AU7228398A - Lck serine phosphorylation assay for t-cell activation and activation-induced cell death - Google Patents
Lck serine phosphorylation assay for t-cell activation and activation-induced cell deathInfo
- Publication number
- AU7228398A AU7228398A AU72283/98A AU7228398A AU7228398A AU 7228398 A AU7228398 A AU 7228398A AU 72283/98 A AU72283/98 A AU 72283/98A AU 7228398 A AU7228398 A AU 7228398A AU 7228398 A AU7228398 A AU 7228398A
- Authority
- AU
- Australia
- Prior art keywords
- activation
- lck
- phosphorylation assay
- serine phosphorylation
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 title 1
- 230000006044 T cell activation Effects 0.000 title 1
- 230000006786 activation induced cell death Effects 0.000 title 1
- 238000003566 phosphorylation assay Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4187897P | 1997-04-11 | 1997-04-11 | |
| US60041878 | 1997-04-11 | ||
| PCT/IB1998/000801 WO1998046996A2 (en) | 1997-04-11 | 1998-04-10 | Lck serine phosphorylation assay for t-cell activation and activation-induced cell death |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU7228398A true AU7228398A (en) | 1998-11-11 |
Family
ID=21918830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU72283/98A Abandoned AU7228398A (en) | 1997-04-11 | 1998-04-10 | Lck serine phosphorylation assay for t-cell activation and activation-induced cell death |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU7228398A (en) |
| WO (1) | WO1998046996A2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7109003B2 (en) | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
| US6682736B1 (en) | 1998-12-23 | 2004-01-27 | Abgenix, Inc. | Human monoclonal antibodies to CTLA-4 |
| AU6318300A (en) | 1999-08-05 | 2001-03-05 | Kyogo Itoh | Tumor antigen |
| US7605238B2 (en) | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| ATE354655T1 (en) | 1999-08-24 | 2007-03-15 | Medarex Inc | HUMAN ANTIBODIES TO CTLA-4 AND THEIR USES |
| AU2003234736B2 (en) | 2002-04-12 | 2008-09-25 | E. R. Squibb & Sons, L.L.C. | Methods of treatment using CTLA-4 antibodies |
| CN101325971A (en) | 2005-12-07 | 2008-12-17 | 米德列斯公司 | CTLA-4 antibody dose escalation regimens |
-
1998
- 1998-04-10 AU AU72283/98A patent/AU7228398A/en not_active Abandoned
- 1998-04-10 WO PCT/IB1998/000801 patent/WO1998046996A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998046996A2 (en) | 1998-10-22 |
| WO1998046996A3 (en) | 1999-04-01 |
| WO1998046996A9 (en) | 1999-05-06 |
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