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AU687023B2 - Use of idazoxan and derivatives thereof in preparing a drug for treating parkinson's disease and its development - Google Patents

Use of idazoxan and derivatives thereof in preparing a drug for treating parkinson's disease and its development

Info

Publication number
AU687023B2
AU687023B2 AU56530/94A AU5653094A AU687023B2 AU 687023 B2 AU687023 B2 AU 687023B2 AU 56530/94 A AU56530/94 A AU 56530/94A AU 5653094 A AU5653094 A AU 5653094A AU 687023 B2 AU687023 B2 AU 687023B2
Authority
AU
Australia
Prior art keywords
drug
disease
development
treating parkinson
idazoxan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU56530/94A
Other versions
AU5653094A (en
Inventor
Mike Briley
Francis Colpaert
Thierry Imbert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of AU5653094A publication Critical patent/AU5653094A/en
Application granted granted Critical
Publication of AU687023B2 publication Critical patent/AU687023B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

A compound of general formula (I), wherein R is a hydrogen atom, a straight or branched C1-4 alkyl radical or a straight or branched C1-4 alkoxy radical; and therapeutically acceptable salts, a racemic mixture or optically active isomers thereof; is used to prepare a drug for treating Parkinson's disease and its development.
AU56530/94A 1992-12-07 1993-12-06 Use of idazoxan and derivatives thereof in preparing a drug for treating parkinson's disease and its development Ceased AU687023B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9214694A FR2698789B1 (en) 1992-12-07 1992-12-07 Use of idazoxan and its derivatives for the preparation of a medicament intended for the treatment of Parkinson's disease and its evolution.
FR9214694 1992-12-07
PCT/FR1993/001196 WO1994013285A1 (en) 1992-12-07 1993-12-06 Use of idazoxan and derivatives thereof in preparing a drug for treating parkinson's disease and its development

Publications (2)

Publication Number Publication Date
AU5653094A AU5653094A (en) 1994-07-04
AU687023B2 true AU687023B2 (en) 1998-02-19

Family

ID=9436284

Family Applications (1)

Application Number Title Priority Date Filing Date
AU56530/94A Ceased AU687023B2 (en) 1992-12-07 1993-12-06 Use of idazoxan and derivatives thereof in preparing a drug for treating parkinson's disease and its development

Country Status (10)

Country Link
EP (1) EP0671915B1 (en)
JP (1) JPH08504203A (en)
AT (1) ATE181503T1 (en)
AU (1) AU687023B2 (en)
CA (1) CA2151039A1 (en)
DE (1) DE69325462D1 (en)
FR (1) FR2698789B1 (en)
NZ (1) NZ258591A (en)
WO (1) WO1994013285A1 (en)
ZA (1) ZA939153B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281207B1 (en) * 1999-09-15 2001-08-28 Reed Richter Treatment of movement disorders by administration of mirtazapine
FR2814368B1 (en) * 2000-09-26 2004-05-07 Pf Medicament PHARMACEUTICAL PREPARATION BASED ON OXANS
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
US7595335B2 (en) 2003-10-28 2009-09-29 Pierre Fabre Medicament Pharmaceutical composition based on idazoxan, salts, hydrates or polymorphs thereof
US8476307B2 (en) 2003-10-28 2013-07-02 Pierre Fabre Medicament Pharmaceutical composition based on idazoxan, salts, hydrates or polymorphs thereof
FR2861299B1 (en) 2003-10-28 2006-01-27 Pf Medicament PHARMACEUTICAL COMPOSITIONS BASED ON IDASOXAN DERIVATIVES IN POLYMORPHIC FORMS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16249A (en) * 1980-02-04 1983-08-16 Reckitt & Colmann Prod Ltd Imidazoline derivatives,its pharmaceutical composition and method of use
NZ199469A (en) * 1981-01-30 1984-03-16 Reckitt & Colmann Prod Ltd Benzodioxanyl-2-imidazoline derivatives and pharmaceutical compositions
NZ203680A (en) * 1982-04-17 1985-08-16 Reckitt & Colmann Prod Ltd Imidazolines and pharmaceutical compositions
FR2669030B1 (en) * 1990-11-14 1992-12-31 Adir NEW IMIDAZOLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
FR2698789A1 (en) 1994-06-10
ATE181503T1 (en) 1999-07-15
CA2151039A1 (en) 1994-06-23
FR2698789B1 (en) 1995-03-03
WO1994013285A1 (en) 1994-06-23
JPH08504203A (en) 1996-05-07
ZA939153B (en) 1994-08-05
NZ258591A (en) 1997-06-24
AU5653094A (en) 1994-07-04
EP0671915A1 (en) 1995-09-20
DE69325462D1 (en) 1999-07-29
EP0671915B1 (en) 1999-06-23

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired