|
JP4564713B2
(en)
|
2000-11-01 |
2010-10-20 |
ミレニアム・ファーマシューティカルズ・インコーポレイテッド |
Nitrogen heterocyclic compounds, and methods for making nitrogen heterocyclic compounds and intermediates thereof
|
|
RU2324682C2
(en)
*
|
2002-10-15 |
2008-05-20 |
Оцука Фармасьютикал Ко., Лтд. |
1-substituted 4-nitroimidazole derivative and method of its production
|
|
ES2314460T3
(en)
*
|
2003-10-31 |
2009-03-16 |
Otsuka Pharmaceutical Co., Ltd. |
COMPOUNDS OF 2,3-DIHIDRO-6-NITROIMIDAZO (2,1-B) OXAZOL FOR THE TREATMENT OF TUBERCULOSIS.
|
|
JP4761756B2
(en)
*
|
2003-10-31 |
2011-08-31 |
大塚製薬株式会社 |
2,3-Dihydroimidazo [2,1-b] oxazole compound
|
|
TWI300409B
(en)
|
2004-02-18 |
2008-09-01 |
Otsuka Pharma Co Ltd |
Method for producing 4-nitroimidazole compound
|
|
BRPI0509292B1
(en)
|
2004-03-31 |
2015-06-23 |
Nippon Soda Co |
Cyclic Amine Compound and Composition
|
|
JP4787529B2
(en)
*
|
2004-04-09 |
2011-10-05 |
大塚製薬株式会社 |
Pharmaceutical composition
|
|
JP4789966B2
(en)
*
|
2004-04-09 |
2011-10-12 |
大塚製薬株式会社 |
Pharmaceutical composition
|
|
US7408066B2
(en)
*
|
2005-06-20 |
2008-08-05 |
Schering Corproation |
Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists
|
|
SI1906926T1
(en)
*
|
2005-07-28 |
2011-02-28 |
Otsuka Pharma Co Ltd |
PHARMACEUTICAL COMPOSITION COMPRISING 2,3-DIHYDRO-6-NITROIMIDAZO?á2,1-B?åOXAZOLE DERIVATIVES
|
|
JP5105818B2
(en)
*
|
2005-10-05 |
2012-12-26 |
大塚製薬株式会社 |
Pharmaceutical composition
|
|
TW201233389A
(en)
*
|
2005-10-05 |
2012-08-16 |
Otsuka Pharma Co Ltd |
Antituberculous therapeutic drugs and kit containing the same
|
|
CN102936221B
(en)
*
|
2005-10-06 |
2014-09-10 |
日本曹达株式会社 |
Bridged cyclic amine compound and pest control agent
|
|
TW200800268A
(en)
*
|
2005-11-04 |
2008-01-01 |
Otsuka Pharma Co Ltd |
Medicinal composition showing improved drug absorbability
|
|
AU2006333522A1
(en)
|
2005-12-21 |
2007-07-12 |
Decode Genetics, Ehf. |
Biaryl nitrogen heterocycle inhibitors of LTA4H for treating inflammation
|
|
WO2007093557A1
(en)
*
|
2006-02-13 |
2007-08-23 |
Laboratoires Serono S.A. |
Sulfonamide derivatives for the treatment of bacterial infections
|
|
JP2007297305A
(en)
*
|
2006-04-28 |
2007-11-15 |
Daiso Co Ltd |
Method for producing n-(2,3-epoxy-2-methylpropyl)phthalimide
|
|
JP5486928B2
(en)
*
|
2007-02-26 |
2014-05-07 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
|
AR070301A1
(en)
*
|
2007-05-08 |
2010-03-31 |
Otsuka Pharma Co Ltd |
EPOXY COMPOUND AND METHOD TO PRODUCE THE SAME
|
|
EP2183229B1
(en)
*
|
2007-07-26 |
2012-04-18 |
Vitae Pharmaceuticals, Inc. |
Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
|
|
TW200922581A
(en)
*
|
2007-08-15 |
2009-06-01 |
Glaxo Group Ltd |
Compounds
|
|
EP2205585A1
(en)
*
|
2007-10-16 |
2010-07-14 |
Glaxo Group Limited |
Quinoline derivatives used to treat inflammatory and allergic diseases
|
|
AR069207A1
(en)
*
|
2007-11-07 |
2010-01-06 |
Vitae Pharmaceuticals Inc |
CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1
|
|
WO2009075835A1
(en)
|
2007-12-11 |
2009-06-18 |
Vitae Pharmaceutical, Inc |
CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
|
|
TW200934490A
(en)
*
|
2008-01-07 |
2009-08-16 |
Vitae Pharmaceuticals Inc |
Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
|
|
WO2009094169A1
(en)
|
2008-01-24 |
2009-07-30 |
Vitae Pharmaceuticals, Inc. |
Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
CA2714532A1
(en)
*
|
2008-02-11 |
2009-08-20 |
Vitae Pharmaceuticals, Inc. |
1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
|
|
US8598160B2
(en)
*
|
2008-02-15 |
2013-12-03 |
Vitae Pharmaceuticals, Inc. |
Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
|
WO2009117109A1
(en)
*
|
2008-03-18 |
2009-09-24 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
|
|
US7666864B2
(en)
*
|
2008-03-26 |
2010-02-23 |
Global Alliance For Tb Drug Development |
Bicyclic nitroimidazole-substituted phenyl oxazolidinones
|
|
ES2421537T3
(en)
|
2008-05-01 |
2013-09-03 |
Vitae Pharmaceuticals Inc |
Cyclic 11beta-hydroxysteroid dehydrogenase 1 inhibitors
|
|
CA2723039A1
(en)
|
2008-05-01 |
2009-11-05 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
CA2723034A1
(en)
|
2008-05-01 |
2009-11-05 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
JP5451752B2
(en)
*
|
2008-05-01 |
2014-03-26 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1
|
|
US8846668B2
(en)
|
2008-07-25 |
2014-09-30 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
DK2324018T3
(en)
|
2008-07-25 |
2013-10-14 |
Boehringer Ingelheim Int |
CYCLE INHIBITORS OF 11 BETA-HYDROXYSTEROID DEHYDROGENASE 1
|
|
US9643922B2
(en)
|
2008-08-18 |
2017-05-09 |
Yale University |
MIF modulators
|
|
US9540322B2
(en)
|
2008-08-18 |
2017-01-10 |
Yale University |
MIF modulators
|
|
CA2733554A1
(en)
*
|
2008-08-18 |
2010-02-25 |
Yale University |
Mif modulators
|
|
US8558005B2
(en)
|
2008-08-21 |
2013-10-15 |
Dynamit Nobel Gmbh Explosivstoff-Und Systemtechnik |
Methods for the production of 2-halo-4-nitroimidazole and intermediates thereof
|
|
WO2010143007A1
(en)
*
|
2009-06-10 |
2010-12-16 |
Dynamit Nobel Gmbh Explosivstoff-Und Systemtechnik |
Method for the production of 2-halogeno-4-nitroimidazole
|
|
EP2393807B1
(en)
|
2009-02-04 |
2013-08-14 |
Boehringer Ingelheim International GmbH |
Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1
|
|
TW201039034A
(en)
*
|
2009-04-27 |
2010-11-01 |
Chunghwa Picture Tubes Ltd |
Pixel structure and the method of forming the same
|
|
US8680093B2
(en)
|
2009-04-30 |
2014-03-25 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
KR20120061771A
(en)
*
|
2009-04-30 |
2012-06-13 |
비타이 파마슈티컬즈, 인코포레이티드 |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
EP2440537A1
(en)
|
2009-06-11 |
2012-04-18 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
|
|
WO2011002910A1
(en)
|
2009-07-01 |
2011-01-06 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
AU2010278779B2
(en)
*
|
2009-07-31 |
2014-08-14 |
Global Alliance For Tb Drug Development |
Nitroimidazooxazine and nitroimidazooxazole analogues and their uses
|
|
US9198913B2
(en)
|
2009-07-31 |
2015-12-01 |
Global Alliance For Tb Drug Development |
Nitroimidazooxazines and their uses in anti-tubercular therapy
|
|
CA2769359C
(en)
*
|
2009-07-31 |
2017-03-07 |
Global Alliance For Tb Drug Development |
Nitroimidazooxazines and their uses in anti-tubercular therapy
|
|
WO2011052522A1
(en)
|
2009-10-26 |
2011-05-05 |
富士フイルムRiファーマ株式会社 |
Diagnostic agent for infectious diseases
|
|
TW201200523A
(en)
*
|
2010-01-29 |
2012-01-01 |
Otsuka Pharma Co Ltd |
Synthetic intermediate of oxazole compound and method for producing the same
|
|
GB201012209D0
(en)
*
|
2010-05-31 |
2010-09-08 |
Ge Healthcare Ltd |
In vivo imaging agent
|
|
WO2011159760A1
(en)
|
2010-06-16 |
2011-12-22 |
Vitae Pharmaceuticals, Inc. |
Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
|
|
JP5813106B2
(en)
|
2010-06-25 |
2015-11-17 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Azaspirohexanone as an inhibitor of 11-β-HSD1 for the treatment of metabolic disorders
|
|
EA201300522A1
(en)
|
2010-11-02 |
2013-11-29 |
Бёрингер Ингельхайм Интернациональ Гмбх |
PHARMACEUTICAL COMBINATIONS FOR THE TREATMENT OF METABOLIC DISORDERS
|
|
CN103596960B
(en)
|
2011-04-15 |
2016-11-16 |
大塚制药株式会社 |
6,7-Dihydroimidazo[2,1-B][1,3]oxazine fungicide
|
|
JP2015006994A
(en)
*
|
2011-10-28 |
2015-01-15 |
大正製薬株式会社 |
Dihydroimidazooxazole derivative
|
|
US9572809B2
(en)
|
2012-07-18 |
2017-02-21 |
Spero Trinem, Inc. |
Combination therapy to treat Mycobacterium diseases
|
|
FR3000064A1
(en)
*
|
2012-12-21 |
2014-06-27 |
Univ Lille Ii Droit & Sante |
SPIROISOXAZOLINE-LIKE COMPOUNDS WITH POTENTIALIZING ACTIVITY OF AN ANTIBIOTIC COMPOSITION AND PHARMACEUTICAL PRODUCT COMPRISING SUCH COMPOUNDS
|
|
JP6532457B2
(en)
*
|
2013-10-04 |
2019-06-19 |
カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ |
6-Nitro-2,3-dihydroimidazo [2,1-b] oxazoles and processes for their preparation
|
|
CN103524492A
(en)
*
|
2013-10-23 |
2014-01-22 |
中国药科大学 |
Quinolones compound with side chain containing nitroimidazole group substitution as well as preparation and use thereof
|
|
TWI687409B
(en)
|
2014-08-28 |
2020-03-11 |
日商大塚製藥股份有限公司 |
Fused heterocyclic compounds
|
|
JP6467042B2
(en)
*
|
2014-10-21 |
2019-02-06 |
カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ |
Substituted 1,2,3-triazol-1-yl-methyl-2,3-dihydro-2-methyl-6-nitroimidazo [2,1-b] oxazole as antimycobacterial agent and method for its preparation
|
|
CN105732659B
(en)
*
|
2014-12-12 |
2019-07-16 |
上海阳帆医药科技有限公司 |
Nitro glyoxaline compound and preparation method thereof and the purposes in pharmacy
|
|
TW201632533A
(en)
*
|
2015-01-29 |
2016-09-16 |
南京明德新藥研發股份有限公司 |
The nitroimidazole derivative for anti- tuberculosis uberculosis
|
|
KR102597449B1
(en)
*
|
2015-03-27 |
2023-11-03 |
오츠카 세이야쿠 가부시키가이샤 |
Method for producing 1-(4-hydroxyphenyl)-4-(4-trifluoromethoxyphenoxy)piperidine or its salt
|
|
CN106317072B
(en)
*
|
2015-06-17 |
2020-03-17 |
盟科医药技术(上海)有限公司 |
Heterocyclic compounds for the treatment of mycobacterial infections and uses thereof
|
|
US10851079B2
(en)
|
2016-02-26 |
2020-12-01 |
Otsuka Pharmaceutical Co., Ltd. |
Piperidine derivative
|
|
CN105859628B
(en)
*
|
2016-04-19 |
2018-08-07 |
清远职业技术学院 |
A kind of antimicrobial compound is to N imidazoles benzaldehyde contracting ortho-aminotoluene schiff bases and its preparation method and application
|
|
MX2019000858A
(en)
*
|
2016-07-22 |
2019-11-11 |
Medshine Discovery Inc |
Crystal and salt of nitroimidazole, and manufacturing method thereof.
|
|
WO2019034700A1
(en)
*
|
2017-08-16 |
2019-02-21 |
Glaxosmithkline Intellectual Property Development Limited |
Novel compounds
|
|
EP3804720A4
(en)
|
2018-06-11 |
2022-02-09 |
Otsuka Pharmaceutical Co., Ltd. |
Delamanid-containing composition
|
|
CN109705022A
(en)
*
|
2018-12-28 |
2019-05-03 |
上海彩迩文生化科技有限公司 |
A kind of preparation method of aromatic amine intermediate
|
|
CN112300192B
(en)
*
|
2019-08-02 |
2023-08-11 |
南京长澳医药科技有限公司 |
Nitroimidazole compound, preparation method and application thereof
|
|
CN110483549B
(en)
*
|
2019-08-30 |
2021-03-05 |
沈阳药科大学 |
Preparation method of nitroimidazole pyran antituberculosis drug
|
|
CN110615800A
(en)
*
|
2019-10-16 |
2019-12-27 |
李丽丽 |
Nitroimidazole compound and preparation method and application thereof
|
|
CN112156088B
(en)
*
|
2020-10-30 |
2021-08-31 |
健民药业集团股份有限公司 |
Application of compound in preparation of mycobacterium tuberculosis inhibitor
|
|
CN113603706A
(en)
*
|
2021-08-04 |
2021-11-05 |
深圳市泰力生物医药有限公司 |
Crystal form of delamasil, active drug and pharmaceutical composition containing the crystal form
|
|
JPWO2024024938A1
(en)
|
2022-07-29 |
2024-02-01 |
|
|
|
CN115368252B
(en)
*
|
2022-09-19 |
2024-01-12 |
西北农林科技大学 |
A 4-aminophenol derivative and its application
|
|
CN116640106B
(en)
*
|
2023-05-11 |
2024-03-08 |
郑州大学 |
A kind of phenylpiperazine compound and its preparation method and application
|
|
CN119059990B
(en)
*
|
2024-11-01 |
2025-02-07 |
安徽昊帆生物有限公司 |
Preparation method of 1-carbamic acid tert-butyl piperazine
|