[go: up one dir, main page]

AU5110096A - Process for the production of combinatorial compound libraries - Google Patents

Process for the production of combinatorial compound libraries

Info

Publication number
AU5110096A
AU5110096A AU51100/96A AU5110096A AU5110096A AU 5110096 A AU5110096 A AU 5110096A AU 51100/96 A AU51100/96 A AU 51100/96A AU 5110096 A AU5110096 A AU 5110096A AU 5110096 A AU5110096 A AU 5110096A
Authority
AU
Australia
Prior art keywords
production
compound libraries
combinatorial compound
combinatorial
libraries
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU51100/96A
Inventor
Eduard Felder
Bertold Gercken
Hans Rink
Dirk Vetter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU5110096A publication Critical patent/AU5110096A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
AU51100/96A 1995-03-28 1996-03-18 Process for the production of combinatorial compound libraries Abandoned AU5110096A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95810203 1995-03-28
EP95810203 1995-03-28
PCT/EP1996/001154 WO1996030392A1 (en) 1995-03-28 1996-03-18 Process for the production of combinatorial compound libraries

Publications (1)

Publication Number Publication Date
AU5110096A true AU5110096A (en) 1996-10-16

Family

ID=8221719

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51100/96A Abandoned AU5110096A (en) 1995-03-28 1996-03-18 Process for the production of combinatorial compound libraries

Country Status (4)

Country Link
AU (1) AU5110096A (en)
IL (1) IL117664A0 (en)
WO (1) WO1996030392A1 (en)
ZA (1) ZA962434B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU739256B2 (en) * 1996-04-08 2001-10-04 Glaxo Group Limited Mass-based encoding and qualitative analysis of combinatorial libraries
ES2288760T3 (en) 1996-04-25 2008-01-16 Bioarray Solutions Ltd. ELECTROCINETIC ASSEMBLY CONTROLLED BY LIGHT OF PARTICLES NEXT TO SURFACES.
GB9621985D0 (en) 1996-10-22 1996-12-18 Peptide Therapeutics Ltd A solid-phase technology for the preparation of libraries of bi-directally functionalised drug-like molecules
US5958703A (en) * 1996-12-03 1999-09-28 Glaxo Group Limited Use of modified tethers in screening compound libraries
AUPP032897A0 (en) * 1997-11-12 1997-12-04 University Of Queensland, The Oligomer libraries
EP2241542A1 (en) 1998-01-05 2010-10-20 Neogenesis, Inc. Apparatus for producing mass-coded combinatorial libraries
EP1728776A3 (en) * 1998-01-05 2006-12-13 Neogenesis, Inc. Method for identifying a member of a mass-coded combinatorial library
US6207861B1 (en) 1998-01-05 2001-03-27 Neogenesis, Inc. Method for producing and screening mass coded combinatorial libraries for drug discovery and target validation
EP2045334A1 (en) 1998-06-24 2009-04-08 Illumina, Inc. Decoding of array sensors with microspheres
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
EP1190100B1 (en) 1999-05-20 2012-07-25 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
US6544732B1 (en) 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
US8481268B2 (en) 1999-05-21 2013-07-09 Illumina, Inc. Use of microfluidic systems in the detection of target analytes using microsphere arrays
US8080380B2 (en) 1999-05-21 2011-12-20 Illumina, Inc. Use of microfluidic systems in the detection of target analytes using microsphere arrays
US7604996B1 (en) 1999-08-18 2009-10-20 Illumina, Inc. Compositions and methods for preparing oligonucleotide solutions
WO2001046675A2 (en) * 1999-12-23 2001-06-28 Illumina, Inc. Decoding of array sensors with microspheres
US6309889B1 (en) 1999-12-23 2001-10-30 Glaxo Wellcome Inc. Nano-grid micro reactor and methods
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
CA2399733C (en) 2000-02-07 2011-09-20 Illumina, Inc. Nucleic acid detection methods using universal priming
US7361488B2 (en) 2000-02-07 2008-04-22 Illumina, Inc. Nucleic acid detection methods using universal priming
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
AU3806701A (en) 2000-02-07 2001-08-14 Illumina Inc Nucleic acid detection methods using universal priming
DE60136335D1 (en) 2000-02-16 2008-12-11 Illumina Inc PARALLEL GENOTYPING OF SEVERAL PATIENT SAMPLES
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
CA2635452A1 (en) 2000-06-21 2001-12-27 Bioarray Solutions, Ltd. Looped probe design to control hybridization stringency
WO2002003067A1 (en) * 2000-07-03 2002-01-10 Merck & Co., Inc. Methods for encoding combinatorial libraries
US6576472B1 (en) 2000-07-26 2003-06-10 Smithkline Beecham Corporation Chemical constructs for solution phase chemistry
US6584411B1 (en) 2000-07-26 2003-06-24 Smithkline Beecham Corporation Methods to facilitate the calculation of yields of reaction products
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
IL161391A0 (en) 2001-10-15 2004-09-27 Bioarray Solutions Ltd Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
AU2002349905A1 (en) * 2001-12-17 2003-06-30 Ribapharm Inc. Nucleoside libraries and compounds by mcc combinatorial strategies on solid support
US7335153B2 (en) 2001-12-28 2008-02-26 Bio Array Solutions Ltd. Arrays of microparticles and methods of preparation thereof
US7041453B2 (en) 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
ES2375962T3 (en) 2003-09-22 2012-03-07 Bioarray Solutions Ltd IMMOBILIZED SURFACE POLYELECTROLYTE WITH MULTIPLE FUNCTIONAL GROUPS ABLE TO JOIN COVALENTLY TO BIOMOLECULES.
JP2007521017A (en) 2003-10-28 2007-08-02 バイオアレイ ソリューションズ リミテッド Optimization of gene expression analysis using immobilized capture probes
US7622281B2 (en) 2004-05-20 2009-11-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for clonal amplification of nucleic acid
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
KR100310939B1 (en) * 1992-10-01 2002-06-20 추후제출 Complex Combination Chemistry Library Encrypted with Tags
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
JPH09508355A (en) * 1993-12-09 1997-08-26 チバ−ガイギー アクチェンゲゼルシャフト How to make a combinatorial compound library

Also Published As

Publication number Publication date
WO1996030392A1 (en) 1996-10-03
ZA962434B (en) 1996-09-30
IL117664A0 (en) 1996-07-23

Similar Documents

Publication Publication Date Title
AU5110096A (en) Process for the production of combinatorial compound libraries
AU7062496A (en) Process for the production of Bis(silyalkyl)-disulfanes
AU1021097A (en) Improved process for the synthesis of oligomeric compounds
AU698339B2 (en) Novel catalysts for the production of polyolefins
HU9601588D0 (en) Process for the production of combinatorial compound libraries
AU4352896A (en) Process for the production of methanol
HUP9901285A3 (en) Process for the production of difluoromethane
AU4631596A (en) Process for the microbiological production of pha-polymers
AU5871196A (en) Methods and compounds for the synthesis of oligonucleotides and the oligonucleotides thereby produced
HUP9900897A3 (en) Process for the production of cesium compounds
AU5728496A (en) Method of forming articles of manufacture
GR3032600T3 (en) Process for the production of imidazo-benzodiazepine derivatives
AU7522596A (en) Synthesis of substituted n-heteroaromatic compounds by combinatorial chemistry
AU6707396A (en) Processes for the production of amidase
AU5627296A (en) Process for the manufacture of difluoromethane
AU6386196A (en) Process for parallel synthesis of a non-peptide library
AU4652296A (en) Methods for production of large catalogued chemical libraries
AU4424496A (en) A method for the synthesis of mixtures of compounds
AU6871996A (en) Process for the production of water-absorbing compositions
AU665710B2 (en) Process for the production of synthesis gas
AU4675996A (en) Process for producing indoline compounds and intermediates for the production of the same
AU1093197A (en) Combinatorial libraries
AU5797098A (en) Combinatorial process for preparing hydrofuroquinoline libraries
SG38905A1 (en) Process for the manufacture of hydroxyalkoxybenzophenones
AU6724696A (en) Improved process for the production of amphotericin-b