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AU8600691A - Ergoline derivatives useful as dopamine antagonistic agents - Google Patents

Ergoline derivatives useful as dopamine antagonistic agents

Info

Publication number
AU8600691A
AU8600691A AU86006/91A AU8600691A AU8600691A AU 8600691 A AU8600691 A AU 8600691A AU 86006/91 A AU86006/91 A AU 86006/91A AU 8600691 A AU8600691 A AU 8600691A AU 8600691 A AU8600691 A AU 8600691A
Authority
AU
Australia
Prior art keywords
derivatives useful
ergoline derivatives
antagonistic agents
dopamine antagonistic
dopamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU86006/91A
Other versions
AU638874B2 (en
Inventor
Rene Amstutz
Rudolf Markstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of AU8600691A publication Critical patent/AU8600691A/en
Application granted granted Critical
Publication of AU638874B2 publication Critical patent/AU638874B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Electromagnets (AREA)
  • Fixed Capacitors And Capacitor Manufacturing Machines (AREA)
  • Soft Magnetic Materials (AREA)

Abstract

Ergoline derivatives of the formula I <IMAGE> in which R1, R2 and R3 are as defined in the description, their preparation and use as therapeutics.
AU86006/91A 1990-10-20 1991-10-18 Ergoline derivatives useful as dopamine antagonistic agents Ceased AU638874B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4033496 1990-10-20
DE4033496A DE4033496A1 (en) 1990-10-20 1990-10-20 NEW ERGOL DERIVATIVES, THEIR PRODUCTION AND USE

Publications (2)

Publication Number Publication Date
AU8600691A true AU8600691A (en) 1992-04-30
AU638874B2 AU638874B2 (en) 1993-07-08

Family

ID=6416775

Family Applications (1)

Application Number Title Priority Date Filing Date
AU86006/91A Ceased AU638874B2 (en) 1990-10-20 1991-10-18 Ergoline derivatives useful as dopamine antagonistic agents

Country Status (20)

Country Link
EP (1) EP0483063B1 (en)
JP (1) JPH04257583A (en)
KR (1) KR920008038A (en)
AT (1) ATE111099T1 (en)
AU (1) AU638874B2 (en)
CA (1) CA2053712A1 (en)
CZ (1) CZ279954B6 (en)
DE (2) DE4033496A1 (en)
DK (1) DK0483063T3 (en)
ES (1) ES2059097T3 (en)
FI (1) FI914942A7 (en)
HU (1) HU210805B (en)
IE (1) IE913663A1 (en)
IL (1) IL99782A (en)
MX (1) MX9101659A (en)
MY (1) MY131110A (en)
NZ (1) NZ240280A (en)
PT (1) PT99286A (en)
RO (1) RO106992B1 (en)
ZA (1) ZA918346B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110071014A (en) 2008-10-17 2011-06-27 위스콘신 얼럼나이 리서어치 화운데이션 Method for preparing biologically active alpha-beta peptide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517972A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-cyanomethylergoline i
AR223177A1 (en) * 1978-05-23 1981-07-31 Lilly Industries Ltd PROCEDURE FOR PREPARING INDOLO-ISOQUINOLINE DERIVATIVES
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
GB8702364D0 (en) * 1987-02-03 1987-03-11 Erba Farmitalia Ergolinyl heterocycles
HUT51275A (en) * 1988-01-26 1990-04-28 Sandoz Ag Process for producing ergolin derivatives and pharmaceutical compositions containing them
DK0464178T3 (en) * 1990-01-25 1996-01-02 Pharmacia Spa Process for the preparation of ergoline derivatives

Also Published As

Publication number Publication date
IE913663A1 (en) 1992-04-22
DE4033496A1 (en) 1992-04-23
HUT60495A (en) 1992-09-28
EP0483063B1 (en) 1994-09-07
CS315391A3 (en) 1992-05-13
ZA918346B (en) 1993-04-19
NZ240280A (en) 1993-09-27
DK0483063T3 (en) 1994-11-14
DE59102829D1 (en) 1994-10-13
EP0483063A1 (en) 1992-04-29
FI914942L (en) 1992-04-21
RO106992B1 (en) 1993-08-30
ES2059097T3 (en) 1994-11-01
AU638874B2 (en) 1993-07-08
FI914942A0 (en) 1991-10-18
ATE111099T1 (en) 1994-09-15
FI914942A7 (en) 1992-04-21
MY131110A (en) 2007-07-31
IL99782A (en) 1995-05-26
HU913212D0 (en) 1992-01-28
KR920008038A (en) 1992-05-27
MX9101659A (en) 1994-01-31
PT99286A (en) 1992-08-31
CA2053712A1 (en) 1992-04-21
JPH04257583A (en) 1992-09-11
HU210805B (en) 1995-07-28
IL99782A0 (en) 1992-08-18
CZ279954B6 (en) 1995-09-13

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