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AU581101B2 - Anti-tumour platinum complexes, their preparation and their use - Google Patents

Anti-tumour platinum complexes, their preparation and their use

Info

Publication number
AU581101B2
AU581101B2 AU62415/86A AU6241586A AU581101B2 AU 581101 B2 AU581101 B2 AU 581101B2 AU 62415/86 A AU62415/86 A AU 62415/86A AU 6241586 A AU6241586 A AU 6241586A AU 581101 B2 AU581101 B2 AU 581101B2
Authority
AU
Australia
Prior art keywords
preparation
platinum complexes
tumour
tumour platinum
platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU62415/86A
Other versions
AU6241586A (en
Inventor
Toshihiko Hashimoto
Yukiko Kameyama
Koichi Kitamura
Fusaaki Shimizu
Yukio Sugimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of AU6241586A publication Critical patent/AU6241586A/en
Application granted granted Critical
Publication of AU581101B2 publication Critical patent/AU581101B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Platinum complexes of formula (I): <CHEM> (wherein L<1> and L<2> are ligands, X<p-> is an anion and n is 0, 1, 2 or 3) have anti-tumour activity and may be prepared by condensing a 1,2-diaminocyclohexane-platinum (II) complex with a cyclic alkylene urea.
AU62415/86A 1985-09-06 1986-09-05 Anti-tumour platinum complexes, their preparation and their use Ceased AU581101B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP60-197097 1985-09-06
JP19709785 1985-09-06

Publications (2)

Publication Number Publication Date
AU6241586A AU6241586A (en) 1987-03-12
AU581101B2 true AU581101B2 (en) 1989-02-09

Family

ID=16368672

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62415/86A Ceased AU581101B2 (en) 1985-09-06 1986-09-05 Anti-tumour platinum complexes, their preparation and their use

Country Status (15)

Country Link
EP (1) EP0214862B1 (en)
JP (1) JPH0655752B2 (en)
KR (1) KR890004351B1 (en)
CN (1) CN1016345B (en)
AT (1) ATE61560T1 (en)
AU (1) AU581101B2 (en)
CA (1) CA1281327C (en)
DE (1) DE3678070D1 (en)
DK (1) DK166825B1 (en)
ES (1) ES2001669A6 (en)
FI (1) FI83086C (en)
HU (1) HU196606B (en)
NO (1) NO172184C (en)
PH (1) PH25038A (en)
SU (1) SU1565347A3 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665648B2 (en) * 1985-09-25 1994-08-24 塩野義製薬株式会社 Stable freeze-drying formulation of platinum anticancer substance
HU199492B (en) * 1987-05-08 1990-02-28 Sankyo Co Process for producing antitumour platinum complexes and pharmaceutical compositions comprising same
DE69713763T2 (en) * 1996-03-11 2003-03-13 Yoshinori Kidani BINUCLEAR PLATINUM COMPLEXES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THIS COMPLEX
ITMI991508A1 (en) * 1999-07-09 2001-01-09 Novuspharma Spa COMPLEX BIS-PLATINUM NITRATES WITH POLYAMINIC LIGANDS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207416A (en) * 1974-09-05 1980-06-10 Engelhard Minerals & Chemicals Corporation Ethylenediamineplatinum(II) 2,4-dioxopyrimidine complexes
US4419351A (en) * 1977-06-03 1983-12-06 Research Corporation Platinum-dioxopyrimidine complexes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH617587A5 (en) * 1974-09-05 1980-06-13 Engelhard Min & Chem

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207416A (en) * 1974-09-05 1980-06-10 Engelhard Minerals & Chemicals Corporation Ethylenediamineplatinum(II) 2,4-dioxopyrimidine complexes
US4419351A (en) * 1977-06-03 1983-12-06 Research Corporation Platinum-dioxopyrimidine complexes

Also Published As

Publication number Publication date
KR870003129A (en) 1987-04-15
ES2001669A6 (en) 1988-06-01
EP0214862B1 (en) 1991-03-13
CA1281327C (en) 1991-03-12
FI863599L (en) 1987-03-07
DK166825B1 (en) 1993-07-19
HUT41808A (en) 1987-05-28
DK426486A (en) 1987-03-07
DE3678070D1 (en) 1991-04-18
NO172184C (en) 1993-06-16
NO172184B (en) 1993-03-08
HU196606B (en) 1988-12-28
FI863599A0 (en) 1986-09-05
NO863553D0 (en) 1986-09-05
AU6241586A (en) 1987-03-12
CN1016345B (en) 1992-04-22
SU1565347A3 (en) 1990-05-15
FI83086C (en) 1991-05-27
NO863553L (en) 1987-03-09
JPS62149692A (en) 1987-07-03
ATE61560T1 (en) 1991-03-15
KR890004351B1 (en) 1989-10-31
PH25038A (en) 1991-01-28
EP0214862A2 (en) 1987-03-18
FI83086B (en) 1991-02-15
DK426486D0 (en) 1986-09-05
EP0214862A3 (en) 1987-12-09
CN86106751A (en) 1987-03-25
JPH0655752B2 (en) 1994-07-27

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