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AU5802894A - New substituted azetidinones as anti-inflammatory and antidegenerative agents - Google Patents

New substituted azetidinones as anti-inflammatory and antidegenerative agents

Info

Publication number
AU5802894A
AU5802894A AU58028/94A AU5802894A AU5802894A AU 5802894 A AU5802894 A AU 5802894A AU 58028/94 A AU58028/94 A AU 58028/94A AU 5802894 A AU5802894 A AU 5802894A AU 5802894 A AU5802894 A AU 5802894A
Authority
AU
Australia
Prior art keywords
inflammatory
new substituted
substituted azetidinones
antidegenerative agents
antidegenerative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU58028/94A
Inventor
Philip Davies
James B. Doherty
Paul E. Finke
William K. Hagmann
John L. Humes
Amy L. Kissinger
Edward A Luedke
Malcolm Maccoss
Richard A. Mumford
Shrenik K. Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/992,414 external-priority patent/US5348953A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU5802894A publication Critical patent/AU5802894A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU58028/94A 1992-12-17 1993-12-15 New substituted azetidinones as anti-inflammatory and antidegenerative agents Abandoned AU5802894A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/992,414 US5348953A (en) 1991-06-25 1992-12-17 Substituted azetidinones as anti-inflammatory and antidegenerative agents
PCT/US1993/012229 WO1994013636A1 (en) 1992-12-17 1993-12-15 New substituted azetidinones as anti-inflammatory and antidegenerative agents
US992414 2001-11-16

Publications (1)

Publication Number Publication Date
AU5802894A true AU5802894A (en) 1994-07-04

Family

ID=25538317

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58028/94A Abandoned AU5802894A (en) 1992-12-17 1993-12-15 New substituted azetidinones as anti-inflammatory and antidegenerative agents

Country Status (2)

Country Link
AU (1) AU5802894A (en)
WO (1) WO1994013636A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0869943A1 (en) * 1995-12-08 1998-10-14 Smithkline Beecham Plc Monocyclic beta-lactame derivatives for treatment of atherosclerosis
WO1997041098A1 (en) * 1996-04-26 1997-11-06 Smithkline Beecham Plc Azetidinone derivatives for the treatment of atherosclerosis
US8604055B2 (en) 2004-12-31 2013-12-10 Dr. Reddy's Laboratories Ltd. Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
KR101238525B1 (en) 2004-12-31 2013-02-28 레디 유에스 테라퓨틱스 인코포레이티드 Novel benzylamine derivatives as cetp inhibitors
EP2590951B1 (en) 2010-07-09 2015-01-07 Pfizer Limited Benzenesulfonamides useful as sodium channel inhibitors
CA2801032A1 (en) 2010-07-12 2012-01-19 Pfizer Limited N-sulfonylbenzamide derivatives useful as voltage gated sodium channel inhibitors
WO2012007869A2 (en) 2010-07-12 2012-01-19 Pfizer Limited Chemical compounds
JP2013532186A (en) 2010-07-12 2013-08-15 ファイザー・リミテッド Compound
EP2593428B1 (en) 2010-07-12 2014-11-19 Pfizer Limited N-sulfonylbenzamides as inhibitors of voltage-gated sodium channels
ES2532357T3 (en) 2010-07-12 2015-03-26 Pfizer Limited Sulfonamide derivatives as Nav1.7 inhibitors for pain treatment
CN116942661B (en) * 2023-08-01 2024-10-15 深圳市中医院 Application of L635 in construction of mouse spasmolytic polypeptide expression metaplasia model

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680391A (en) * 1983-12-01 1987-07-14 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
IL89835A0 (en) * 1988-04-11 1989-12-15 Merck & Co Inc Substituted azetidinones,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO1994013636A1 (en) 1994-06-23

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