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AU4303500A - Use of (2s)-1- ((2r,3s)-5-chloro-3- (2-chlorophenyl)- 1-(3,4-dimethoxybenzenesulfonyl)- 3-hydroxy-2,3- dihydro-1(h)- indole-2-carbonyl) pyrrolidine- 2-carboxamide in the production of medicaments used to treat raynaud's phenomenon - Google Patents

Use of (2s)-1- ((2r,3s)-5-chloro-3- (2-chlorophenyl)- 1-(3,4-dimethoxybenzenesulfonyl)- 3-hydroxy-2,3- dihydro-1(h)- indole-2-carbonyl) pyrrolidine- 2-carboxamide in the production of medicaments used to treat raynaud's phenomenon

Info

Publication number
AU4303500A
AU4303500A AU43035/00A AU4303500A AU4303500A AU 4303500 A AU4303500 A AU 4303500A AU 43035/00 A AU43035/00 A AU 43035/00A AU 4303500 A AU4303500 A AU 4303500A AU 4303500 A AU4303500 A AU 4303500A
Authority
AU
Australia
Prior art keywords
dimethoxybenzenesulfonyl
carboxamide
pyrrolidine
indole
chlorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU43035/00A
Inventor
Remi Brouard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Publication of AU4303500A publication Critical patent/AU4303500A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
AU43035/00A 1999-04-29 2000-04-25 Use of (2s)-1- ((2r,3s)-5-chloro-3- (2-chlorophenyl)- 1-(3,4-dimethoxybenzenesulfonyl)- 3-hydroxy-2,3- dihydro-1(h)- indole-2-carbonyl) pyrrolidine- 2-carboxamide in the production of medicaments used to treat raynaud's phenomenon Abandoned AU4303500A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9905434A FR2792834A1 (en) 1999-04-29 1999-04-29 USE OF SR 49059, ITS PHARMACEUTICALLY ACCEPTABLE SOLVATES AND / OR HYDATES FOR THE PREPARATION OF MEDICINES USEFUL IN THE TREATMENT OR PREVENTION OF RAYNAUD PHENOMENON
FR9905434 1999-04-29
PCT/FR2000/001085 WO2000066117A1 (en) 1999-04-29 2000-04-25 Use of (2s)-1- [(2r,3s)-5-chloro-3- (2-chlorophenyl)- 1-(3,4-dimethoxybenzenesulfonyl)- 3-hydroxy-2,3- dihydro-1h- indole-2-carbonyl] pyrrolidine- 2-carboxamide in the production of medicaments used to treat raynaud's phenomenon

Publications (1)

Publication Number Publication Date
AU4303500A true AU4303500A (en) 2000-11-17

Family

ID=9545016

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43035/00A Abandoned AU4303500A (en) 1999-04-29 2000-04-25 Use of (2s)-1- ((2r,3s)-5-chloro-3- (2-chlorophenyl)- 1-(3,4-dimethoxybenzenesulfonyl)- 3-hydroxy-2,3- dihydro-1(h)- indole-2-carbonyl) pyrrolidine- 2-carboxamide in the production of medicaments used to treat raynaud's phenomenon

Country Status (4)

Country Link
AR (1) AR023617A1 (en)
AU (1) AU4303500A (en)
FR (1) FR2792834A1 (en)
WO (1) WO2000066117A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338755A (en) * 1990-07-31 1994-08-16 Elf Sanofi N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present
FR2679903B1 (en) * 1991-08-02 1993-12-03 Elf Sanofi DERIVATIVES OF N-SULFONYL INDOLINE CARRYING AN AMIDIC FUNCTION, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME.
FR2714378B1 (en) * 1993-12-24 1996-03-15 Sanofi Sa Indol-2-one derivatives substituted in 3 with a nitrogen group, their preparation, pharmaceutical compositions containing them.
FR2775598A1 (en) * 1998-03-06 1999-09-10 Sanofi Sa PHARMACEUTICAL COMPOSITIONS COMPRISING A SELECTIVE ANTAGONIST OF ARGININE-VASOPRESSIN V1A RECEPTORS AND A SELECTIVE ANTAGONIST OF ARGININE-VASOPRESSIN V2 RECEPTORS

Also Published As

Publication number Publication date
FR2792834A1 (en) 2000-11-03
WO2000066117A1 (en) 2000-11-09
AR023617A1 (en) 2002-09-04

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase