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AU5951798A - Oral application of (+)-O-demethyltramadol as a pain- killing drug - Google Patents

Oral application of (+)-O-demethyltramadol as a pain- killing drug

Info

Publication number
AU5951798A
AU5951798A AU59517/98A AU5951798A AU5951798A AU 5951798 A AU5951798 A AU 5951798A AU 59517/98 A AU59517/98 A AU 59517/98A AU 5951798 A AU5951798 A AU 5951798A AU 5951798 A AU5951798 A AU 5951798A
Authority
AU
Australia
Prior art keywords
demethyltramadol
pain
oral application
killing drug
killing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU59517/98A
Inventor
Elmar Josef Friderichs
Werner Winter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Chemie Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH, Chemie Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU5951798A publication Critical patent/AU5951798A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU59517/98A 1997-03-25 1998-03-25 Oral application of (+)-O-demethyltramadol as a pain- killing drug Abandoned AU5951798A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19712398 1997-03-25
DE19712398A DE19712398A1 (en) 1997-03-25 1997-03-25 Oral use of (+) - 0-demethyltramadol as a pain reliever

Publications (1)

Publication Number Publication Date
AU5951798A true AU5951798A (en) 1998-10-01

Family

ID=7824498

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59517/98A Abandoned AU5951798A (en) 1997-03-25 1998-03-25 Oral application of (+)-O-demethyltramadol as a pain- killing drug

Country Status (14)

Country Link
EP (1) EP0870499A1 (en)
JP (1) JPH1112166A (en)
KR (1) KR19980080580A (en)
CN (1) CN1196932A (en)
AU (1) AU5951798A (en)
BR (1) BR9801839A (en)
CA (1) CA2232930A1 (en)
DE (1) DE19712398A1 (en)
HU (1) HUP9800623A3 (en)
IL (1) IL123788A0 (en)
NO (1) NO981320L (en)
PE (1) PE62399A1 (en)
PL (1) PL325509A1 (en)
UY (1) UY24934A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010623A1 (en) * 1999-10-05 2001-07-07 Gruenenthal Chemie USE OF (+) - TRAMADOL AND / OR O-DEMETILTRAMADOL FOR TREATMENT OF INCREASED URINARY URGENCY AND / OR URINARY INCONTINENCE
DE10108123A1 (en) * 2001-02-21 2002-10-02 Gruenenthal Gmbh drug combination
US20110251286A1 (en) 2010-03-10 2011-10-13 Gruenenthal Gmbh Crystalline salts and/or co-crystals of O-desmethyltramadol
US10702485B2 (en) 2011-07-09 2020-07-07 Syntrix Biosystems Inc. Compositions and methods for overcoming resistance to tramadol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU657351B2 (en) * 1991-09-06 1995-03-09 Mcneilab, Inc. Compositions comprising a tramadol material and any of codeine, oxycodone or hydrocodone and their use
AU661723B2 (en) * 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
DE4315525B4 (en) * 1993-05-10 2010-04-15 Euro-Celtique S.A. Pharmaceutical composition
DE4329794C2 (en) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadol salt-containing drugs with delayed release
DE19525137C2 (en) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexane compounds as intermediates for the preparation of pharmaceutical agents
DE19601744C2 (en) * 1996-01-19 1998-04-16 Gruenenthal Gmbh Process for the preparation of the enantiomers of O-demethyltramadol

Also Published As

Publication number Publication date
CA2232930A1 (en) 1998-09-25
DE19712398A1 (en) 1998-10-01
HU9800623D0 (en) 1998-05-28
BR9801839A (en) 2000-01-18
KR19980080580A (en) 1998-11-25
IL123788A0 (en) 1998-10-30
UY24934A1 (en) 1998-04-21
CN1196932A (en) 1998-10-28
PL325509A1 (en) 1998-09-28
NO981320L (en) 1998-09-28
NO981320D0 (en) 1998-03-24
JPH1112166A (en) 1999-01-19
HUP9800623A3 (en) 1999-03-29
EP0870499A1 (en) 1998-10-14
HUP9800623A2 (en) 1999-01-28
PE62399A1 (en) 1999-07-10

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period