AU8768098A - Method of treating disease using a tocotrienol and alpha-lipoic acid r derivatives or an ester thereof - Google Patents
Method of treating disease using a tocotrienol and alpha-lipoic acid r derivatives or an ester thereofInfo
- Publication number
- AU8768098A AU8768098A AU87680/98A AU8768098A AU8768098A AU 8768098 A AU8768098 A AU 8768098A AU 87680/98 A AU87680/98 A AU 87680/98A AU 8768098 A AU8768098 A AU 8768098A AU 8768098 A AU8768098 A AU 8768098A
- Authority
- AU
- Australia
- Prior art keywords
- tocotrienol
- alpha
- derivatives
- ester
- lipoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 title 2
- GJJVAFUKOBZPCB-UHFFFAOYSA-N 2-methyl-2-(4,8,12-trimethyltrideca-3,7,11-trienyl)-3,4-dihydrochromen-6-ol Chemical compound OC1=CC=C2OC(CCC=C(C)CCC=C(C)CCC=C(C)C)(C)CCC2=C1 GJJVAFUKOBZPCB-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 235000019136 lipoic acid Nutrition 0.000 title 1
- 229960002663 thioctic acid Drugs 0.000 title 1
- 229930003802 tocotrienol Natural products 0.000 title 1
- 239000011731 tocotrienol Substances 0.000 title 1
- 235000019148 tocotrienols Nutrition 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5543397P | 1997-08-04 | 1997-08-04 | |
| US60055433 | 1997-08-04 | ||
| PCT/US1998/016207 WO1999006040A1 (en) | 1997-08-04 | 1998-08-04 | Method of treating disease using a tocotrienol and alpha-lipoic acid or derivatives or an ester thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU8768098A true AU8768098A (en) | 1999-02-22 |
Family
ID=21997763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU87680/98A Abandoned AU8768098A (en) | 1997-08-04 | 1998-08-04 | Method of treating disease using a tocotrienol and alpha-lipoic acid r derivatives or an ester thereof |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU8768098A (en) |
| WO (1) | WO1999006040A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2786104B1 (en) | 1998-11-25 | 2002-12-27 | Centre Nat Rech Scient | INHIBITORS OF NF-KB ACTIVATION, AND THEIR PHARMACEUTICAL USES |
| US6284786B1 (en) * | 1999-02-16 | 2001-09-04 | The Center For The Improvement Of Human Functioning, Int'l., Inc. | Treatment of cancer using lipoic acid in combination with ascorbic acid |
| FR2791571B1 (en) * | 1999-04-02 | 2002-10-04 | Sod Conseils Rech Applic | ASSOCIATION OF NO SYNTHASE INHIBITOR (S) AND METABOLIC ANTIOXIDANT (S) |
| IT1312060B1 (en) * | 1999-04-09 | 2002-04-04 | Antibioticos Spa | USE OF ALPHA LIPOIC ACID IN ANTIMETASTATIC TREATMENT. |
| WO2000078296A2 (en) * | 1999-06-17 | 2000-12-28 | Basf Aktiengesellschaft | Tocotrienol and/or tocotrienol derivatives for the treatment or prophylaxis of glutamate- and/or calcium-induced disorders |
| DE19941217A1 (en) * | 1999-08-30 | 2001-03-15 | Asta Medica Ag | Treatment of migraines by administration of alpha-lipoic acid or derivatives thereof |
| JP2001342133A (en) * | 2000-03-31 | 2001-12-11 | Eisai Co Ltd | gamma-TOCOTRIENOL-CONTAINING DIURETIC |
| EP1270004B1 (en) * | 2000-03-31 | 2010-06-09 | Eisai R&D Management Co., Ltd. | Use of gamma-tocotrienol as diuretic |
| DE10027968A1 (en) * | 2000-06-08 | 2001-12-13 | Asta Medica Ag | Adjuvant therapy of dementia using alpha-lipoic acid or derivative, is effective in combination with antidementia or neurotransmission improving agents in improving cognitive function in e.g. Alzheimer's disease patients |
| DE20203244U1 (en) | 2002-03-01 | 2002-05-23 | Meins, Wolfgang, Prof. Dr., 22391 Hamburg | Pharmaceutical composition for the prevention of Alzheimer's dementia |
| US20040034093A1 (en) * | 2002-05-30 | 2004-02-19 | Hensley Kenneth L. | Methods for enhancing motor performance and/or endurance |
| RU2325908C1 (en) * | 2006-09-20 | 2008-06-10 | Государственное учреждение научно-исследовательский институт онкологии Томского Научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ онкологии ТНЦ СО РАМН) | Method of complication prevention accompanying combinatorial treatment of lung and venter cancer |
| DE102007038849A1 (en) | 2007-08-16 | 2009-02-19 | Adscil Gmbh | Use of R (+) - alpha lipoic acid for the treatment of cryptogenic neuropathy |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5217992A (en) * | 1989-10-04 | 1993-06-08 | Bristol-Myers Squibb Company | Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders |
| WO1993009777A1 (en) * | 1991-11-22 | 1993-05-27 | Lipogenics, Inc. | Tocotrienols and tocotrienol-like compounds and methods for their use |
-
1998
- 1998-08-04 AU AU87680/98A patent/AU8768098A/en not_active Abandoned
- 1998-08-04 WO PCT/US1998/016207 patent/WO1999006040A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999006040A1 (en) | 1999-02-11 |
| WO1999006040A9 (en) | 1999-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |