[go: up one dir, main page]

AU4323599A - Compositions and methods for use in affecting hematopoietic stem cell populations in mammals - Google Patents

Compositions and methods for use in affecting hematopoietic stem cell populations in mammals

Info

Publication number
AU4323599A
AU4323599A AU43235/99A AU4323599A AU4323599A AU 4323599 A AU4323599 A AU 4323599A AU 43235/99 A AU43235/99 A AU 43235/99A AU 4323599 A AU4323599 A AU 4323599A AU 4323599 A AU4323599 A AU 4323599A
Authority
AU
Australia
Prior art keywords
mammals
compositions
methods
stem cell
hematopoietic stem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU43235/99A
Inventor
Cesare Peschle
Benedikt L. Ziegler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto Superiore di Sanita
Thomas Jefferson University
Original Assignee
Istituto Superiore di Sanita ISS
Instituto Superiore di Sanita
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Superiore di Sanita ISS, Instituto Superiore di Sanita, Thomas Jefferson University filed Critical Istituto Superiore di Sanita ISS
Publication of AU4323599A publication Critical patent/AU4323599A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/165—Vascular endothelial growth factor [VEGF]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU43235/99A 1998-05-29 1999-05-28 Compositions and methods for use in affecting hematopoietic stem cell populations in mammals Abandoned AU4323599A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8715398P 1998-05-29 1998-05-29
US60087153 1998-05-29
PCT/US1999/012054 WO1999061584A1 (en) 1998-05-29 1999-05-28 Compositions and methods for use in affecting hematopoietic stem cell populations in mammals

Publications (1)

Publication Number Publication Date
AU4323599A true AU4323599A (en) 1999-12-13

Family

ID=22203426

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43235/99A Abandoned AU4323599A (en) 1998-05-29 1999-05-28 Compositions and methods for use in affecting hematopoietic stem cell populations in mammals

Country Status (6)

Country Link
US (1) US6586192B1 (en)
EP (1) EP1084227A4 (en)
JP (1) JP2002516085A (en)
AU (1) AU4323599A (en)
CA (1) CA2330208A1 (en)
WO (1) WO1999061584A1 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1270719A3 (en) * 1998-08-24 2003-06-25 Viacell, Inc. Cell population containing non-fetal hemangioblasts and method for producing same
US6632620B1 (en) 2000-06-22 2003-10-14 Andrew N. Makarovskiy Compositions for identification and isolation of stem cells
ATE452910T1 (en) 2000-10-18 2010-01-15 Brigham & Womens Hospital E-SELECTIN/L-SELECTIN LIGAND POLYPEPTIDES OF HEMATOPOETIC CELLS AND METHOD FOR USE THEREOF
WO2004043990A2 (en) * 2002-11-07 2004-05-27 University Of Chicago Human stem cell materials and methods
JP4672370B2 (en) * 2002-12-05 2011-04-20 ケース ウエスタン リザーブ ユニバーシティ Cell-based treatment of ischemia
US7470538B2 (en) * 2002-12-05 2008-12-30 Case Western Reserve University Cell-based therapies for ischemia
CA2519975C (en) * 2003-04-08 2013-07-02 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
US7790458B2 (en) 2004-05-14 2010-09-07 Becton, Dickinson And Company Material and methods for the growth of hematopoietic stem cells
JP2008505650A (en) * 2004-07-12 2008-02-28 ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータ Apparatus and method for growing human cells
US9388382B2 (en) 2005-10-05 2016-07-12 The Board Of Trustees Of The University Of Illinois Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
CA2628712C (en) 2005-11-07 2014-02-11 Amorcyte, Inc. Compositions and methods of vascular injury repair
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
US20080050814A1 (en) * 2006-06-05 2008-02-28 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
WO2007146105A2 (en) * 2006-06-05 2007-12-21 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
CA2666789C (en) 2006-10-18 2016-11-22 Yong Zhao Embryonic-like stem cells derived from adult human peripheral blood and methods of use
WO2008085229A2 (en) * 2006-11-15 2008-07-17 Arteriocyte Inc. Cell-based therapies for treating liver disease
JP5212977B2 (en) * 2008-06-10 2013-06-19 国立大学法人福井大学 Cancer stem cell enrichment method using low oxygen culture equipment and sugar-free medium
EP2367432B1 (en) 2008-12-03 2017-08-30 Amorcyte, Inc. Infarct area perfusion-improving composition
SG10201403703XA (en) * 2009-06-29 2014-10-30 Qingfeng Chen Methods of producing humanized non-human mammals
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
EP2625264B1 (en) 2010-10-08 2022-12-07 Terumo BCT, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
WO2014113593A1 (en) * 2013-01-18 2014-07-24 Advanced Diagnostic Technologies, Llc Methods and compositions for preparing blood substitutes
US10633625B2 (en) 2013-11-16 2020-04-28 Terumo Bct, Inc. Expanding cells in a bioreactor
JP6783143B2 (en) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド Passive replenishment of medium
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3350316B1 (en) * 2015-09-15 2024-05-08 Stichting Radboud universitair medisch centrum IMPROVED METHOD FOR EX VIVO EXPANSION CD34+HSPCs INTO NK CELLS USING AN ARYL HYDROCARBON RECEPTOR ANTAGONIST
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
WO2018037091A1 (en) * 2016-08-24 2018-03-01 Hi-Stem Ggmbh Methods for the identification and isolation of hematopoietic stem and progenitor cells
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
JP7393945B2 (en) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド cell proliferation
JP7642531B2 (en) 2018-05-11 2025-03-10 ビーム セラピューティクス インク． Methods for replacing pathogenic amino acids using a programmable base editor system
CN109652369B (en) * 2019-02-28 2020-01-03 西湖生物医药科技(杭州)有限公司 Method for preparing mature red blood cells in vitro by using peripheral blood and preparation
US12043823B2 (en) 2021-03-23 2024-07-23 Terumo Bct, Inc. Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023243A (en) 1981-10-23 1991-06-11 Molecular Biosystems, Inc. Oligonucleotide therapeutic agent and method of making same
US5190931A (en) 1983-10-20 1993-03-02 The Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5168053A (en) 1989-03-24 1992-12-01 Yale University Cleavage of targeted RNA by RNAase P
US5367057A (en) 1991-04-02 1994-11-22 The Trustees Of Princeton University Tyrosine kinase receptor flk-2 and fragments thereof
US6177401B1 (en) 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
WO1994017810A1 (en) 1993-02-12 1994-08-18 The Wistar Institute Of Anatomy And Biology Recombinant cytomegalovirus vaccine
WO1994023744A1 (en) 1993-04-16 1994-10-27 The Wistar Institute Of Anatomy And Biology Recombinant cytomegalovirus vaccine

Also Published As

Publication number Publication date
CA2330208A1 (en) 1999-12-02
EP1084227A4 (en) 2002-06-12
JP2002516085A (en) 2002-06-04
US6586192B1 (en) 2003-07-01
WO1999061584A1 (en) 1999-12-02
EP1084227A1 (en) 2001-03-21

Similar Documents

Publication Publication Date Title
AU4323599A (en) Compositions and methods for use in affecting hematopoietic stem cell populations in mammals
AU4926899A (en) Hematopoietic cell composition for use in transplantation
AU4336599A (en) (in vitro) maintenance of hematopoietic stem cells
AU5420699A (en) Compositions suitable for electrochemical cells
AU3826999A (en) Compositions suitable for electrochemical cells
AU5926599A (en) Self-humidifying fuel cell
AU3388697A (en) Composition useful in elctrolytes of secondary battery cells
AU2001278877A1 (en) A composition for the delivery of live cells and methods of use
AU1268900A (en) Composite bodies used as separators in electrochemical cells
AU6929100A (en) Methods and compositions for immunotherapy of b cell involvement in promotion ofa disease condition comprising multiple sclerosis
AU2323499A (en) Cyanoacrylate compositions with terminal vinyl group in the alcohol part
AU3116800A (en) Compositions and methods for altering cell migration
AU6505299A (en) Methods for generating antigen-reactive t cells (in vitro)
AU3952399A (en) Brazing composition and seal for electrochemical cell
AU1478000A (en) (in utero) transplantation of human mesenchymal stem cells
AU9508998A (en) Methods and compositions for binding hematopoietic stem cells
AU3635695A (en) Methods for genetically modifying hematopoietic stem cells
AU2111399A (en) Wear reducing compositions and methods for their use
AU4859399A (en) Compositions and methods for treating papillomavirus-infected cells
AU9732098A (en) Hematopoietic stem cells
AU1750797A (en) Compositions and methods for mediating cell cycle progression
AU1373099A (en) Th2 cell depletion; compositions; methods
AU4030997A (en) Hematopoietic stem cell growth factor (scgf)
AU2346800A (en) Compositions and methods using cell fusion
AU2001240025A1 (en) Cell cycle proteins associated with rad9, compositions and methods of use

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase