AU8016894A - Betaglycan polypeptides having tgf-beta binding activity - Google Patents

Betaglycan polypeptides having tgf-beta binding activity

Info

Publication number: AU8016894A
Authority: AU; Australia
Prior art keywords: tgf; binding activity; beta binding; betaglycan polypeptides; betaglycan
Prior art date: 1993-10-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU80168/94A

Inventor

Ralf Butzow

Daikichi Fukushima

Erkki Ruoslahti

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanford Burnham Prebys Medical Discovery Institute

Original Assignee

Sanford Burnham Prebys Medical Discovery Institute

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-15

Filing date

1994-10-14

Publication date

1995-05-04

1994-10-14 Application filed by Sanford Burnham Prebys Medical Discovery Institute filed Critical Sanford Burnham Prebys Medical Discovery Institute

1995-05-04 Publication of AU8016894A publication Critical patent/AU8016894A/en

Status Abandoned legal-status Critical Current

Links

102100033663 Transforming growth factor beta receptor type 3 Human genes 0.000 title 1
108010079292 betaglycan Proteins 0.000 title 1
230000027455 binding Effects 0.000 title 1
229920001184 polypeptide Polymers 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Cell Biology (AREA)
Peptides Or Proteins (AREA)

AU80168/94A 1993-10-15 1994-10-14 Betaglycan polypeptides having tgf-beta binding activity Abandoned AU8016894A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US13836893A	1993-10-15	1993-10-15
US138368		1993-10-15
PCT/US1994/011648 WO1995010610A1 (en)	1993-10-15	1994-10-14	BETAGLYCAN POLYPEPTIDES HAVING TGF-β BINDING ACTIVITY

Publications (1)

Publication Number	Publication Date
AU8016894A true AU8016894A (en)	1995-05-04

Family

ID=22481710

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU80168/94A Abandoned AU8016894A (en)	1993-10-15	1994-10-14	Betaglycan polypeptides having tgf-beta binding activity

Country Status (2)

Country	Link
AU (1)	AU8016894A (en)
WO (1)	WO1995010610A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69332026T2 (en) *	1992-10-29	2002-10-31	Celtrix Pharmaceuticals, Inc.	TYPE II TGF-BETA BINDING RECEPTOR FRAGMENT AS A THERAPEUTIC AGENT
GB2304045A (en) *	1995-08-04	1997-03-12	Univ Manchester	Betaglycan compositions for promoting the healing of wounds and fibrotic diseases
AU777166B2 (en) *	1999-12-15	2004-10-07	Research Development Foundation	Betaglycan as an inhibin receptor and uses thereof
US20070184052A1 (en) *	2003-05-09	2007-08-09	Lin Herbert Y	Soluble tgf-b type III receptor fusion proteins
MXPA03004172A (en) *	2003-05-13	2004-11-18	Univ Mexico Nacional Autonoma	Treatment kit which assists with antibiotic therapy for intracellular infectious diseases.
WO2005097832A2 (en)	2004-03-31	2005-10-20	Genentech, Inc.	Humanized anti-tgf-beta antibodies
GB0426960D0 (en)	2004-12-08	2005-01-12	Ares Trading Sa	TGR-3 like protein receptor
JP5602365B2 (en)	2005-10-25	2014-10-08	ザ・ジョンズ・ホプキンス・ユニバーシティ	Methods and compositions for treating Marfan syndrome and related diseases.
EP1998810A4 (en)	2006-03-13	2009-09-02	Univ Johns Hopkins	INCREASE IN ENDOTHELIAL THROMBORISISTANCE
HUE035575T2 (en)	2006-10-03	2018-05-28	Genzyme Corp	Use of TGF beta antagonists to treat infants at risk of developing bronchopulmonary dysplasia
EP2660314A4 (en)	2010-12-27	2014-09-03	Lsip Llc	iPS CELLS AND METHOD FOR GENERATING SAME
EP2737083A1 (en)	2011-07-27	2014-06-04	INSERM (Institut National de la Santé et de la Recherche Scientifique)	Methods for diagnosing and treating myhre syndrome
BR112014009789A2 (en)	2011-10-26	2017-04-25	Seattle Children's Res Inst	cysteamine in the treatment of fibrotic disease
EP3553169B1 (en)	2011-12-28	2021-11-03	Kyoto Prefectural Public University Corporation	Normalization of culture of corneal endothelial cells
MX383328B (en)	2013-10-31	2025-03-13	Kyoto Prefectural Public Univ Corp	THERAPEUTIC DRUG FOR DISEASES RELATED TO CELL DEATH OF THE ENDOPLASMIC RETICULUM IN THE CORNEAL ENDOTHELIUM.
US10882903B2 (en)	2015-05-18	2021-01-05	Arizona Board Of Regents On Behalf Of The University Of Arizona	Methods and compositions for treating an alphavirus infection
WO2020201362A2 (en)	2019-04-02	2020-10-08	INSERM (Institut National de la Santé et de la Recherche Médicale)	Methods of predicting and preventing cancer in patients having premalignant lesions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993010215A1 (en) *	1991-11-15	1993-05-27	Memorial Sloan-Kettering Cancer Center	Purified proteoglycan betaglycan, compositions, and methods

1994
- 1994-10-14 AU AU80168/94A patent/AU8016894A/en not_active Abandoned
- 1994-10-14 WO PCT/US1994/011648 patent/WO1995010610A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO1995010610A1 (en)	1995-04-20

Publication	Publication Date	Title
AU1321895A (en)	1995-07-17	Binding assay
AU2662795A (en)	1996-01-04	Cdk4 binding proteins
AU4370596A (en)	1996-06-26	Novel hedgehog-derived polypeptides
AU7978694A (en)	1995-05-08	Catalytic dna
AU5283793A (en)	1994-05-09	Recombinant specific binding protein
AU2919197A (en)	1997-12-05	Flat antenna
ZA947122B (en)	1995-05-08	Drug binding protein.
AU5926194A (en)	1994-10-13	Catalyst composition
AU2527497A (en)	1997-10-22	Puzzle book
AU3216797A (en)	1998-01-07	Novel heparin binding peptides
AU8016894A (en)	1995-05-04	Betaglycan polypeptides having tgf-beta binding activity
AU1372795A (en)	1995-07-10	Catalyst composition
AU6472994A (en)	1994-12-22	Card
AU671148C (en)	1994-04-21	Binding element
AU6939594A (en)	1994-12-20	Stapler
GB9326451D0 (en)	1994-02-23	Binding assay
AU4312697A (en)	1998-05-05	Catalysts
AU5384596A (en)	1996-11-21	Binding assembly
AU1475597A (en)	1997-08-28	Rapid-freezing container
AU3640397A (en)	1998-01-05	Ob protein binding protein
AU1235597A (en)	1997-08-07	Fibrinogen binding peptides
AU8139594A (en)	1995-06-06	Microtome
AU4586497A (en)	1998-04-24	Calcium-integrin binding protein
AU2379397A (en)	1997-09-22	Container
AU2435295A (en)	1996-01-05	Binding assembly