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AU630901B2 - Cyclosporine binding protein and use in an assay for biologically-active cyclosporine - Google Patents

Cyclosporine binding protein and use in an assay for biologically-active cyclosporine

Info

Publication number
AU630901B2
AU630901B2 AU45607/89A AU4560789A AU630901B2 AU 630901 B2 AU630901 B2 AU 630901B2 AU 45607/89 A AU45607/89 A AU 45607/89A AU 4560789 A AU4560789 A AU 4560789A AU 630901 B2 AU630901 B2 AU 630901B2
Authority
AU
Australia
Prior art keywords
cyclosporine
biologically
assay
binding protein
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU45607/89A
Other versions
AU4560789A (en
Inventor
Steven J Soldin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Research Institute
Original Assignee
Childrens Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Research Institute filed Critical Childrens Research Institute
Publication of AU4560789A publication Critical patent/AU4560789A/en
Assigned to CHILDREN'S RESEARCH INSTITUTE reassignment CHILDREN'S RESEARCH INSTITUTE Alteration of Name(s) of Applicant(s) under S113 Assignors: Children's National Medical Center, Inc
Application granted granted Critical
Publication of AU630901B2 publication Critical patent/AU630901B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493—Immunosupressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU45607/89A 1988-12-02 1989-11-27 Cyclosporine binding protein and use in an assay for biologically-active cyclosporine Ceased AU630901B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27917688A 1988-12-02 1988-12-02
US279176 1988-12-02

Publications (2)

Publication Number Publication Date
AU4560789A AU4560789A (en) 1990-06-07
AU630901B2 true AU630901B2 (en) 1992-11-12

Family

ID=23067955

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45607/89A Ceased AU630901B2 (en) 1988-12-02 1989-11-27 Cyclosporine binding protein and use in an assay for biologically-active cyclosporine

Country Status (5)

Country Link
EP (1) EP0372862A3 (en)
JP (1) JPH02209897A (en)
KR (1) KR900009069A (en)
AU (1) AU630901B2 (en)
CA (1) CA2004387C (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2048302A1 (en) * 1990-08-15 1992-02-16 Victoria P. Meucci Solubilization reagent for biological test samples
US5763590A (en) * 1991-10-11 1998-06-09 Vertex Pharmaceuticals, Inc. Isolation of an Mr 52,000 FK506 binding protein and molecular cloning of a corresponding human cDNA
US20030220234A1 (en) 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
ES2266564T3 (en) 2001-10-19 2007-03-01 Isotechnika Inc. SYNTHESIS OF CYCLOPORINE ANALOGS.
US7642059B2 (en) * 2005-09-07 2010-01-05 Roche Diagnostics Operations, Inc. Single receptor assays for immunosuppressive drugs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285603A2 (en) * 1987-04-03 1988-10-05 Biomedica Handelsgesellschaft M.B.H. Method for the determination of cyclosporin A in blood

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285603A2 (en) * 1987-04-03 1988-10-05 Biomedica Handelsgesellschaft M.B.H. Method for the determination of cyclosporin A in blood

Also Published As

Publication number Publication date
CA2004387A1 (en) 1990-06-02
CA2004387C (en) 2000-05-09
AU4560789A (en) 1990-06-07
EP0372862A2 (en) 1990-06-13
JPH02209897A (en) 1990-08-21
KR900009069A (en) 1990-07-02
EP0372862A3 (en) 1990-12-27

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