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AU6228000A - The use of retinoid receptor antagonists in the treatment of prostate carcinoma - Google Patents

The use of retinoid receptor antagonists in the treatment of prostate carcinoma

Info

Publication number
AU6228000A
AU6228000A AU62280/00A AU6228000A AU6228000A AU 6228000 A AU6228000 A AU 6228000A AU 62280/00 A AU62280/00 A AU 62280/00A AU 6228000 A AU6228000 A AU 6228000A AU 6228000 A AU6228000 A AU 6228000A
Authority
AU
Australia
Prior art keywords
treatment
receptor antagonists
prostate carcinoma
retinoid receptor
retinoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU62280/00A
Inventor
Geoffrey Brown
Roshantha A. Chandraratna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Sales LLC
Original Assignee
Allergan Sales LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Sales LLC filed Critical Allergan Sales LLC
Publication of AU6228000A publication Critical patent/AU6228000A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU62280/00A 1999-07-23 2000-07-21 The use of retinoid receptor antagonists in the treatment of prostate carcinoma Abandoned AU6228000A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14528799P 1999-07-23 1999-07-23
US60145287 1999-07-23
PCT/US2000/019849 WO2001007028A2 (en) 1999-07-23 2000-07-21 The use of retinoid receptor antagonists in the treatment of prostate carcinoma

Publications (1)

Publication Number Publication Date
AU6228000A true AU6228000A (en) 2001-02-13

Family

ID=22512422

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62280/00A Abandoned AU6228000A (en) 1999-07-23 2000-07-21 The use of retinoid receptor antagonists in the treatment of prostate carcinoma

Country Status (2)

Country Link
AU (1) AU6228000A (en)
WO (1) WO2001007028A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007513880A (en) 2003-11-25 2007-05-31 ノボ　ノルディスク　アクティーゼルスカブ New salicylanilide
EP1937244B1 (en) 2005-09-30 2018-07-25 Io Therapeutics, LLC Treatment of cancer with specific rxr agonists
US10653650B2 (en) 2011-12-13 2020-05-19 Io Therapeutics, Inc. Treatment of diseases by concurrently eliciting remyelination effects and immunomodulatory effects using selective RXR agonists
AU2012352149B2 (en) 2011-12-13 2017-06-01 Io Therapeutics, Inc. Autoimmune disorder treatment using RXR agonists
CN108289958A (en) 2015-10-31 2018-07-17 Io治疗公司 Combinations of RXR agonists and thyroid hormones in the treatment of neurological disorders
ES2898676T3 (en) 2015-11-25 2022-03-08 Io Therapeutics Inc Selective CYP26-resistant rar-alpha agonists in cancer treatment
CN109310769B (en) 2016-03-10 2022-07-05 Io治疗公司 Treatment of autoimmune diseases with RXR agonists in combination with thyroid hormones
KR20180121983A (en) 2016-03-10 2018-11-09 아이오 테라퓨틱스, 인크. Treatment of muscle disorders using a combination of RXR agonists and thyroid hormones
EP3468600A4 (en) 2016-06-10 2019-11-13 IO Therapeutics, Inc. RETINOID COMPOUNDS AND RELECTIVE REXINOIDS OF THE RECEPTOR AND IMMUNE MODULATORS FOR IMMUNOTHERAPY OF CANCER
BR112020000553A2 (en) 2017-07-11 2020-07-21 Vertex Pharmaceuticals Incorporated carboxamides as sodium channel modulators
KR20200029543A (en) 2017-07-13 2020-03-18 아이오 테라퓨틱스, 인크. Receptor subtypes and functional selective retinoids and rexinoid compounds combined with immunomodulators for cancer immunotherapy
CN111148514A (en) 2017-08-31 2020-05-12 Io治疗公司 RAR selective agonists for cancer immunotherapy in combination with immunomodulators
WO2019060600A1 (en) 2017-09-20 2019-03-28 Io Therapeutics, Inc. Treatment of disease with esters of selective rxr agonists
WO2020146612A1 (en) 2019-01-10 2020-07-16 Vertex Pharmaceuticals Incorporated Esters and carbamates as modulators of sodium channels
US12441703B2 (en) 2019-01-10 2025-10-14 Vertex Pharmaceuticals Incorporated Carboxamides as modulators of sodium channels
US10966950B2 (en) 2019-06-11 2021-04-06 Io Therapeutics, Inc. Use of an RXR agonist in treating HER2+ cancers
MX2024006978A (en) 2021-12-07 2024-07-19 Io Therapeutics Inc Use of an rxr agonist and taxanes in treating her2+ cancers.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958954A (en) * 1995-09-01 1999-09-28 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US5688957A (en) * 1995-12-29 1997-11-18 Allergan (3"-thioxacyclohex-1"-enyl)!-but-3'-ene-1'-ynyl!aryl and (3"-thioxacyclohex-1"-enyl)!-but-3'-ene-1'-ynyl!heteroaryl carboxylic acids and esters having retinoid-like biological activity
US5763635A (en) * 1996-06-21 1998-06-09 Allergan Tetrahydronaphthalene derivatives substituted in the 8 position with alkyhidene groups having retinoid and/or retinoid antagonist-like biological activity
US5808124A (en) * 1996-06-21 1998-09-15 Allergan O- or S-substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US5773594A (en) * 1996-06-21 1998-06-30 Allergan Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US5739338A (en) * 1996-11-05 1998-04-14 Allergan N-aryl substituted tetrahydroquinolines having retinoid agonist, retinoid antagonist or retinoid inverse agonist type biological activity
US5728846A (en) * 1996-12-12 1998-03-17 Allergan Benzo 1,2-g!-chrom-3-ene and benzo 1,2-g!-thiochrom-3-ene derivatives
US5919970A (en) * 1997-04-24 1999-07-06 Allergan Sales, Inc. Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity

Also Published As

Publication number Publication date
WO2001007028A2 (en) 2001-02-01
WO2001007028A3 (en) 2001-08-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase