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AU4494399A - Inhibitors of androgen-independent activation of androgen receptor - Google Patents

Inhibitors of androgen-independent activation of androgen receptor

Info

Publication number
AU4494399A
AU4494399A AU44943/99A AU4494399A AU4494399A AU 4494399 A AU4494399 A AU 4494399A AU 44943/99 A AU44943/99 A AU 44943/99A AU 4494399 A AU4494399 A AU 4494399A AU 4494399 A AU4494399 A AU 4494399A
Authority
AU
Australia
Prior art keywords
androgen
inhibitors
independent activation
receptor
androgen receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44943/99A
Inventor
Nicholas Bruchovsky
Peter W. Gout
Nasrin R. Mawji
Marianne D. Sadar
Robert Snoek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of AU4494399A publication Critical patent/AU4494399A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU44943/99A 1998-06-30 1999-06-30 Inhibitors of androgen-independent activation of androgen receptor Abandoned AU4494399A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9187198P 1998-06-30 1998-06-30
US60091871 1998-06-30
PCT/CA1999/000604 WO2000001813A2 (en) 1998-06-30 1999-06-30 Peptide inhibitors of androgen-independent activation of androgen receptor

Publications (1)

Publication Number Publication Date
AU4494399A true AU4494399A (en) 2000-01-24

Family

ID=22230037

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44943/99A Abandoned AU4494399A (en) 1998-06-30 1999-06-30 Inhibitors of androgen-independent activation of androgen receptor

Country Status (3)

Country Link
AU (1) AU4494399A (en)
CA (1) CA2302169A1 (en)
WO (1) WO2000001813A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0111298A (en) 2000-06-28 2005-05-10 Bristol Myers Squibb Co Selective androgen receptor modulators and methods for their identification, design and use
JP2003018987A (en) * 2001-06-25 2003-01-21 Okazaki National Research Institutes Transgenic cells and methods for detecting disruptors using the same
US20100189776A1 (en) 2007-03-16 2010-07-29 Cancer Research Technology Ltd Anti-androgen peptides and uses thereof in cancer therapy
WO2009033212A1 (en) * 2007-09-11 2009-03-19 Christopher Hovens The use of estrogen and androgen binding proteins in methods and compositions for treating gynaecological cancers
FR2938334A1 (en) * 2008-11-13 2010-05-14 Galderma Res & Dev MODULATORS OF ADFP IN THE TREATMENT OF ACNE, SEBORRHEA DERMATITIS OR HYPERSEBORRHEA
BRPI0913673A2 (en) 2008-07-02 2015-10-13 British Columbia Cancer Agency use of a compound, pharmaceutical composition, and method for modulating androgen receptor activity
RU2519948C2 (en) 2008-08-22 2014-06-20 Бритиш Коламбиа Кэнсер Эйдженси Бранч Low-molecular inhibitors of n-terminus activation of androgen receptor
WO2011082487A1 (en) 2010-01-06 2011-07-14 British Columbia Cancer Agency Branch Bisphenol derivatives and their use as androgen receptor activity modulators
EP2693875A4 (en) 2011-04-08 2014-10-22 British Columbia Cancer Agency BISPHENOL COMPOUNDS AND METHODS OF USE
WO2013028572A1 (en) 2011-08-19 2013-02-28 British Columbia Cancer Agency Branch Fluorinated bisphenol ether compounds and methods for their use
GB2496135B (en) 2011-11-01 2015-03-18 Valirx Plc Inhibitors of the interaction between a Src family kinase and an androgen receptor or estradiol receptor for treatment of endometriosis
US9365510B2 (en) 2012-04-16 2016-06-14 British Columbia Cancer Agency Branch Aziridine bisphenol ethers and related compounds and methods for their use
GB2513615A (en) 2013-05-01 2014-11-05 Cancer Rec Tech Ltd Medical use
JP6100439B2 (en) 2013-05-10 2017-03-22 ブリティッシュ コロンビア キャンサー エージェンシー ブランチ Ester derivatives of androgen receptor modulators and methods for their use
EP3044197B1 (en) 2013-09-09 2018-11-07 British Columbia Cancer Agency Branch Halogenated compounds for cancer imaging and treatment and methods for their use
US9682933B2 (en) 2014-05-30 2017-06-20 British Columbia Cancer Agency Branch Androgen receptor modulators and methods for their use
JP6884100B2 (en) 2015-01-13 2021-06-09 ブリティッシュ コロンビア キャンサー エージェンシー ブランチ Heterocyclic compounds for cancer imaging and treatment and how to use them
US10471023B2 (en) 2015-03-12 2019-11-12 British Columbia Cancer Agency Branch Bisphenol ether derivatives and methods for using the same
US20170298033A1 (en) 2016-04-15 2017-10-19 The University Of British Columbia Bisphenol derivatives and their use as androgen receptor activity modulators
JP7407592B2 (en) * 2016-08-08 2024-01-04 オリパス コーポレーション Androgen receptor antisense oligonucleotide
US11485713B2 (en) 2018-05-25 2022-11-01 Essa Pharma, Inc. Androgen receptor modulators and methods for their use
MX2021004427A (en) 2018-10-18 2021-11-12 Univ British Columbia Androgen receptor modulators and methods for their use.
WO2020198712A1 (en) 2019-03-28 2020-10-01 Essa Pharma, Inc. Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof
JP2023522040A (en) 2020-04-17 2023-05-26 エッサ ファーマ，インコーポレイテッド Solid forms of N-terminal domain androgen receptor inhibitors and uses thereof
WO2023046283A1 (en) 2021-09-22 2023-03-30 Fundació Institut De Recerca Biomèdica (Irb Barcelona) Compounds and their use in a method for modulating ar (androgen receptor) transcriptional activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307030B1 (en) * 1988-04-15 2001-10-23 The University Of North Carolina At Chapel Hill Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions
EP0577932A3 (en) * 1992-05-08 1995-04-19 American Cyanamid Co Development of a "screening" for the detection of androgenic receptor agonists and antagonists.
US6184205B1 (en) * 1994-07-22 2001-02-06 University Of North Carolina At Chapel Hill GRB2 SH3 binding peptides and methods of isolating and using same

Also Published As

Publication number Publication date
WO2000001813A2 (en) 2000-01-13
WO2000001813A3 (en) 2000-04-13
CA2302169A1 (en) 2000-01-13

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase