[go: up one dir, main page]

AU6180096A - Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps - Google Patents

Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps

Info

Publication number
AU6180096A
AU6180096A AU61800/96A AU6180096A AU6180096A AU 6180096 A AU6180096 A AU 6180096A AU 61800/96 A AU61800/96 A AU 61800/96A AU 6180096 A AU6180096 A AU 6180096A AU 6180096 A AU6180096 A AU 6180096A
Authority
AU
Australia
Prior art keywords
indanol
bioconversion
dioxygenase
indene
stereoisomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61800/96A
Other languages
English (en)
Inventor
Barry C. Buckland
Michel M Chartrain
Neal C. Connors
Francis P. Gailliot
Randolph L. Greasham
Chanyong Lee
Roger C. Olewinski Jr.
Paul J. Reider
F. Edward Roberts
Chris H Senanayake
Thomas R. Verhoeven
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9602938.4A external-priority patent/GB9602938D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU6180096A publication Critical patent/AU6180096A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/38Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU61800/96A 1995-06-20 1996-06-14 Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps Abandoned AU6180096A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36095P 1995-06-20 1995-06-20
US000360 1995-06-20
GBGB9602938.4A GB9602938D0 (en) 1996-02-13 1996-02-13 Conversion of indene
GB9602938 1996-02-13
PCT/US1996/010445 WO1997000966A1 (en) 1995-06-20 1996-06-14 Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps

Publications (1)

Publication Number Publication Date
AU6180096A true AU6180096A (en) 1997-01-22

Family

ID=26308684

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61800/96A Abandoned AU6180096A (en) 1995-06-20 1996-06-14 Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps

Country Status (5)

Country Link
CN (1) CN1194006A (pt)
AR (1) AR002536A1 (pt)
AU (1) AU6180096A (pt)
BR (1) BR9608804A (pt)
WO (1) WO1997000966A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420067D0 (en) * 1994-10-05 1994-11-16 Zeneca Ltd Process
US5824540A (en) * 1995-06-20 1998-10-20 Merck & Co., Inc. Pseudomonas putida strain with dioxygenase activity
US5858737A (en) * 1995-06-20 1999-01-12 Merck & Co., Inc. Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps
WO1997025436A1 (en) * 1996-01-12 1997-07-17 Nippon Steel Chemical Co., Ltd. Processes for producing indane derivatives
NL1005832C2 (nl) * 1997-04-17 1998-10-20 Dsm Nv Werkwijze voor de bereiding van CIS-(1S,2R)-aminoindanol.
GB2336841A (en) 1998-04-28 1999-11-03 Merck & Co Inc Preparation of cis-(is,2r)-indanediol by the microbial reduction of 1,2-indanedione
AU5516299A (en) * 1998-08-13 2000-03-06 Lonza A.G. Method for producing indane derivatives
NL1010354C2 (nl) * 1998-10-20 2000-04-25 Dsm Biotech Gmbh Bereiding van aminoalcoholen.
PT2280721T (pt) * 2008-04-17 2018-02-16 Io Biotech Aps Imunoterapia à base de indoleamina 2,3-dioxigenase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599985A (en) * 1993-09-14 1997-02-04 Sepracor, Inc. Optically pure 1-amido-2-indanols
US5420353A (en) * 1994-03-11 1995-05-30 Merck & Co., Inc. Regiospecific process to make cis-1-amino-2-alkanol from epoxide
GB9420067D0 (en) * 1994-10-05 1994-11-16 Zeneca Ltd Process

Also Published As

Publication number Publication date
WO1997000966A1 (en) 1997-01-09
AR002536A1 (es) 1998-03-25
CN1194006A (zh) 1998-09-23
BR9608804A (pt) 1999-02-17

Similar Documents

Publication Publication Date Title
AU8122198A (en) Process for the preparation of methanol and hydrogen
AU5730199A (en) Catalyst and process for the oxidation of methane to methanol
AU3515797A (en) Catalytic reactor for marine application
AU3732495A (en) Hydrocarbon conversion
AU3018195A (en) Hydrocarbon conversion catalysts
AU7711298A (en) Hydrocarbon conversion process
EP0690621A3 (en) Sample rate converter and sample rate conversion method
AU4723296A (en) Compositions having depigmenting activity, and uses thereof
AU7576898A (en) Composition useful for hydrocarbon conversion process and preparation thereof
MY133693A (en) Conversion of methanol to gasoline
AU6180096A (en) Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps
AU4149697A (en) Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps
AU2785995A (en) Offshore wind-/wave-energy converter
AU4858397A (en) Tidal energy converter
AU1910897A (en) Process for preparing catalytically active coatings for the synthesis of hydrogen cyanide
AU3977697A (en) Conversion of indene to (1s)-amino-(2r)-indanol free of any stereoisomer, by combination of monooxygenase bioconversion and chemical steps
AU4071197A (en) Phenotypic conversion of drug-resistant bacteria to drug-sensitivity
AU5749796A (en) Quantitative conversion of indene to (1s,2r) indene oxide an d (1s,2r)-indandiol by combination of haloperoxidase bioconv ersion and chemical steps
AU4994996A (en) Composition for the treatment of diarrhea, its use and its preparation
CA2316933A1 (en) A composition for converting hydrocarbons comprising a siliconized acid-treated zeolite containing zinc and boron and method of making such catalyst
AU7710598A (en) High stability zeolite catalyst composition and hydrocarbon conversion process
AU5226798A (en) Use of paracetamol as depigmenting agent
AU6761394A (en) New method and supported catalysts for converting c1-c4 hydrocarbons to c2-olefinic hydrocarbons
GB9620737D0 (en) Conversion of indene to(IS)-amino-(2R)-indanol free of any stereoisomer,by combination of monooxygenase bioconversion and chemical steps
AU1990695A (en) Natural gas conversion to higher hydrocarbons