AU8790591A - Complexes containing s(+) phenyl alkane acids and alpha-amino acids - Google Patents
Complexes containing s(+) phenyl alkane acids and alpha-amino acidsInfo
- Publication number
- AU8790591A AU8790591A AU87905/91A AU8790591A AU8790591A AU 8790591 A AU8790591 A AU 8790591A AU 87905/91 A AU87905/91 A AU 87905/91A AU 8790591 A AU8790591 A AU 8790591A AU 8790591 A AU8790591 A AU 8790591A
- Authority
- AU
- Australia
- Prior art keywords
- acids
- alpha
- amino acids
- complexes containing
- phenyl alkane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001371 alpha-amino acids Chemical class 0.000 title 1
- 235000008206 alpha-amino acids Nutrition 0.000 title 1
- -1 phenyl alkane acids Chemical class 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- HEFNNWSXXWATRW-JTQLQIEISA-N dexibuprofen Chemical compound CC(C)CC1=CC=C([C@H](C)C(O)=O)C=C1 HEFNNWSXXWATRW-JTQLQIEISA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Novel complexes of S-(+)-ibuprofen and amino acids are described. These complexes have anti-inflammatory, antipyretic and antimicrobial properties and also analgesic effects. <IMAGE>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4036458 | 1990-11-15 | ||
| DE4036458 | 1990-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU8790591A true AU8790591A (en) | 1992-05-21 |
Family
ID=6418339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU87905/91A Abandoned AU8790591A (en) | 1990-11-15 | 1991-11-15 | Complexes containing s(+) phenyl alkane acids and alpha-amino acids |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0486045B1 (en) |
| JP (1) | JPH0656737A (en) |
| KR (1) | KR920009774A (en) |
| CN (1) | CN1061404A (en) |
| AT (1) | ATE137733T1 (en) |
| AU (1) | AU8790591A (en) |
| BG (1) | BG95490A (en) |
| BR (1) | BR9104996A (en) |
| CA (1) | CA2055683A1 (en) |
| CS (1) | CS346491A3 (en) |
| DE (2) | DE4137675A1 (en) |
| HU (1) | HUT59656A (en) |
| MX (1) | MX9102088A (en) |
| NZ (1) | NZ240617A (en) |
| PL (1) | PL292413A1 (en) |
| ZA (1) | ZA919077B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU642309B2 (en) * | 1990-11-15 | 1993-10-14 | Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg | Complexes containing S(+) phenyl alkane acids and amino sugars |
| AU643168B2 (en) * | 1990-11-15 | 1993-11-04 | Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg | Complexes containing S(+)-phenyl alkane acids and alpha-hydroxyalkane acids |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992017185A1 (en) * | 1991-03-29 | 1992-10-15 | University Of Florida | Targeted drug delivery via mixed phosphate derivatives |
| ES2100037T3 (en) * | 1992-12-02 | 1997-06-01 | Knoll Ag | PROCESS TO PREPARE SUBSTANTIALLY PURE ENANTIOMERS OF PHENYLPROPIONIC ACIDS. |
| IT1272149B (en) * | 1993-03-26 | 1997-06-11 | Zambon Spa | PHARMECEUTICAL COMPOSITION WITH ANALGESIC ACTIVITY |
| IT1264855B1 (en) * | 1993-06-21 | 1996-10-17 | Zambon Spa | PHARMACEUTICAL COMPOSITIONS CONTAINING S (+) - 2- (4-ISOBUTYLPHENYL) PROPIONIC ACID SALTS WITH BASIC AMINO ACIDS |
| CN1303991C (en) * | 1998-05-15 | 2007-03-14 | 沃尼尔·朗伯公司 | Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivative process for preparing the same |
| AR057882A1 (en) | 2005-11-09 | 2007-12-26 | Novartis Ag | DOUBLE ACTION COMPOUNDS OF ANGIOTENSIN RECEPTOR BLOCKERS AND NEUTRAL ENDOPEPTIDASE INHIBITORS |
| CN101455653B (en) * | 2007-12-13 | 2013-03-06 | 天津医科大学 | Arginine ibuprofen oral disintegrating tablets and preparation method thereof |
| CN116621689A (en) * | 2023-04-24 | 2023-08-22 | 山东省药学科学院 | L-lysine-biphenyl acetate, and preparation method and application thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1497044A (en) * | 1974-03-07 | 1978-01-05 | Prodotti Antibiotici Spa | Salts of phenyl-alkanoic acids |
| ES2055685T3 (en) * | 1986-11-14 | 1994-09-01 | Puetter Medice Chem Pharm | PROCEDURE FOR OBTAINING A MEDICINAL PRODUCT CONTAINING IBUPROFEN. |
| PT95564B (en) * | 1989-10-17 | 1997-11-28 | Merck & Co Inc | PROCESS FOR THE PREPARATION OF UTEIS (+) - IBUPROFEN-D-AMINOACIDES AS INTENSIFIED ACCELERATED ATTACK ANALGESICS |
-
1991
- 1991-11-14 HU HU913571A patent/HUT59656A/en unknown
- 1991-11-15 AU AU87905/91A patent/AU8790591A/en not_active Abandoned
- 1991-11-15 BG BG095490A patent/BG95490A/en unknown
- 1991-11-15 MX MX9102088A patent/MX9102088A/en unknown
- 1991-11-15 CS CS913464A patent/CS346491A3/en unknown
- 1991-11-15 CA CA002055683A patent/CA2055683A1/en not_active Abandoned
- 1991-11-15 JP JP3354099A patent/JPH0656737A/en active Pending
- 1991-11-15 EP EP91119522A patent/EP0486045B1/en not_active Revoked
- 1991-11-15 DE DE4137675A patent/DE4137675A1/en not_active Withdrawn
- 1991-11-15 PL PL29241391A patent/PL292413A1/en unknown
- 1991-11-15 KR KR1019910020368A patent/KR920009774A/en not_active Withdrawn
- 1991-11-15 NZ NZ240617A patent/NZ240617A/en unknown
- 1991-11-15 DE DE59107790T patent/DE59107790D1/en not_active Revoked
- 1991-11-15 CN CN91110739A patent/CN1061404A/en active Pending
- 1991-11-15 ZA ZA919077A patent/ZA919077B/en unknown
- 1991-11-15 AT AT91119522T patent/ATE137733T1/en not_active IP Right Cessation
- 1991-11-18 BR BR919104996A patent/BR9104996A/en not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU642309B2 (en) * | 1990-11-15 | 1993-10-14 | Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg | Complexes containing S(+) phenyl alkane acids and amino sugars |
| AU643168B2 (en) * | 1990-11-15 | 1993-11-04 | Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg | Complexes containing S(+)-phenyl alkane acids and alpha-hydroxyalkane acids |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0486045A2 (en) | 1992-05-20 |
| CN1061404A (en) | 1992-05-27 |
| PL292413A1 (en) | 1993-01-25 |
| ZA919077B (en) | 1992-08-26 |
| ATE137733T1 (en) | 1996-05-15 |
| JPH0656737A (en) | 1994-03-01 |
| DE59107790D1 (en) | 1996-06-13 |
| BR9104996A (en) | 1992-06-23 |
| HU913571D0 (en) | 1992-01-28 |
| CA2055683A1 (en) | 1992-05-16 |
| BG95490A (en) | 1993-12-24 |
| NZ240617A (en) | 1994-12-22 |
| EP0486045B1 (en) | 1996-05-08 |
| CS346491A3 (en) | 1992-06-17 |
| KR920009774A (en) | 1992-06-25 |
| EP0486045A3 (en) | 1992-12-09 |
| HUT59656A (en) | 1992-06-29 |
| MX9102088A (en) | 1993-01-01 |
| DE4137675A1 (en) | 1992-05-21 |
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