AU8512598A - Oligonuclotides having 3' terminal stereospecific phosphorothioates - Google Patents

Oligonuclotides having 3' terminal stereospecific phosphorothioates

Info

Publication number: AU8512598A
Authority: AU; Australia
Prior art keywords: oligonuclotides; stereospecific; phosphorothioates; terminal; terminal stereospecific
Prior art date: 1997-07-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU85125/98A

Inventor

Aharon S Cohen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aceragen Inc

Original Assignee

Hybridon Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-25

Filing date

1998-07-24

Publication date

1999-02-16

1998-07-24 Application filed by Hybridon Inc filed Critical Hybridon Inc

1999-02-16 Publication of AU8512598A publication Critical patent/AU8512598A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AU85125/98A 1997-07-25 1998-07-24 Oligonuclotides having 3' terminal stereospecific phosphorothioates Abandoned AU8512598A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US5371897P	1997-07-25	1997-07-25
US60053718		1997-07-25
PCT/US1998/015420 WO1999005160A2 (en)	1997-07-25	1998-07-24	Oligonuclotides having 3' terminal stereospecific phosphorothioates

Publications (1)

Publication Number	Publication Date
AU8512598A true AU8512598A (en)	1999-02-16

Family

ID=21986075

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU85125/98A Abandoned AU8512598A (en)	1997-07-25	1998-07-24	Oligonuclotides having 3' terminal stereospecific phosphorothioates

Country Status (2)

Country	Link
AU (1)	AU8512598A (en)
WO (1)	WO1999005160A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6242589B1 (en)	1998-07-14	2001-06-05	Isis Pharmaceuticals, Inc.	Phosphorothioate oligonucleotides having modified internucleoside linkages
US6867294B1 (en)	1998-07-14	2005-03-15	Isis Pharmaceuticals, Inc.	Gapped oligomers having site specific chiral phosphorothioate internucleoside linkages
EP2370451B1 (en)	2008-12-02	2016-11-16	Wave Life Sciences Japan, Inc.	Method for the synthesis of phosphorus atom modified nucleic acids
KR101885383B1 (en)	2009-07-06	2018-08-03	웨이브 라이프 사이언시스 리미티드	Novel nucleic acid prodrugs and methods of use thereof
US10428019B2 (en)	2010-09-24	2019-10-01	Wave Life Sciences Ltd.	Chiral auxiliaries
EP2734208B1 (en)	2011-07-19	2017-03-01	Wave Life Sciences Ltd.	Methods for the synthesis of functionalized nucleic acids
PL2872485T3 (en)	2012-07-13	2021-05-31	Wave Life Sciences Ltd.	Asymmetric auxiliary group
CN104661664B (en)	2012-07-13	2020-07-03	波涛生命科学有限公司	Chiral control
CA2879066C (en)	2012-07-13	2019-08-13	Shin Nippon Biomedical Laboratories, Ltd.	Chiral nucleic acid adjuvant
WO2015108047A1 (en)	2014-01-15	2015-07-23	株式会社新日本科学	Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator
JPWO2015108046A1 (en)	2014-01-15	2017-03-23	株式会社新日本科学	Chiral nucleic acid adjuvant and antiallergic agent having antiallergic action
JPWO2015108048A1 (en)	2014-01-15	2017-03-23	株式会社新日本科学	Chiral nucleic acid adjuvant and antitumor agent having antitumor activity
EP4137572A1 (en)	2014-01-16	2023-02-22	Wave Life Sciences Ltd.	Chiral design
MA43072A (en)	2015-07-22	2018-05-30	Wave Life Sciences Ltd	COMPOSITIONS OF OLIGONUCLEOTIDES AND RELATED PROCESSES

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4521509A (en) *	1982-11-24	1985-06-04	Research Corporation	Method for degrading DNA
US4924624A (en) *	1987-10-22	1990-05-15	Temple University-Of The Commonwealth System Of Higher Education	2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof
WO1989005358A1 (en) *	1987-11-30	1989-06-15	University Of Iowa Research Foundation	Dna and rna molecules stabilized by modifications of the 3'-terminal phosphodiester linkage and their use as nucleic acid probes and as therapeutic agents to block the expression of specifically targeted genes
JP2693643B2 (en) *	1991-10-15	1997-12-24	アイシス・ファーマシューティカルス・インコーポレーテッド	Oligonucleotide with chiral phosphorus bond
CA2208528A1 (en) *	1994-12-22	1996-06-27	Hybridon, Inc.	Synthesis of stereospecific oligonucleotide phosphorothioates
JPH10510433A (en) *	1995-06-06	1998-10-13	アイシス・ファーマシューティカルス・インコーポレーテッド	Oligonucleotides with high chiral purity phosphorothioate linkages

1998
- 1998-07-24 WO PCT/US1998/015420 patent/WO1999005160A2/en not_active Ceased
- 1998-07-24 AU AU85125/98A patent/AU8512598A/en not_active Abandoned

Also Published As

Publication number	Publication date
WO1999005160A3 (en)	1999-04-08
WO1999005160A2 (en)	1999-02-04

Publication	Publication Date	Title
EP0676828A3 (en)	1998-03-18	Connector
AU3303595A (en)	1996-04-26	Capillary connector
AU5773198A (en)	1998-08-26	Can ends
AU6936098A (en)	1998-10-30	Connector
AU8512598A (en)	1999-02-16	Oligonuclotides having 3' terminal stereospecific phosphorothioates
AU5670498A (en)	1998-08-03	Connector
AU4101097A (en)	1998-04-23	Offset connector
AU7059298A (en)	1998-11-11	Can end
AU7170798A (en)	1998-11-24	Antithrombotic agents
AU6525998A (en)	1998-10-22	Improved metallo-endopeptidases
AU1346199A (en)	1999-06-28	Connector
AU2969997A (en)	1998-01-05	Connector
AU1870897A (en)	1998-01-21	Connector
AU718511C (en)	2002-07-25	Glyphosate liquid formulations
DE69908936D1 (en)	2003-07-24	2''-deoxyhygromycinderivate
AU7274098A (en)	1998-11-24	Antithrombotic agents
AU2049997A (en)	1998-08-07	Enhanced flavors using 2'-hydroxypropiophenone
AU7170898A (en)	1998-11-24	Antithrombotic agents
AU7563598A (en)	1998-11-24	Antithrombotic agents
AUPO699597A0 (en)	1997-06-19	Hill's adapta-line
GB9621627D0 (en)	1996-12-11	User 'tuneable' Skibob
AUPO782497A0 (en)	1997-07-31	Dagianda project 3 fouroctagonal
AUPP232098A0 (en)	1998-04-09	Sensacam 101
AUPP662198A0 (en)	1998-11-12	Stripakote 2000
AUPO482697A0 (en)	1997-02-20	The "Ad-light"

Legal Events

Date	Code	Title	Description
2000-04-13	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase