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AU4518279A - Prostacyclin analogues - Google Patents

Prostacyclin analogues

Info

Publication number
AU4518279A
AU4518279A AU45182/79A AU4518279A AU4518279A AU 4518279 A AU4518279 A AU 4518279A AU 45182/79 A AU45182/79 A AU 45182/79A AU 4518279 A AU4518279 A AU 4518279A AU 4518279 A AU4518279 A AU 4518279A
Authority
AU
Australia
Prior art keywords
prostacyclin analogues
prostacyclin
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU45182/79A
Inventor
Wilhelm Bartmann
Elmar Konz
Ulrich Lerch
Bernward Scholkens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4518279A publication Critical patent/AU4518279A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU45182/79A 1978-03-18 1979-03-16 Prostacyclin analogues Abandoned AU4518279A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782811950 DE2811950A1 (en) 1978-03-18 1978-03-18 NEW PROSTACYCLIN ANALOGS
DE28119508 1978-03-18

Publications (1)

Publication Number Publication Date
AU4518279A true AU4518279A (en) 1979-09-20

Family

ID=6034863

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45182/79A Abandoned AU4518279A (en) 1978-03-18 1979-03-16 Prostacyclin analogues

Country Status (7)

Country Link
EP (1) EP0004335A3 (en)
JP (1) JPS54130558A (en)
AU (1) AU4518279A (en)
DE (1) DE2811950A1 (en)
ES (1) ES478530A1 (en)
IL (1) IL56892A0 (en)
ZA (1) ZA791266B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648556A5 (en) * 1981-03-11 1985-03-29 Hoffmann La Roche FLUORPROSTACYCLINE.
JPS6028943A (en) * 1983-07-26 1985-02-14 Sankyo Co Ltd Carbacyclin analog
CN101903324B (en) 2007-12-17 2013-07-03 联合治疗公司 An improved method for preparing the active ingredient Treprostinil in Remodulin
US8481782B2 (en) * 2010-06-03 2013-07-09 United Therapeutics Corporation Treprostinil production
EP2681204B1 (en) 2011-03-02 2016-04-27 United Therapeutics Corporation Synthesis of intermediate for treprostinil production
EP3209415B1 (en) 2014-10-20 2020-02-19 United Therapeutics Corporation Synthesis of intermediates for producing prostacyclin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
FR2351113A1 (en) * 1976-05-11 1977-12-09 Wellcome Found PROSTAGLANDIN DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING SUCH DERIVATIVES
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
MX4813E (en) * 1976-06-01 1982-10-19 Upjohn Co PROCEDURE FOR PREPARING ANALOGS OF PROSTAGLANDINAS
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
IT1098350B (en) * 1977-07-28 1985-09-07 Upjohn Co PROSTAGLANDINIC DERIVATIVES
DE2743283A1 (en) * 1977-09-27 1979-04-05 Hoechst Ag NEW PROSTACYCLIN ANALOG

Also Published As

Publication number Publication date
ZA791266B (en) 1980-03-26
IL56892A0 (en) 1979-05-31
EP0004335A3 (en) 1979-11-28
EP0004335A2 (en) 1979-10-03
DE2811950A1 (en) 1979-12-13
ES478530A1 (en) 1979-11-01
JPS54130558A (en) 1979-10-09

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