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AU5282200A - Methods of reducing factor viii clearance and compositions therefor - Google Patents

Methods of reducing factor viii clearance and compositions therefor

Info

Publication number
AU5282200A
AU5282200A AU52822/00A AU5282200A AU5282200A AU 5282200 A AU5282200 A AU 5282200A AU 52822/00 A AU52822/00 A AU 52822/00A AU 5282200 A AU5282200 A AU 5282200A AU 5282200 A AU5282200 A AU 5282200A
Authority
AU
Australia
Prior art keywords
methods
factor viii
compositions therefor
reducing factor
viii clearance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU52822/00A
Other languages
English (en)
Inventor
Evgueni L. Saenko
Dudley K. Strickland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Original Assignee
American National Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross filed Critical American National Red Cross
Publication of AU5282200A publication Critical patent/AU5282200A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU52822/00A 1999-05-24 2000-05-24 Methods of reducing factor viii clearance and compositions therefor Abandoned AU5282200A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13584799P 1999-05-24 1999-05-24
US60135847 1999-05-24
PCT/US2000/014111 WO2000071714A2 (fr) 1999-05-24 2000-05-24 Procedes de reduction de la clairance du facteur viii et compositions correspondantes

Publications (1)

Publication Number Publication Date
AU5282200A true AU5282200A (en) 2000-12-12

Family

ID=22469983

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52822/00A Abandoned AU5282200A (en) 1999-05-24 2000-05-24 Methods of reducing factor viii clearance and compositions therefor

Country Status (3)

Country Link
EP (1) EP1183354A2 (fr)
AU (1) AU5282200A (fr)
WO (1) WO2000071714A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794493B2 (en) 2000-04-07 2004-09-21 Wisys Technology Foundation, Inc. Antithrombin H-helix mutants
AU2002248329B2 (en) * 2001-01-12 2007-06-28 The American National Red Cross Methods and compositions for reducing heparan sulfate proteoglycan-mediated clearance of factor VIII
ATE445838T1 (de) * 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP1454916A1 (fr) * 2002-11-29 2004-09-08 ZLB Behring GmbH ADNc modifié du facteur VIII et dérivés
EP1424344A1 (fr) * 2002-11-29 2004-06-02 Aventis Behring Gesellschaft mit beschränkter Haftung ADNc modifié du facteur VIII et dérivés
EP1444986A1 (fr) * 2003-02-07 2004-08-11 Aventis Behring GmbH Preparation pharmaceutique pour l'amélioration du traitement des maladies liées à une coagulation sanguine diminuée
EP1454632A1 (fr) * 2003-02-07 2004-09-08 Aventis Behring GmbH, Intellectual Property/Legal Composé pharmaceutique contenant des peptides dérivés du facteur VIII pour le traitement de troubles de la coagulation sanguine
US20050026823A1 (en) 2003-06-20 2005-02-03 Biomarin Pharmaceutical Inc. Use of the chaperone receptor-associated protein (RAP) for the delivery of therapeutic compounds to the brain and other tissues
EP1502921A1 (fr) * 2003-07-29 2005-02-02 ZLB Behring GmbH Mutants du Facteur VIII (FVIII) humain recombinants ayant une meilleure stabilité
US7211559B2 (en) 2003-10-31 2007-05-01 University Of Maryland, Baltimore Factor VIII compositions and methods
HRP20070268B1 (hr) 2004-11-12 2018-04-20 Bayer Healthcare Llc Ciljana modifikacija faktora viii
US20080227691A1 (en) * 2005-04-01 2008-09-18 Novo Nordisk Health Care Ag Blood Coagulation FVIII Analogues
US20110124565A1 (en) * 2005-04-14 2011-05-26 Hans-Peter Hauser Modified Coagulation Factor VIII With Enhanced Stability and Its Derivatives
WO2006138343A2 (fr) * 2005-06-14 2006-12-28 Raptor Pharmaceutical Inc. Compositions comprenant des variants de proteine associee au recepteur (rap) specifiques a lrp2, et utilisations correspondantes
WO2007035716A2 (fr) * 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions de proteines rap specifiques des proteines contenant du cr, et leurs utilisations
EP1816201A1 (fr) 2006-02-06 2007-08-08 CSL Behring GmbH Facteur de coagulation VIIa modifié ayant une stabilité 'half-life' améliorée
EP2097096B1 (fr) * 2006-12-22 2017-05-31 CSL Behring GmbH Facteurs de coagulation modifiés avec une demi-vie in vivo prolongée
EP1935430A1 (fr) * 2006-12-22 2008-06-25 CSL Behring GmbH Facteurs de coagulation modifiés avec une demi-vie in vivo prolongée
WO2015132724A1 (fr) 2014-03-05 2015-09-11 Pfizer Inc. Mutéines améliorées du facteur viii de coagulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5859204A (en) 1992-04-07 1999-01-12 Emory University Modified factor VIII
AU1382595A (en) * 1994-01-07 1995-08-01 Novo Nordisk A/S Factor viii derivatives
US5650391A (en) * 1994-03-21 1997-07-22 Jewish Hospital Of St. Louis Methods and compositions for inhibition of hepatic clearance of tissue factor pathway inhibitor
AU6486196A (en) 1995-07-11 1997-02-10 Chiron Corporation Novel factor viii:c polypeptide analogs with altered protease sites
AT403438B (de) * 1996-05-24 1998-02-25 Immuno Ag Pharmazeutische präparation mit faktor viii prokoagulationsaktivität und vwf-bindungsaktivität
AT409335B (de) * 1998-11-10 2002-07-25 Immuno Ag Pharmazeutisches präparat enthaltend einen rezeptor-antagonisten zur behandlung von blutgerinnungsstörungen
ES2292255T5 (es) * 1998-11-10 2017-05-19 Stichting Sanquin Bloedvoorziening Polipéptido del factor 8 con actividad de factor 8:C

Also Published As

Publication number Publication date
WO2000071714A3 (fr) 2001-01-18
WO2000071714A2 (fr) 2000-11-30
EP1183354A2 (fr) 2002-03-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase