AU8162898A - Angiogenic modulation by notch signal transduction - Google Patents

Angiogenic modulation by notch signal transduction

Info

Publication number: AU8162898A
Authority: AU; Australia
Prior art keywords: signal transduction; notch signal; angiogenic; modulation; angiogenic modulation
Prior art date: 1997-06-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU81628/98A

Inventor

Jan Kitajewski

Hendrik Uyttendaele

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Columbia University in the City of New York

Original Assignee

Columbia University in the City of New York

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-18

Filing date

1998-06-18

Publication date

1999-01-04

1998-06-18 Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York

1999-01-04 Publication of AU8162898A publication Critical patent/AU8162898A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Cell Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AU81628/98A 1997-06-18 1998-06-18 Angiogenic modulation by notch signal transduction Abandoned AU8162898A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US87835197A	1997-06-18	1997-06-18
US08878351		1997-06-18
PCT/US1998/013050 WO1998057621A1 (en)	1997-06-18	1998-06-18	Angiogenic modulation by notch signal transduction

Publications (1)

Publication Number	Publication Date
AU8162898A true AU8162898A (en)	1999-01-04

Family

ID=25371857

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU81628/98A Abandoned AU8162898A (en)	1997-06-18	1998-06-18	Angiogenic modulation by notch signal transduction

Country Status (2)

Country	Link
AU (1)	AU8162898A (en)
WO (1)	WO1998057621A1 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9912132D0 (en) *	1999-05-26	1999-07-28	Univ Manchester	Notch regulator-related gene and uses thereof
GB0013212D0 (en) *	2000-05-31	2000-07-19	Schizophrenia Ass Of Great Bri	Notch 4 and schizophrenia
AU2008200135B2 (en) *	2000-08-03	2012-06-14	Regents Of The University Of Michigan	Isolation and use of solid tumor stem cells
US6984522B2 (en) *	2000-08-03	2006-01-10	Regents Of The University Of Michigan	Isolation and use of solid tumor stem cells
AU2002364537A1 (en) *	2001-12-07	2003-06-23	Regents Of The University Of Michigan	Prospective identification and characterization of breast cancer stem cells
US20040077569A1 (en) *	2002-10-16	2004-04-22	Isis Pharmaceuticals Inc.	Antisense modulation of Notch (Drosophila) homolog 4 expression
WO2006085224A2 (en) *	2005-02-07	2006-08-17	Karolinska Innovations Ab	Modulation of cellular hypoxia responses through notch signalling
WO2007133250A2 (en)	2005-10-31	2007-11-22	Austin Gurney	Compositions and methods for diagnosing and treating cancer
US7723477B2 (en)	2005-10-31	2010-05-25	Oncomed Pharmaceuticals, Inc.	Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
PL2032166T3 (en)	2006-06-13	2013-09-30	Oncomed Pharm Inc	Compositions and methods for diagnosing and treating cancer
US7750124B2 (en)	2006-09-29	2010-07-06	Oncomed Pharmaceuticals, Inc.	Anti-human DLL4 antibodies and compositions
AU2008209482B2 (en)	2007-01-24	2014-05-01	Oncomed Pharmaceuticals, Inc.	Compositions and methods for diagnosing and treating cancer
EP2134356A2 (en) *	2007-03-05	2009-12-23	Board of Regents, The University of Texas System	Negative genetic regulation of cancer cell renewal in synergy with notch- or numb-specific immunotherapy
NZ590127A (en)	2008-07-08	2012-11-30	Oncomed Pharm Inc	Notch1 receptor binding agents and methods of use thereof
US9132189B2 (en)	2008-07-08	2015-09-15	Oncomed Pharmaceuticals, Inc.	Notch1 binding agents and methods of use thereof
NZ592338A (en)	2008-09-26	2012-11-30	Oncomed Pharm Inc	Frizzled-binding agents and uses thereof
JP2010214019A (en) *	2009-03-18	2010-09-30	Chiba Univ	Ischemic tissue regeneration method using notch signal
US8883145B2 (en)	2009-10-16	2014-11-11	Oncomed Pharmaceuticals, Inc.	Methods of treatment with DLL4 antagonists and an anti-hypertensive agent
TWI535445B (en)	2010-01-12	2016-06-01	安可美德藥物股份有限公司	Wnt antagonists and methods of treatment and screening
AU2011205316B2 (en)	2010-01-13	2015-05-28	Oncomed Pharmaceuticals, Inc.	Notch1 binding agents and methods of use thereof
CA2794674A1 (en)	2010-04-01	2011-10-06	Oncomed Pharmaceuticals, Inc.	Frizzled-binding agents and uses thereof
US8551479B2 (en)	2010-09-10	2013-10-08	Oncomed Pharmaceuticals, Inc.	Methods for treating melanoma
LT3485903T (en)	2011-09-23	2023-02-27	Mereo Biopharma 5, Inc.	Vegf/dll4 binding agents and uses thereof
JP2015536933A (en)	2012-10-23	2015-12-24	オンコメッドファーマシューティカルズインコーポレイテッド	Methods of treating neuroendocrine tumors using Wnt pathway binding agents
US9599620B2 (en)	2012-10-31	2017-03-21	Oncomed Pharmaceuticals, Inc.	Methods and monitoring of treatment with a DLL4 antagonist
JP2016510411A (en)	2013-02-04	2016-04-07	オンコメッドファーマシューティカルズインコーポレイテッド	Methods and monitoring of treatment with WNT pathway inhibitors
US9168300B2 (en)	2013-03-14	2015-10-27	Oncomed Pharmaceuticals, Inc.	MET-binding agents and uses thereof
EP3212233B1 (en)	2014-10-31	2020-06-24	Oncomed Pharmaceuticals, Inc.	Combination therapy for treatment of disease
AU2016326609B2 (en)	2015-09-23	2023-03-09	Mereo Biopharma 5, Inc.	Methods and compositions for treatment of cancer
WO2024074649A1 (en) *	2022-10-05	2024-04-11	Alcea Therapeutics, Inc.	Notch4 antibodies, compositions, and methods for treating airway inflammation

1998
- 1998-06-18 AU AU81628/98A patent/AU8162898A/en not_active Abandoned
- 1998-06-18 WO PCT/US1998/013050 patent/WO1998057621A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO1998057621A1 (en)	1998-12-23

Publication	Publication Date	Title
AU8162898A (en)	1999-01-04	Angiogenic modulation by notch signal transduction
AU8687898A (en)	1999-03-01	Suture retrograder
AU1709299A (en)	1999-06-16	Mixer-injectors
AU2827897A (en)	1997-11-26	Maltodextrin-based adhesives
AU7351598A (en)	1998-11-27	Tensioner
AU1027499A (en)	1999-04-23	32P-polyphosphazene
AU5372598A (en)	1998-06-29	Tfpx synthesis
AU6827898A (en)	1998-09-29	Detergent-package combination
AU9066598A (en)	1999-03-01	Substituted 4-benzoyl-pyrazoles
AU1577999A (en)	1999-06-28	Monoski
AU3620297A (en)	1998-02-10	Substituted triazoloazinesulphonamides
AU6232198A (en)	1998-09-22	Tension member
AU4696899A (en)	2000-01-05	Modulating platelet function
AU6304698A (en)	1998-09-18	Sounder
AU3771497A (en)	1998-03-06	Substituted p-trifluoromethylphenyluracils
AU6525998A (en)	1998-10-22	Improved metallo-endopeptidases
AU2624797A (en)	1998-01-15	Balanced modulator
AU1040999A (en)	1999-05-31	Securing mechanism
AU6090898A (en)	1998-07-31	Substituted 4-benzoyl-pyrazoles
AU1526799A (en)	1999-07-05	Voltage signal modulation scheme
AU2000299A (en)	1999-07-12	Semaphorin zsmf-3
AU9552998A (en)	1999-05-24	Phase change mechanism
AU2955597A (en)	1998-01-05	Substituted phenyluracils
AU7530198A (en)	1998-11-27	Substituted 4-benzoyl-pyrazoles
AU1445597A (en)	1997-08-01	Instrument

Legal Events

Date	Code	Title	Description
2000-03-02	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase