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BE849311A - Nouveau procede de synthese de la 3',4'-didesoxykanamycine b. - Google Patents

Nouveau procede de synthese de la 3',4'-didesoxykanamycine b.

Info

Publication number
BE849311A
BE849311A BE173181A BE173181A BE849311A BE 849311 A BE849311 A BE 849311A BE 173181 A BE173181 A BE 173181A BE 173181 A BE173181 A BE 173181A BE 849311 A BE849311 A BE 849311A
Authority
BE
Belgium
Prior art keywords
didesoxykanamycin
synthesis
new process
new
Prior art date
Application number
BE173181A
Other languages
English (en)
Inventor
H Umezawa
S Umezawa
T Tsuchiya
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE849311A publication Critical patent/BE849311A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BE173181A 1975-12-11 1976-12-10 Nouveau procede de synthese de la 3',4'-didesoxykanamycine b. BE849311A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50146903A JPS6029720B2 (ja) 1975-12-11 1975-12-11 ３′，４′‐ジデオキシカナマイシンｂの新規な製造法

Publications (1)

Publication Number Publication Date
BE849311A true BE849311A (fr) 1977-06-10

Family

ID=15418164

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173181A BE849311A (fr) 1975-12-11 1976-12-10 Nouveau procede de synthese de la 3',4'-didesoxykanamycine b.

Country Status (11)

Country Link
US (1) US4156078A (fr)
JP (1) JPS6029720B2 (fr)
BE (1) BE849311A (fr)
CA (1) CA1075684A (fr)
DE (1) DE2655731C3 (fr)
DK (1) DK159787C (fr)
FR (1) FR2336412A1 (fr)
GB (1) GB1555661A (fr)
HU (1) HU176356B (fr)
NL (1) NL7613706A (fr)
YU (3) YU41292B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU177398B (en) * 1976-12-16 1981-12-28 Microbial Chem Res Found New process for producing 3:4'-dideoxi-kanamycin b
JPS5581897A (en) * 1978-12-14 1980-06-20 Microbial Chem Res Found Preparation of 1-n-isoseryl-or 1-n-(l-4-amino-2-hydroxybutyryl)-3',4'-dideoxykanamycin b
JPS55105699A (en) * 1979-02-05 1980-08-13 Microbial Chem Res Found 3',4'-dideoxykanamycin a and its 1-n-aminoalkanoyl derivative
JPS5643297A (en) * 1979-09-19 1981-04-21 Microbial Chem Res Found 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation
JPS5663993A (en) * 1979-10-30 1981-05-30 Microbial Chem Res Found Novel preparation of tobramycin
US4438109A (en) 1980-07-25 1984-03-20 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Tylosin derivatives
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin
US5488038A (en) * 1992-11-27 1996-01-30 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Dibekacin derivatives and arbekacin derivatives active against resistant bacteria
CN101575354B (zh) * 2009-05-26 2013-03-13 北京化工大学 阿贝卡星及其中间体地贝卡星的合成方法
CN102786564B (zh) * 2011-05-19 2015-05-13 北京化工大学 阿贝卡星及其中间体地贝卡星的合成新方法
CN106946957B (zh) * 2017-05-11 2019-11-08 常州方圆制药有限公司 阿贝卡星中间体的制备方法
JP7271519B2 (ja) * 2017-06-05 2023-05-11 エロックス ファーマシューティカルズ リミテッド アミノグリコシド誘導体及び遺伝子疾患の治療におけるその使用
CN115716856B (zh) * 2022-11-14 2025-04-25 北京耀诚惠仁科技有限公司 一种合成氨基糖苷类抗生素阿贝卡星的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1349302A (en) * 1970-07-29 1974-04-03 Microbial Chem Res Found 3,-4,-dideoxykanamycin b active against resistant bacteria and its synthesis
USRE28647E (en) 1971-06-02 1975-12-09 Preparation of 3-4 dideoxykanamycin B active against resistant bacteria
US3929762A (en) * 1972-08-23 1975-12-30 Microbial Chem Res Found 3{40 -Deoxy derivatives of neamine and its related aminoglycosidic antibiotics, and the production thereof
US3868360A (en) * 1972-10-24 1975-02-25 Schering Corp Process for preparing 2-deroxy-3-desamino-2,3-epimino-aminoglycosides and intermediates useful therein

Also Published As

Publication number Publication date
DE2655731A1 (de) 1977-06-23
DE2655731B2 (de) 1981-08-06
CA1075684A (fr) 1980-04-15
NL7613706A (nl) 1977-06-14
FR2336412A1 (fr) 1977-07-22
YU42129B (en) 1988-04-30
GB1555661A (en) 1979-11-14
YU146285A (en) 1986-06-30
YU41292B (en) 1987-02-28
FR2336412B1 (fr) 1980-09-26
DK159787C (da) 1991-04-22
YU42084B (en) 1988-04-30
YU299776A (en) 1982-06-30
JPS5271446A (en) 1977-06-14
HU176356B (en) 1981-01-28
YU146385A (en) 1986-06-30
JPS6029720B2 (ja) 1985-07-12
DK159787B (da) 1990-12-03
DK554076A (da) 1977-06-12
US4156078A (en) 1979-05-22
DE2655731C3 (de) 1982-04-29

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI

Effective date: 19961210