[go: up one dir, main page]

AU8190887A - Novel prostacyclines - Google Patents

Novel prostacyclines

Info

Publication number
AU8190887A
AU8190887A AU81908/87A AU8190887A AU8190887A AU 8190887 A AU8190887 A AU 8190887A AU 81908/87 A AU81908/87 A AU 81908/87A AU 8190887 A AU8190887 A AU 8190887A AU 8190887 A AU8190887 A AU 8190887A
Authority
AU
Australia
Prior art keywords
prostacyclines
novel
novel prostacyclines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU81908/87A
Other versions
AU604792B2 (en
Inventor
George William Holland
Ferdinand Lee
Hans Maag
Perry Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU8190887A publication Critical patent/AU8190887A/en
Application granted granted Critical
Publication of AU604792B2 publication Critical patent/AU604792B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018Esters of cycloaliphatic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
AU81908/87A 1986-12-01 1987-11-30 Novel prostacyclines Expired - Fee Related AU604792B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/936,569 US4808734A (en) 1986-12-01 1986-12-01 16-cycloalkyl-7-fluoro-prostacyclins
US936569 1998-08-28

Publications (2)

Publication Number Publication Date
AU8190887A true AU8190887A (en) 1988-06-02
AU604792B2 AU604792B2 (en) 1991-01-03

Family

ID=25468824

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81908/87A Expired - Fee Related AU604792B2 (en) 1986-12-01 1987-11-30 Novel prostacyclines

Country Status (15)

Country Link
US (1) US4808734A (en)
JP (1) JPS63145276A (en)
AT (1) AT392071B (en)
AU (1) AU604792B2 (en)
BE (1) BE1001109A3 (en)
CH (1) CH673650A5 (en)
DE (1) DE3740596A1 (en)
DK (1) DK627887A (en)
FR (1) FR2607500A1 (en)
GB (1) GB2198131B (en)
IT (1) IT1223391B (en)
NL (1) NL8702881A (en)
NZ (1) NZ222724A (en)
SE (1) SE8704771L (en)
ZA (1) ZA878946B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW208001B (en) * 1990-09-07 1993-06-21 Asahi Glass Co Ltd

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513913A (en) * 1975-06-20 1978-06-14 Ici Ltd Prostane derivatives
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
DE3176313D1 (en) * 1980-12-09 1987-08-20 Teijin Ltd Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (en) * 1981-03-11 1985-03-29 Hoffmann La Roche FLUORPROSTACYCLINE.
JPS58150583A (en) * 1982-03-04 1983-09-07 Teijin Ltd Novel halogenated prostacyclins, their preparations, and pharmaceutical compositions comprising them as active ingredients
JPS59227888A (en) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd Production of 7-fluoroprostaglandin
HU191264B (en) * 1984-01-13 1987-01-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for production of derivatives of 7-oxo-prostacyclin with selective biological effect
JPS60243079A (en) * 1984-05-18 1985-12-03 Asahi Glass Co Ltd 7-fluoroprostaglandin i2 and drug comprising it as active ingredient
US4616034A (en) * 1985-02-28 1986-10-07 G. D. Searle & Co. 15(R)-5-fluoroprostacyclins, pharmaceutical compositions and anti-thrombotic method of use thereof
JPS61289034A (en) * 1985-06-17 1986-12-19 Teijin Ltd Fatty emulsion of prostaglandin i2
FR2583828B1 (en) * 1985-06-21 1987-08-14 Kley France Sa MOTOR APPARATUS OPERATING BY SUCCESSIVE RESUMPTIONS
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds

Also Published As

Publication number Publication date
AU604792B2 (en) 1991-01-03
IT1223391B (en) 1990-09-19
AT392071B (en) 1991-01-25
CH673650A5 (en) 1990-03-30
GB2198131B (en) 1990-08-08
DK627887A (en) 1988-06-02
DK627887D0 (en) 1987-11-30
NL8702881A (en) 1988-07-01
GB2198131A (en) 1988-06-08
FR2607500A1 (en) 1988-06-03
NZ222724A (en) 1990-11-27
GB8727992D0 (en) 1988-01-06
ATA313787A (en) 1990-07-15
US4808734A (en) 1989-02-28
IT8722815A0 (en) 1987-11-30
JPS63145276A (en) 1988-06-17
DE3740596A1 (en) 1988-06-16
SE8704771D0 (en) 1987-11-30
BE1001109A3 (en) 1989-07-18
SE8704771L (en) 1988-06-02
ZA878946B (en) 1988-06-01

Similar Documents

Publication Publication Date Title
AU591007B2 (en) 3-aryloxy-3-substituted propanamines
AU7310987A (en) 1-aralkyl-4-cyano-pyrazoles
AU7270487A (en) Novel combination
AU593093B2 (en) Radio-direction-finding
AU7024087A (en) Groundsheet
AU7553887A (en) 7-acyloxy-6-aminoacyloxypolyoxylabdanes
AU6925587A (en) Naphthothiazepinones
AU8063287A (en) Triazolo-pyrimidine-2-sulphonamides
AU5988990A (en) 3-alkoxy-2-aminopropylamides
AU7372487A (en) Fire-lighters
AU7686987A (en) Triazolo-pryimidine-2-sulphonamides
AU7562487A (en) Dartboards
AU6876687A (en) Theft-deterring label-holders
AU579047B2 (en) Pyridopyrimidinediones
AU626472B2 (en) 1-n-dodecylazacycloheptane-2-thione
AU7182187A (en) 3-carbamoyl-4-hydroxy-coumarins
AU7794687A (en) Novel 4-methylphthalimides
AU7432087A (en) Roller-ski
AU6791287A (en) Sky-light
AU7769287A (en) 2-oxo-4-carboxy-pyrimidines
AU7725887A (en) 5-substituted-3-phenyl-3-(1h-imidazoyl-1-ylmethyl)-2-methyl- isoxazolidines
AU6804587A (en) 4-aminomethyl-fluoresceins
AU7594487A (en) Decahydronaphth-2-yl-alkylamines
AU8187487A (en) 1-aryloxy-3-amino-2-propanols
AU592423B2 (en) Pyridylthio-acylanilides