AU778106B2 - Synthetic gene for expressing active retroviral protein in eukaryotes - Google Patents

Synthetic gene for expressing active retroviral protein in eukaryotes Download PDF

Info

Publication number: AU778106B2
Authority: AU; Australia
Prior art keywords: gene; retroviral; protein; gag; pol
Prior art date: 1999-04-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

AU45579/00A

Other languages

English (en)

Other versions

AU4557900A (en

Inventor

Peter Cherepanov

Erik De Clercq

Zeger Debyser

Wim Pluymers

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Katholieke Universiteit Leuven

Original Assignee

Katholieke Universiteit Leuven

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-26

Filing date

2000-04-26

Publication date

2004-11-18

2000-04-26 Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven

2000-11-10 Publication of AU4557900A publication Critical patent/AU4557900A/en

2004-11-18 Application granted granted Critical

2004-11-18 Publication of AU778106B2 publication Critical patent/AU778106B2/en

2020-04-26 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16051—Methods of production or purification of viral material
- C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Virology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AU45579/00A 1999-04-26 2000-04-26 Synthetic gene for expressing active retroviral protein in eukaryotes Ceased AU778106B2 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
EP99201306		1999-04-26
EP99201306		1999-04-26
EP00200171		2000-01-18
EP00200171		2000-01-18
PCT/EP2000/003765 WO2000065076A2 (fr)	1999-04-26	2000-04-26	Gene synthetique destine a l'expression d'une proteine retrovirale active dans les eucariotes

Publications (2)

Publication Number	Publication Date
AU4557900A AU4557900A (en)	2000-11-10
AU778106B2 true AU778106B2 (en)	2004-11-18

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Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU45579/00A Ceased AU778106B2 (en)	1999-04-26	2000-04-26	Synthetic gene for expressing active retroviral protein in eukaryotes

Country Status (11)

Country	Link
EP (1)	EP1183381A2 (fr)
JP (1)	JP2002542791A (fr)
AU (1)	AU778106B2 (fr)
BR (1)	BR0010077A (fr)
CA (1)	CA2369058A1 (fr)
HU (1)	HUP0201019A2 (fr)
IL (1)	IL146090A0 (fr)
NO (1)	NO20015168L (fr)
PL (1)	PL351988A1 (fr)
RU (1)	RU2001131728A (fr)
WO (1)	WO2000065076A2 (fr)

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GB9803351D0 (en)	1998-02-17	1998-04-15	Oxford Biomedica Ltd	Anti-viral vectors
WO2000039304A2 (fr)	1998-12-31	2000-07-06	Chiron Corporation	Polynucleotides codant pour des polypeptides antigeniques du type c du vih; polypeptides et leurs utilisations
EP1141313A2 (fr)	1998-12-31	2001-10-10	Chiron Corporation	Expression amelioree de polypeptides hiv et production de particules de type viral
US6656706B2 (en) *	1999-12-23	2003-12-02	The United States Of America As Represented By The Department Of Health And Human Services	Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes
ES2329648T3 (es) *	1999-12-23	2009-11-30	The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services	Clones moleculares con genes mutados gag/pol de vih, gag de vis y env de vis.
AUPQ580300A0 (en) *	2000-02-23	2000-03-16	National Cancer Centre Of Singapore Pte Ltd	Genetic analysis
GB0009760D0 (en) *	2000-04-19	2000-06-07	Oxford Biomedica Ltd	Method
US7211659B2 (en)	2001-07-05	2007-05-01	Chiron Corporation	Polynucleotides encoding antigenic HIV type C polypeptides, polypeptides and uses thereof
US20030170614A1 (en)	2001-08-31	2003-09-11	Megede Jan Zur	Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
US6835568B2 (en)	2001-10-30	2004-12-28	Virxsys Corporation	Regulated nucleic acid expression system
ATE488595T1 (de) *	2003-05-06	2010-12-15	Nat Inst Of Advanced Ind Scien	System zur bestimmung der aktivität mehrerer gentranskriptionen
CN101365715B (zh) *	2005-10-07	2013-03-27	P·安杰莱蒂分子生物学研究所	基质金属蛋白酶11疫苗
JP6824594B2 (ja)	2014-09-11	2021-02-03	Jnc株式会社	合成遺伝子の設計方法

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WO2000039304A2 (fr) *	1998-12-31	2000-07-06	Chiron Corporation	Polynucleotides codant pour des polypeptides antigeniques du type c du vih; polypeptides et leurs utilisations
WO2000039302A2 (fr) *	1998-12-31	2000-07-06	Chiron Corporation	Expression amelioree de polypeptides hiv et production de particules de type viral

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US5434065A (en) *	1993-05-06	1995-07-18	President And Fellows Of Harvard College	In vivo selection of microbial virulence genes
US6200811B1 (en) *	1996-04-02	2001-03-13	The Regents Of The University Of California	Cell transformation vector comprising an HIV-2 packaging site nucleic acid and an HIV-1 GAG protein
US6114148C1 (en) *	1996-09-20	2012-05-01	Gen Hospital Corp	High level expression of proteins
DE69836206T2 (de) *	1997-02-07	2007-08-23	Merck & Co., Inc.	Synthetische hiv gag gene

2000
- 2000-04-26 RU RU2001131728/15A patent/RU2001131728A/ru unknown
- 2000-04-26 CA CA002369058A patent/CA2369058A1/fr not_active Abandoned
- 2000-04-26 EP EP00927069A patent/EP1183381A2/fr not_active Withdrawn
- 2000-04-26 HU HU0201019A patent/HUP0201019A2/hu unknown
- 2000-04-26 BR BR0010077-3A patent/BR0010077A/pt not_active Application Discontinuation
- 2000-04-26 JP JP2000614410A patent/JP2002542791A/ja not_active Withdrawn
- 2000-04-26 PL PL00351988A patent/PL351988A1/xx unknown
- 2000-04-26 AU AU45579/00A patent/AU778106B2/en not_active Ceased
- 2000-04-26 IL IL14609000A patent/IL146090A0/xx unknown
- 2000-04-26 WO PCT/EP2000/003765 patent/WO2000065076A2/fr not_active Ceased
2001
- 2001-10-23 NO NO20015168A patent/NO20015168L/no not_active Application Discontinuation

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Publication number	Publication date
PL351988A1 (en)	2003-07-14
AU4557900A (en)	2000-11-10
RU2001131728A (ru)	2004-02-20
BR0010077A (pt)	2002-01-15
JP2002542791A (ja)	2002-12-17
IL146090A0 (en)	2002-07-25
CA2369058A1 (fr)	2000-11-02
WO2000065076A3 (fr)	2001-12-13
EP1183381A2 (fr)	2002-03-06
HUP0201019A2 (en)	2002-08-28
NO20015168D0 (no)	2001-10-23
WO2000065076A2 (fr)	2000-11-02
NO20015168L (no)	2001-12-14

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