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AU5100599A - Egf-genistein for prevention of restenosis - Google Patents

Egf-genistein for prevention of restenosis

Info

Publication number
AU5100599A
AU5100599A AU51005/99A AU5100599A AU5100599A AU 5100599 A AU5100599 A AU 5100599A AU 51005/99 A AU51005/99 A AU 51005/99A AU 5100599 A AU5100599 A AU 5100599A AU 5100599 A AU5100599 A AU 5100599A
Authority
AU
Australia
Prior art keywords
genistein
restenosis
egf
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU51005/99A
Inventor
Vuong N. Trieu
Fatih M. Uckun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parker Hughes Institute
Original Assignee
Howard Hughes Medical Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howard Hughes Medical Institute filed Critical Howard Hughes Medical Institute
Publication of AU5100599A publication Critical patent/AU5100599A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1808—Epidermal growth factor [EGF] urogastrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU51005/99A 1998-07-13 1999-07-13 Egf-genistein for prevention of restenosis Abandoned AU5100599A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09114680 1998-07-13
US09/114,680 US6034053A (en) 1998-07-13 1998-07-13 EGF-isoflavone conjugates for the prevention of restenosis
PCT/US1999/015881 WO2000002576A2 (en) 1998-07-13 1999-07-13 Egf-genistein for prevention of restenosis

Publications (1)

Publication Number Publication Date
AU5100599A true AU5100599A (en) 2000-02-01

Family

ID=22356768

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51005/99A Abandoned AU5100599A (en) 1998-07-13 1999-07-13 Egf-genistein for prevention of restenosis

Country Status (3)

Country Link
US (1) US6034053A (en)
AU (1) AU5100599A (en)
WO (1) WO2000002576A2 (en)

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US7390668B2 (en) * 1996-10-30 2008-06-24 Provectus Pharmatech, Inc. Intracorporeal medicaments for photodynamic treatment of disease
DE10003521A1 (en) * 2000-01-27 2001-08-09 Medigene Ag Device for producing a three-dimensional matrix body, multi-well plate, solution for cultivating mammalian cardiomyocytes, method for culturing a cell culture, device for measuring isometric force parameters of cell cultures and method for measurably tracking contractions of a cell tissue embedded in a carrier substance
JP2002161049A (en) * 2000-11-28 2002-06-04 Terumo Corp Intimal thickening inhibitor
US20050119301A1 (en) * 2001-03-16 2005-06-02 Alan Husband Treatment of restenosis
US20030181510A1 (en) * 2002-03-19 2003-09-25 Robert Baker Inhibition of muscle regeneration following myectomy
US7425618B2 (en) 2002-06-14 2008-09-16 Medimmune, Inc. Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
JP4596916B2 (en) * 2002-09-05 2010-12-15 メディミューン，エルエルシー Method for preventing or treating T cell malignancies by administering a CD2 antagonist
US8034831B2 (en) * 2002-11-06 2011-10-11 Celgene Corporation Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
US7563810B2 (en) * 2002-11-06 2009-07-21 Celgene Corporation Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
WO2004091510A2 (en) 2003-04-11 2004-10-28 Medimmune, Inc. Recombinant il-9 antibodies and uses thereof
US20060228350A1 (en) * 2003-08-18 2006-10-12 Medimmune, Inc. Framework-shuffling of antibodies
WO2005042743A2 (en) 2003-08-18 2005-05-12 Medimmune, Inc. Humanization of antibodies
EP1809326A4 (en) 2004-10-27 2009-11-04 Medimmune Inc Modulation of antibody specificity by tailoring the affinity to cognate antigens
WO2006102095A2 (en) 2005-03-18 2006-09-28 Medimmune, Inc. Framework-shuffling of antibodies
US20070110757A1 (en) 2005-06-23 2007-05-17 Ziping Wei Antibody formulations having optimized aggregation and fragmentation profiles
DE102006038241A1 (en) * 2006-08-07 2008-02-14 Biotronik Vi Patent Ag Stent with a genisteinhaltigen coating or Kavitätenfüllung
EP2064243A2 (en) 2006-08-28 2009-06-03 Kyowa Hakko Kirin Co., Ltd. Antagonistic human light-specific human monoclonal antibodies
CA2682170A1 (en) 2007-03-30 2008-10-09 Medimmune, Llc Antibodies with decreased deamidation profiles
WO2009029601A2 (en) 2007-08-24 2009-03-05 Regents Of The University Of Minnesota Receptor-targeting reagents
RS62853B1 (en) 2010-01-06 2022-02-28 Takeda Pharmaceuticals Co Plasma kallikrein binding proteins
US9540443B2 (en) 2011-01-26 2017-01-10 Kolltan Pharmaceuticals, Inc. Anti-kit antibodies
TWI596113B (en) 2012-07-25 2017-08-21 塞爾德克斯醫療公司 anti-KIT antibody and use thereof
WO2014059028A1 (en) 2012-10-09 2014-04-17 Igenica, Inc. Anti-c16orf54 antibodies and methods of use thereof
CN103275052A (en) * 2013-05-24 2013-09-04 陕西师范大学 Method for synthesizing isoflavone by nickel-catalyzed Negishi cross coupling reaction at room temperature
SG11201509982UA (en) 2013-06-06 2016-04-28 Igenica Biotherapeutics Inc
EP3041507B1 (en) 2013-08-26 2021-06-30 BioNTech Research and Development, Inc. Nucleic acids encoding human antibodies to sialyl-lewis a
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
AU2015271685B2 (en) 2014-06-04 2021-02-18 Biontech Research And Development, Inc. Human monoclonal antibodies to ganglioside GD2
WO2016094837A2 (en) 2014-12-11 2016-06-16 Igenica Biotherapeutics, Inc. Anti-c10orf54 antibodies and uses thereof
DE112016001013T5 (en) 2015-03-03 2017-12-21 Kymab Limited ANTIBODIES, USES AND METHODS
JP7227007B2 (en) 2015-12-02 2023-02-21 ストサイエンシス， インコーポレイテッド Antibodies specific for glycosylated BTLA (B- and T-lymphocyte-attenuating factor)
EP3909983A1 (en) 2015-12-02 2021-11-17 STCube & Co. Inc. Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
US11779604B2 (en) 2016-11-03 2023-10-10 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses and methods
KR102861670B1 (en) 2017-05-31 2025-09-18 주식회사 에스티큐브앤컴퍼니 Methods for treating cancer using antibodies and molecules that immunospecifically bind to BTN1A1
EP3630835A1 (en) 2017-05-31 2020-04-08 STCube & Co., Inc. Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
JP2020522562A (en) 2017-06-06 2020-07-30 ストキューブ アンド シーオー．， インコーポレイテッド Methods of treating cancer with antibodies and molecules that bind to BTN1A1 or BTN1A1 ligand
US11707522B2 (en) 2017-10-13 2023-07-25 Boehringer Ingelheim International Gmbh Human antibodies to Tn antigen
MA53160A (en) 2018-07-20 2021-05-26 Pf Medicament RECEIVER FOR VISTA

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654307A (en) * 1994-01-25 1997-08-05 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
US5911995A (en) * 1994-08-19 1999-06-15 Regents Of The University Of Minnesota EGF-genistein conjugates for the treatment of cancer
US5587459A (en) * 1994-08-19 1996-12-24 Regents Of The University Of Minnesota Immunoconjugates comprising tyrosine kinase inhibitors

Also Published As

Publication number Publication date
WO2000002576A2 (en) 2000-01-20
WO2000002576A3 (en) 2000-03-30
US6034053A (en) 2000-03-07
WO2000002576A9 (en) 2000-05-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase