en une seule étape, c'est-à-dire en utilisant le diéthylène glycol avec l'acide correspondant, et en lui ajoutant du chlorure de thionyle en quantités stoechiométriques par rapport à l'acide ou meme en quantités supérieures, et en effectuant la réaction entre la température ambiante et le bain-marie, cette réaction s'effectuant sans besoin de protéger les hydroxyles du diéthylèneglycol.Process for the preparation of diethylene glycol esters, obtained in a single step, that is to say by using diethylene glycol with the corresponding acid, and by adding thionyl chloride to it in stoichiometric amounts relative to the acid or even in higher quantities, and by carrying out the reaction between room temperature and the water bath, this reaction being carried out without the need to protect the hydroxyls of diethylene glycol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES548226A ES8605220A1 (en) | 1985-10-25 | 1985-10-25 | Esters of diethylene glycol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE905666A true BE905666A (en) | 1987-02-16 |
Family
ID=8490031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/217337A BE905666A (en) | 1985-10-25 | 1986-10-27 | PROCESS FOR THE PREPARATION OF DIETHYLENEGLYCOL ESTERS. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS62106064A (en) |
| BE (1) | BE905666A (en) |
| CH (1) | CH676238A5 (en) |
| DE (1) | DE3636125A1 (en) |
| ES (1) | ES8605220A1 (en) |
| FR (1) | FR2589151B1 (en) |
| GB (1) | GB2182041B (en) |
| IT (1) | IT1197255B (en) |
| PT (1) | PT81505B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3811118C1 (en) * | 1988-03-31 | 1989-10-12 | Merckle Gmbh, 7902 Blaubeuren, De | |
| US9217066B2 (en) | 2008-03-31 | 2015-12-22 | Ford Global Technologies, Llc | Structural polymer insert and method of making the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1939112C3 (en) * | 1969-08-01 | 1975-03-06 | Troponwerke Dinklage & Co, 5000 Koeln | Esters of N- (3-trifluoromethylphenyl) anthranilic acid, process for their preparation and pharmacologically active preparations thereof |
| DE2735569A1 (en) * | 1977-08-06 | 1979-02-15 | Troponwerke Gmbh & Co Kg | Antiinflammatory and antirheumatic agent prodn. - esp. N-tri:fluoro:methyl-phenyl-anthranilic acid hydroxy-ethoxy-ethyl ester |
| DE2834169C2 (en) * | 1978-08-04 | 1984-02-09 | Troponwerke GmbH & Co KG, 5000 Köln | Process for the preparation of 2- (2-hydroxyethoxy) ethyl-N- (alpha, alpha, alpha -trifluoro-m-tolyl) anthranilate |
| DE2834167C2 (en) * | 1978-08-04 | 1984-01-26 | Troponwerke GmbH & Co KG, 5000 Köln | Process for the preparation of 2- (2-hydroxyethoxy) ethyl-N - (α, α, α-trifluoro-m-tolyl) anthranilate |
| DE2834168C2 (en) * | 1978-08-04 | 1984-02-09 | Troponwerke GmbH & Co KG, 5000 Köln | Process for the preparation of 2- (2-hydroxyethoxy) ethyl-N - (α, α, α-trifluoro-m-tolyl) anthranilate |
| DE2926472A1 (en) * | 1979-06-30 | 1981-01-15 | Thomae Gmbh Dr K | NEW BENZOYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS |
| IL67445A (en) * | 1982-12-09 | 1985-11-29 | Teva Pharma | Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids |
| EP0132690B1 (en) * | 1983-07-21 | 1989-02-01 | Troponwerke GmbH & Co. KG | Thermoplastics containing antiphlogistics |
| US4694105A (en) * | 1983-12-20 | 1987-09-15 | Ciba-Geigy Corporation | Herbicidal alkoxyamino- and polyalkoxyaminodiphenyl ethers |
| DE3407507A1 (en) * | 1984-03-01 | 1985-09-05 | A. Nattermann & Cie GmbH, 5000 Köln | Novel o-(2,6-dichloroanilino)phenylacetic acid esters, process for their preparation, and pharmaceutical preparations containing them |
-
1985
- 1985-10-25 ES ES548226A patent/ES8605220A1/en not_active Expired
- 1985-11-15 PT PT81505A patent/PT81505B/en not_active IP Right Cessation
-
1986
- 1986-09-19 IT IT21774/86A patent/IT1197255B/en active
- 1986-10-22 CH CH3810/86A patent/CH676238A5/de not_active IP Right Cessation
- 1986-10-23 DE DE19863636125 patent/DE3636125A1/en not_active Ceased
- 1986-10-24 GB GB8625481A patent/GB2182041B/en not_active Expired
- 1986-10-24 JP JP61252159A patent/JPS62106064A/en active Pending
- 1986-10-27 FR FR868614922A patent/FR2589151B1/en not_active Expired - Lifetime
- 1986-10-27 BE BE0/217337A patent/BE905666A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2589151B1 (en) | 1990-05-18 |
| IT8621774A1 (en) | 1988-03-19 |
| CH676238A5 (en) | 1990-12-28 |
| PT81505B (en) | 1987-11-11 |
| ES548226A0 (en) | 1986-03-16 |
| GB2182041A (en) | 1987-05-07 |
| PT81505A (en) | 1985-12-01 |
| GB8625481D0 (en) | 1986-11-26 |
| GB2182041B (en) | 1989-09-20 |
| ES8605220A1 (en) | 1986-03-16 |
| IT1197255B (en) | 1988-11-30 |
| FR2589151A1 (en) | 1987-04-30 |
| IT8621774A0 (en) | 1986-09-19 |
| DE3636125A1 (en) | 1987-04-30 |
| JPS62106064A (en) | 1987-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEU Effective date: 19941031 |