AU5503399A - Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies - Google Patents
Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergiesInfo
- Publication number
- AU5503399A AU5503399A AU55033/99A AU5503399A AU5503399A AU 5503399 A AU5503399 A AU 5503399A AU 55033/99 A AU55033/99 A AU 55033/99A AU 5503399 A AU5503399 A AU 5503399A AU 5503399 A AU5503399 A AU 5503399A
- Authority
- AU
- Australia
- Prior art keywords
- acid
- derivatives
- bisphosphonic
- autoimmune diseases
- bisphosphonic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The invention relates to the use of bisphosphonic acids and the derivatives thereof for producing medicaments for preventing and treating autoimmune diseases or allergies combined with the autoantigens specifically used for treating the respective autoimmune disease or combined with the allergens specifically used for treating the respective allergy. Some examples of the bisphosphonic acids or derivatives thereof which are used according to the invention include amino-hydroxy-methylidene-bisphosphonic acid (AMP), 2-amino-1-hydroxyethylidene-1,1-bisphosphonic acid (AEP), pamidronic acid, alendronic acid, 6-amino-1-hydroxyhexylidene-1,1-bisphosphonic acid (AHP), amidinomethylene-bisphosphonic acid (AIMP), ibandronic acid, risedronic acid, zoledronic acid, cimadronic acid, and tiludronic acid. Some examples of autoimmune diseases in which bisphosphonic acids or the derivatives thereof can be used include rheumatoid arthritis, severe myasthenia, diabetes mellitus, uveitis, and scleroderma. The bisphosphonic acids or the derivatives thereof and the autoantigens or allergens can be applied simultaneously or in succession. The preparations of the combinations can be used in solid form, as ointments, as solutions or as sprays.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19828450A DE19828450A1 (en) | 1998-06-26 | 1998-06-26 | Use of bisphosphonic acid compounds and autoantigens or allergens |
| DE19828450 | 1998-06-26 | ||
| PCT/DE1999/001844 WO2000000182A2 (en) | 1998-06-26 | 1999-06-24 | Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU5503399A true AU5503399A (en) | 2000-01-17 |
| AU740605B2 AU740605B2 (en) | 2001-11-08 |
Family
ID=7872064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU55033/99A Ceased AU740605B2 (en) | 1998-06-26 | 1999-06-24 | Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1089761B1 (en) |
| JP (1) | JP2002519319A (en) |
| KR (1) | KR20010053211A (en) |
| AT (1) | ATE224734T1 (en) |
| AU (1) | AU740605B2 (en) |
| CA (1) | CA2334711C (en) |
| DE (2) | DE19828450A1 (en) |
| DK (1) | DK1089761T3 (en) |
| EA (1) | EA200100080A1 (en) |
| EE (1) | EE200000756A (en) |
| ES (1) | ES2184496T3 (en) |
| HR (1) | HRP20000820A2 (en) |
| HU (1) | HUP0102873A3 (en) |
| ID (1) | ID27515A (en) |
| IL (1) | IL139966A0 (en) |
| IS (1) | IS5748A (en) |
| MX (1) | MXPA00012338A (en) |
| NO (1) | NO20006572L (en) |
| NZ (1) | NZ509505A (en) |
| PL (1) | PL345287A1 (en) |
| PT (1) | PT1089761E (en) |
| SK (1) | SK19602000A3 (en) |
| TR (1) | TR200003821T2 (en) |
| WO (1) | WO2000000182A2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE253368T1 (en) * | 1998-12-23 | 2003-11-15 | Bioagency Ag | USE OF BISPHOSPHONATES FOR PROPHYLAXIS AND TREATMENT OF INFECTIOUS PROCESSES |
| CA2321864A1 (en) * | 1998-12-25 | 2000-07-06 | Toray Industries, Inc. | Interleukin-6 production inhibitor |
| CA2444718A1 (en) * | 2001-05-02 | 2002-11-14 | Novartis Ag | Method of administration of bisphosphonates by inhalation in the treatment or prevention of bone resorption and osteoporosis |
| ES2315411T3 (en) | 2001-07-20 | 2009-04-01 | Bioagency Ag | ORGANOFOSPHORATED COMPOUNDS FOR THE ACTIVATION OF T GAMMA / DELTA CELLS. |
| GB0307989D0 (en) * | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
| EP1713489B1 (en) * | 2004-08-23 | 2011-01-19 | Teva Pharmaceutical Industries Ltd | Crystalline form of ibandronate sodium and processes for preparation thereof |
| CN101262856A (en) * | 2005-09-12 | 2008-09-10 | 雷迪博士实验室有限公司 | Crystalline trihydrate of zoledronic acid |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993005052A1 (en) * | 1991-09-05 | 1993-03-18 | Toray Industries, Inc. | Methanediphosphonic acid derivative, production thereof and medicinal use thereof |
| DE69622157T2 (en) * | 1995-01-23 | 2003-03-13 | Xenotech Inc., Fremont | COMPOSITION TO PREVENT OSTEOLYSIS AND METASTASES |
-
1998
- 1998-06-26 DE DE19828450A patent/DE19828450A1/en not_active Withdrawn
-
1999
- 1999-06-24 PL PL99345287A patent/PL345287A1/en unknown
- 1999-06-24 AT AT99941383T patent/ATE224734T1/en active
- 1999-06-24 EP EP99941383A patent/EP1089761B1/en not_active Expired - Lifetime
- 1999-06-24 CA CA002334711A patent/CA2334711C/en not_active Expired - Fee Related
- 1999-06-24 JP JP2000556767A patent/JP2002519319A/en active Pending
- 1999-06-24 DE DE59902856T patent/DE59902856D1/en not_active Expired - Lifetime
- 1999-06-24 KR KR1020007014813A patent/KR20010053211A/en not_active Ceased
- 1999-06-24 MX MXPA00012338A patent/MXPA00012338A/en unknown
- 1999-06-24 TR TR2000/03821T patent/TR200003821T2/en unknown
- 1999-06-24 HU HU0102873A patent/HUP0102873A3/en unknown
- 1999-06-24 NZ NZ509505A patent/NZ509505A/en not_active IP Right Cessation
- 1999-06-24 PT PT99941383T patent/PT1089761E/en unknown
- 1999-06-24 EE EEP200000756A patent/EE200000756A/en unknown
- 1999-06-24 HR HR20000820A patent/HRP20000820A2/en not_active Application Discontinuation
- 1999-06-24 WO PCT/DE1999/001844 patent/WO2000000182A2/en not_active Ceased
- 1999-06-24 AU AU55033/99A patent/AU740605B2/en not_active Ceased
- 1999-06-24 IL IL13996699A patent/IL139966A0/en unknown
- 1999-06-24 SK SK1960-2000A patent/SK19602000A3/en unknown
- 1999-06-24 ES ES99941383T patent/ES2184496T3/en not_active Expired - Lifetime
- 1999-06-24 EA EA200100080A patent/EA200100080A1/en unknown
- 1999-06-24 DK DK99941383T patent/DK1089761T3/en active
- 1999-06-24 ID IDW20002676A patent/ID27515A/en unknown
-
2000
- 2000-12-01 IS IS5748A patent/IS5748A/en unknown
- 2000-12-21 NO NO20006572A patent/NO20006572L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20006572D0 (en) | 2000-12-21 |
| PT1089761E (en) | 2003-02-28 |
| JP2002519319A (en) | 2002-07-02 |
| DE19828450A1 (en) | 1999-12-30 |
| SK19602000A3 (en) | 2001-07-10 |
| WO2000000182A2 (en) | 2000-01-06 |
| IS5748A (en) | 2000-12-01 |
| DE59902856D1 (en) | 2002-10-31 |
| NZ509505A (en) | 2002-11-26 |
| TR200003821T2 (en) | 2001-06-21 |
| KR20010053211A (en) | 2001-06-25 |
| DK1089761T3 (en) | 2003-02-03 |
| WO2000000182A3 (en) | 2000-03-30 |
| HUP0102873A3 (en) | 2002-04-29 |
| HRP20000820A2 (en) | 2001-12-31 |
| PL345287A1 (en) | 2001-12-03 |
| EP1089761A2 (en) | 2001-04-11 |
| CA2334711C (en) | 2006-12-05 |
| HUP0102873A2 (en) | 2001-12-28 |
| EP1089761B1 (en) | 2002-09-25 |
| IL139966A0 (en) | 2002-02-10 |
| NO20006572L (en) | 2001-02-21 |
| MXPA00012338A (en) | 2003-04-25 |
| ES2184496T3 (en) | 2003-04-01 |
| EA200100080A1 (en) | 2001-06-25 |
| AU740605B2 (en) | 2001-11-08 |
| CA2334711A1 (en) | 2000-01-06 |
| ATE224734T1 (en) | 2002-10-15 |
| ID27515A (en) | 2001-04-12 |
| EE200000756A (en) | 2002-04-15 |
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| MXPA02009924A (en) | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced gi toxicity. | |
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| NO20003674D0 (en) | Solid pharmaceutical preparations containing spleen phosin for oral administration in the treatment of Leishmaniase | |
| CA2024694A1 (en) | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors | |
| ES2152865A1 (en) | Use of bisphosphonates in pharmaceutical preparations intended for intramuscular use | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| PC | Assignment registered |
Owner name: JOMAA PHARMAKA GMBH Free format text: FORMER OWNER WAS: HASSAN JOMAA |
|
| PC | Assignment registered |
Owner name: BIOAGENCY AG Free format text: FORMER OWNER WAS: JOMAA PHARMAKA GMBH |