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AU5346299A - Du site-directed cleavage of covalent conjugates - Google Patents

Du site-directed cleavage of covalent conjugates

Info

Publication number
AU5346299A
AU5346299A AU53462/99A AU5346299A AU5346299A AU 5346299 A AU5346299 A AU 5346299A AU 53462/99 A AU53462/99 A AU 53462/99A AU 5346299 A AU5346299 A AU 5346299A AU 5346299 A AU5346299 A AU 5346299A
Authority
AU
Australia
Prior art keywords
site
directed cleavage
covalent conjugates
conjugates
covalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU53462/99A
Inventor
Russ Lehrman
Stephanie Niewlandt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Publication of AU5346299A publication Critical patent/AU5346299A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU53462/99A 1998-08-26 1999-08-10 Du site-directed cleavage of covalent conjugates Abandoned AU5346299A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14009998A 1998-08-26 1998-08-26
US09140099 1998-08-26
PCT/US1999/018091 WO2000012530A1 (en) 1998-08-26 1999-08-10 dU SITE-DIRECTED CLEAVAGE OF COVALENT CONJUGATES

Publications (1)

Publication Number Publication Date
AU5346299A true AU5346299A (en) 2000-03-21

Family

ID=22489752

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53462/99A Abandoned AU5346299A (en) 1998-08-26 1999-08-10 Du site-directed cleavage of covalent conjugates

Country Status (2)

Country Link
AU (1) AU5346299A (en)
WO (1) WO2000012530A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5209204B2 (en) 2003-04-13 2013-06-12 エンゾン ファーマスーティカルズ インコーポレイテッド Polymer oligonucleotide prodrug
US9506897B2 (en) 2012-11-16 2016-11-29 Agilent Technologies, Inc. Methods and compositions for improved ion-exchange chromatography
CN108676130B (en) * 2018-06-06 2020-08-14 河南师范大学 Reduction-responsive core-crosslinked polymers for drug carriers MPEG-NSASSPreparation of-Chol micelles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0537299A1 (en) * 1990-03-29 1993-04-21 Gilead Sciences, Inc. Oligonucleotide-transport agent disulfide conjugates
US5660985A (en) * 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US6521601B1 (en) * 1992-04-14 2003-02-18 Signal Pharmaceuticals, Inc. Method and composition for inhibition of viral replication
US5723594A (en) * 1995-06-07 1998-03-03 Nexstar Pharmaceuticals, Inc. High affinity PDGF nucleic acid ligands

Also Published As

Publication number Publication date
WO2000012530A1 (en) 2000-03-09

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase