BE888811A - 1- (4-CHLOROBENZHYDRYL) -4- (2,3-BIS-HYDROXYPROPYL) -PIPERAZINE, HAVE BEEN USED AS ANTI-COVERAGE, ANTI-HISTAMINIC SEDATIVE, ANALGETIC AND ANTI-INFLAMMATIVE PREPARATOR, WITH FARM PRODUCT. - Google Patents
1- (4-CHLOROBENZHYDRYL) -4- (2,3-BIS-HYDROXYPROPYL) -PIPERAZINE, HAVE BEEN USED AS ANTI-COVERAGE, ANTI-HISTAMINIC SEDATIVE, ANALGETIC AND ANTI-INFLAMMATIVE PREPARATOR, WITH FARM PRODUCT.Info
- Publication number
- BE888811A BE888811A BE2/59160A BE2059160A BE888811A BE 888811 A BE888811 A BE 888811A BE 2/59160 A BE2/59160 A BE 2/59160A BE 2059160 A BE2059160 A BE 2059160A BE 888811 A BE888811 A BE 888811A
- Authority
- BE
- Belgium
- Prior art keywords
- inflammative
- preparator
- chlorobenzhydryl
- histaminic
- analgetic
- Prior art date
Links
- VPDMYBDGTOUQJE-UHFFFAOYSA-N 3-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]propane-1,2-diol Chemical compound C1CN(CC(O)CO)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 VPDMYBDGTOUQJE-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- 239000000932 sedative agent Substances 0.000 title 1
- 230000001624 sedative effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22283/80A IT1140978B (en) | 1980-05-23 | 1980-05-23 | 1- (4-CHLOROBENZIDRIL) -4- (2,3-DIIDROS SIPROPIL) -PIPERAZINE, METHODS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE888811A true BE888811A (en) | 1981-08-28 |
Family
ID=11194137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2/59160A BE888811A (en) | 1980-05-23 | 1981-05-15 | 1- (4-CHLOROBENZHYDRYL) -4- (2,3-BIS-HYDROXYPROPYL) -PIPERAZINE, HAVE BEEN USED AS ANTI-COVERAGE, ANTI-HISTAMINIC SEDATIVE, ANALGETIC AND ANTI-INFLAMMATIVE PREPARATOR, WITH FARM PRODUCT. |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5731678A (en) |
| BE (1) | BE888811A (en) |
| DE (1) | DE3118162C2 (en) |
| ES (1) | ES502429A0 (en) |
| FR (1) | FR2482965A1 (en) |
| GB (1) | GB2076403B (en) |
| IT (1) | IT1140978B (en) |
| NL (1) | NL8102361A (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3611276A1 (en) * | 1986-04-04 | 1987-11-26 | Unilever Nv | PACKING WITH MARGARINE OR SIMILAR BREAD |
| JPH01226575A (en) * | 1988-02-25 | 1989-09-11 | Mitsubishi Plastics Ind Ltd | Packed body of seaweed |
| SE9504661D0 (en) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| SE9904674D0 (en) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE9904673D0 (en) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE0001209D0 (en) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| AR035974A1 (en) | 2001-05-18 | 2004-07-28 | Astrazeneca Ab | DERIVATIVES OF DIARILMETIL PIPERAZINA, PROCESSES FOR THEIR PREPARATION, USE OF THESE DERIVATIVES FOR THE PREPARATION OF MEDICINES AND PHARMACEUTICAL COMPOSITION |
| SE0203303D0 (en) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203300D0 (en) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203302D0 (en) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| HRP20120343T1 (en) | 2004-08-02 | 2012-05-31 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
| HU227074B1 (en) * | 2005-12-08 | 2010-06-28 | Egis Gyogyszergyar Nyrt | An optically active carbamic acid derivative, method for producing the same and use as a pharmaceutical intermediate |
| EP2062881B1 (en) * | 2007-11-21 | 2011-02-23 | Synthon B.V. | Process for making N-(diphenylmethyl)piperazines |
| US7989623B2 (en) | 2007-11-21 | 2011-08-02 | Synthon Bv | Process for making n-(diphenylmethyl)piperazines |
-
1980
- 1980-05-23 IT IT22283/80A patent/IT1140978B/en active
-
1981
- 1981-05-07 DE DE3118162A patent/DE3118162C2/en not_active Expired
- 1981-05-08 FR FR8109273A patent/FR2482965A1/en active Granted
- 1981-05-13 NL NL8102361A patent/NL8102361A/en not_active Application Discontinuation
- 1981-05-15 BE BE2/59160A patent/BE888811A/en not_active IP Right Cessation
- 1981-05-22 GB GB8115827A patent/GB2076403B/en not_active Expired
- 1981-05-22 ES ES502429A patent/ES502429A0/en active Granted
- 1981-05-23 JP JP7856281A patent/JPS5731678A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2482965B1 (en) | 1984-11-23 |
| DE3118162A1 (en) | 1982-02-18 |
| NL8102361A (en) | 1981-12-16 |
| JPS6135189B2 (en) | 1986-08-12 |
| GB2076403A (en) | 1981-12-02 |
| JPS5731678A (en) | 1982-02-20 |
| ES8203352A1 (en) | 1982-04-01 |
| IT1140978B (en) | 1986-10-10 |
| FR2482965A1 (en) | 1981-11-27 |
| ES502429A0 (en) | 1982-04-01 |
| GB2076403B (en) | 1983-11-16 |
| DE3118162C2 (en) | 1984-07-26 |
| IT8022283A0 (en) | 1980-05-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE26450T1 (en) | MUCOPOLYSACCHARIDES WITH BIOLOGICAL PROPERTIES, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS. | |
| BE888811A (en) | 1- (4-CHLOROBENZHYDRYL) -4- (2,3-BIS-HYDROXYPROPYL) -PIPERAZINE, HAVE BEEN USED AS ANTI-COVERAGE, ANTI-HISTAMINIC SEDATIVE, ANALGETIC AND ANTI-INFLAMMATIVE PREPARATOR, WITH FARM PRODUCT. | |
| ATE5964T1 (en) | DICHLOROQUINOLINE DERIVATIVES, THEIR PRODUCTION, THEIR USE AS HERBICIDES AND MEANS THEREOF. | |
| DE3581613D1 (en) | TRIAZOLE DERIVATIVES, THE PRODUCTION AND USE THEREOF AS A PEST CONTROL. | |
| IT1214906B (en) | HINGE, IN PARTICULAR FOR FURNITURE. | |
| DE3480794D1 (en) | REACTIVE DYES, THEIR PRODUCTION AND USE. | |
| DE3480696D1 (en) | LAMINATE, ITS PRODUCTION AND USE. | |
| DE3687130D1 (en) | PYRAZOLE DERIVATIVES, THEIR PRODUCTION AND USE. | |
| DE3579389D1 (en) | PHENOTHIAZINE, THEIR PRODUCTION AND USE IN ELECTROCHROMIC RECORDING MATERIALS. | |
| DE3876846D1 (en) | MORPHOLINE DERIVATIVES AND THEIR USE. | |
| CH671314B (en) | AQUEOUS WAX DISPERSIONS, THEIR PRODUCTION AND USE. | |
| NZ183396A (en) | Heterocyclic compounds with histamine h2-antagonist activity, and pharmaceutical compositions | |
| ATE5653T1 (en) | N-ACYLATED ALPHA-NAPHTHYLAMINES, THEIR PRODUCTION AND USE AS PLANT FUNGICIDES, AND PLANT FUNGICIDES CONTAINING THEM. | |
| DE3770739D1 (en) | MORPHOLINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS FUNGICIDES. | |
| ATE1944T1 (en) | N,N-DISUBSTITUTED ETHYLGLYCINE ESTERS, THEIR PRODUCTION AND USE, FUNCIDES CONTAINING THEM AND THEIR PRODUCTION. | |
| DE3584652D1 (en) | 2,2,6,6-TETRAMETHYL-4-PIPERIDINYL DERIVATIVES AND THEIR USE AS LIGHT STABILIZERS. | |
| ATE8882T1 (en) | SUBSTITUTED Succinic IMIIDES AND THEIR USE AS FUNGICIDES. | |
| IT8102916A0 (en) | FURNITURE HINGE. | |
| DE3685743D1 (en) | ANTHRACYCLINE DERIVATIVES, THEIR USE AS ANTITUARY SUBSTANCES AND THEIR PRODUCTION. | |
| ATE16184T1 (en) | NEW BENZTRIAZOLES, THEIR PRODUCTION AND USE AS PHARMACEUTICALS. | |
| DE3671892D1 (en) | (2-CYANO-2-ARYLETHYL) -PYRIDINE, THEIR PRODUCTION AND USE AS A FUNGICIDE. | |
| DE3676632D1 (en) | 5-ARYL-2,4-DIALKYL-3H-1,2,4-TRIAZOL-3-THIONE AND THEIR USE AS AN ANTIDEPRESSIVE. | |
| ATE7912T1 (en) | 1-(3,5-DICHLOROBENZOYL)-3-PHENYLPYRAZOLINE AND THEIR USE AS POWDER DELICATES. | |
| DE3889336D1 (en) | ALKYL TETRAMETHYLCYCLOHEXANE DERIVATIVES AND THE USE THEREOF AS A FRAGRANCE. | |
| MX9203174A (en) | PHARMACEUTICAL COMPOSITION WITH ANTI-PHYLOGISTIC, ANTI-PYRECTIC AND ANTALGICAL ACTIVITY. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: SELVI & C. S.P.A. Effective date: 19930531 |