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AU5858690A - Polymer/antibiotic conjugate - Google Patents

Polymer/antibiotic conjugate

Info

Publication number
AU5858690A
AU5858690A AU58586/90A AU5858690A AU5858690A AU 5858690 A AU5858690 A AU 5858690A AU 58586/90 A AU58586/90 A AU 58586/90A AU 5858690 A AU5858690 A AU 5858690A AU 5858690 A AU5858690 A AU 5858690A
Authority
AU
Australia
Prior art keywords
polymer
antibiotic conjugate
antibiotic
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU58586/90A
Inventor
Lois Aldwin
Stacey Gauney
Eric S. Groves
Danute E. Nitecki
Alfred A. Rudolph
Jeffrey L. Winkelhake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of AU5858690A publication Critical patent/AU5858690A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU58586/90A 1989-06-14 1990-06-08 Polymer/antibiotic conjugate Abandoned AU5858690A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36591489A 1989-06-14 1989-06-14
US365914 1989-06-14

Publications (1)

Publication Number Publication Date
AU5858690A true AU5858690A (en) 1991-01-08

Family

ID=23440913

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58586/90A Abandoned AU5858690A (en) 1989-06-14 1990-06-08 Polymer/antibiotic conjugate

Country Status (3)

Country Link
AU (1) AU5858690A (en)
CA (1) CA2018833A1 (en)
WO (1) WO1990015628A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622685A (en) * 1990-05-30 1997-04-22 Deutches Krebsforchunszentrum Stiftung Des Offentlichen Rechts Polyether-substituted porphyrin anti-tumor agents
ES2068587T3 (en) 1990-05-30 1995-04-16 Deutsches Krebsforsch TUMOR MEDICINES REPLACED WITH POLYETER.
US6326353B1 (en) * 1993-03-23 2001-12-04 Sequus Pharmaceuticals, Inc. Enhanced circulation effector composition and method
US5446090A (en) 1993-11-12 1995-08-29 Shearwater Polymers, Inc. Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
US5629384A (en) * 1994-05-17 1997-05-13 Consiglio Nazionale Delle Ricerche Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces
US5567685A (en) * 1994-08-16 1996-10-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Water-Soluble polyene conjugate
DE19514087A1 (en) * 1995-04-13 1996-10-17 Deutsches Krebsforsch Conjugate of an active ingredient, a polyether and possibly a native protein that is not considered foreign to the body
CA2177644A1 (en) * 1995-05-31 1996-12-01 Peter D. Senter Polymeric prodrugs for beta-lactamase and uses thereof
US6011008A (en) * 1997-01-08 2000-01-04 Yissum Research Developement Company Of The Hebrew University Of Jerusalem Conjugates of biologically active substances
US6380356B1 (en) 1999-12-07 2002-04-30 Advanced Medicine, Inc. Multivalent polymyxin antibiotics
GR1003871B (en) * 2000-05-25 2002-04-19 Γεωργιος Σαμωνης Anti-mucelia pharmaceutical materials with a controlled yield; new, water soluble polymer derivatives of sorbic acid, nystatine and amphotericine b
AU2001266201A1 (en) * 2000-07-01 2002-01-14 M.L. Laboratories Plc Medicaments
ITMI20011238A1 (en) * 2001-06-12 2002-12-12 Bartholdy Consultadoria E Serv POLYSACCHARIDIC POLYMERS OF NATURAL ORIGIN CHEMICALLY CONJUGATED AS PHARMACOLOGICALLY OR BIOLOGICALLY ACTIVE SUBSTANCES AND THEIR PROPERTIES
DE10209821A1 (en) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Coupling of proteins to a modified polysaccharide
US7452533B2 (en) 2002-03-26 2008-11-18 Biosynexus Incorporated Antimicrobial polymer conjugate containing lysostaphin and polyethylene glycol
AU2003273413A1 (en) * 2002-10-08 2004-05-04 Fresenius Kabi Deutschland Gmbh Pharmaceutically active oligosaccharide conjugates
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
WO2007025178A2 (en) * 2005-08-26 2007-03-01 New York University Rolyvalent multimeric compositions containing active polypeptides, pharmaceutical compositions and methods of using the same
CN100475270C (en) * 2006-01-20 2009-04-08 清华大学 Medicine for treating tumor and application thereof
CN101002945B (en) * 2006-01-20 2012-09-05 清华大学 Novel complex used for treating tumor
US7919480B2 (en) 2007-05-03 2011-04-05 Ethicon, Inc. Polymers having covalently bound antibiotic agents
IT1395129B1 (en) 2009-07-30 2012-09-05 Franzoni Filati S P A AMINOGLICOSIDES AND PREGELATINIZED AMINOGLYCOSIDES COVALENTLY COMBINED WITH COTTON
EP2723452A2 (en) * 2011-06-22 2014-04-30 Vyome Biosciences Pvt Ltd Conjugate-based antifungal and antibacterial prodrugs
BR112014025737A2 (en) 2012-04-16 2017-07-04 Cantab Biopharmaceuticals Patents Ltd method for administering a therapeutic agent, method for preventing entry of a therapeutic agent, method for modulating the rate of release of a therapeutic agent, therapeutic agent, dosage forms, method of treating a disease and parts kit
CN104055787B (en) * 2013-07-25 2017-04-26 北京蓝贝望生物医药科技股份有限公司 Medicinal water-soluble antifungal macromolecular compound
US20160279251A1 (en) * 2013-11-12 2016-09-29 University Of Washington Through Its Center For Commercialization Random copolymer therapeutic agent carriers and assemblies thereof
CN105885027A (en) * 2015-01-26 2016-08-24 中国科学院上海药物研究所 PEG modified polymyxin and preparation method and application thereof
MD4482C1 (en) * 2016-12-23 2017-12-31 Государственный Университет Молд0 Process for conjugating alpha-glucans with streptomycin
WO2019104213A1 (en) * 2017-11-22 2019-05-31 Board Of Regents, The University Of Texas System Antibiofilm formulations and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7702261L (en) * 1976-03-02 1977-09-07 Pharmaco Inc PROCEDURE FOR IMMOBILIZING THE ANTIMICROBIAL SUBJECT
DE3676670D1 (en) * 1985-06-26 1991-02-07 Cetus Corp SOLUBILIZATION OF PROTEINS FOR PHARMACEUTICAL COMPOSITIONS BY POLYMER CONJUGATION.

Also Published As

Publication number Publication date
CA2018833A1 (en) 1990-12-14
WO1990015628A1 (en) 1990-12-27

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