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AU6663990A - Chimeric mouse-human antibodies with specificity to hiv antigens - Google Patents

Chimeric mouse-human antibodies with specificity to hiv antigens

Info

Publication number
AU6663990A
AU6663990A AU66639/90A AU6663990A AU6663990A AU 6663990 A AU6663990 A AU 6663990A AU 66639/90 A AU66639/90 A AU 66639/90A AU 6663990 A AU6663990 A AU 6663990A AU 6663990 A AU6663990 A AU 6663990A
Authority
AU
Australia
Prior art keywords
specificity
human antibodies
chimeric mouse
hiv antigens
hiv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU66639/90A
Inventor
Marc D. Better
Pradip Ghosh-Dastidar
Arnold H. Horwitz
Randy R. Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Xoma Royalty Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Xoma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea, Xoma Corp filed Critical Green Cross Corp Japan
Publication of AU6663990A publication Critical patent/AU6663990A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C07K16/1145
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • C07K16/1143
    • C07K16/1147
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU66639/90A 1989-11-13 1990-11-13 Chimeric mouse-human antibodies with specificity to hiv antigens Abandoned AU6663990A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43370389A 1989-11-13 1989-11-13
US433703 1989-11-13

Publications (1)

Publication Number Publication Date
AU6663990A true AU6663990A (en) 1991-05-16

Family

ID=23721227

Family Applications (2)

Application Number Title Priority Date Filing Date
AU66639/90A Abandoned AU6663990A (en) 1989-11-13 1990-11-13 Chimeric mouse-human antibodies with specificity to hiv antigens
AU69530/91A Abandoned AU6953091A (en) 1989-11-13 1990-11-13 Chimeric mouse human antibodies with specificity to hiv antigens

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU69530/91A Abandoned AU6953091A (en) 1989-11-13 1990-11-13 Chimeric mouse human antibodies with specificity to hiv antigens

Country Status (6)

Country Link
EP (1) EP0453561A4 (en)
JP (2) JPH03206888A (en)
KR (2) KR910009285A (en)
AU (2) AU6663990A (en)
CA (2) CA2044609A1 (en)
WO (1) WO1991007494A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0519866A1 (en) * 1991-06-18 1992-12-23 Ciba-Geigy Ag Novel anti-HIV antibodies
WO1994004574A1 (en) * 1991-08-22 1994-03-03 Nissin Shokuhin Kabushiki Kaisha Hiv immunotherapeutics
EP0581353A1 (en) * 1992-07-03 1994-02-02 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Monoclonal antibodies to HiV-1 gp120, cell lines producing them and corresponding epitope structures
WO1998001476A1 (en) * 1996-07-10 1998-01-15 Nabi Highly synergistic neutralization of hiv through combinations of monoclonal and polyclonal antibodies
AU6518698A (en) * 1997-03-28 1998-10-22 Seikagaku Corporation Novel anti-hiv complexes and medicinal compositions
US20030035798A1 (en) 2000-08-16 2003-02-20 Fang Fang Humanized antibodies
JP2005522192A (en) 2001-07-19 2005-07-28 パーラン セラピューティクス, インコーポレイテッド Multimeric proteins and methods of making and using multimeric proteins
EP1960435A1 (en) * 2005-12-15 2008-08-27 Micromet AG Domain-grafted antibodies
US9944693B2 (en) * 2013-12-08 2018-04-17 Peptcell Limited HIV antigens and antibodies and compositions, uses and methods thereof
CN116143909B (en) * 2021-11-20 2023-10-31 东莞市朋志生物科技有限公司 anti-HIV-1P 24 antibody and preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904581A (en) * 1986-05-06 1990-02-27 Epitope, Inc. Method of detecting AIDS virus infection
JP2520464B2 (en) * 1987-05-29 1996-07-31 タノツクス・バイオシステムズ・インコーポレーテツド Monoclonal antibody that neutralizes HIV-1
WO1989005820A1 (en) * 1987-12-21 1989-06-29 Arch Development Corporation Hiv-related antigens and antibodies
JP2646007B2 (en) * 1988-01-30 1997-08-25 財団法人 化学及血清療法研究所 Gene fragment encoding anti-HIV antibody variable region, anti-HIV chimeric antibody expressed using the same, and method for producing the same

Also Published As

Publication number Publication date
EP0453561A4 (en) 1993-02-10
CA2044609A1 (en) 1991-05-14
KR910009285A (en) 1991-06-28
JPH04503609A (en) 1992-07-02
AU6953091A (en) 1991-06-13
KR920701441A (en) 1992-08-11
CA2044627A1 (en) 1991-05-14
JPH03206888A (en) 1991-09-10
WO1991007494A1 (en) 1991-05-30
EP0453561A1 (en) 1991-10-30

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