[go: up one dir, main page]

AU4342097A - Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone - Google Patents

Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone

Info

Publication number
AU4342097A
AU4342097A AU43420/97A AU4342097A AU4342097A AU 4342097 A AU4342097 A AU 4342097A AU 43420/97 A AU43420/97 A AU 43420/97A AU 4342097 A AU4342097 A AU 4342097A AU 4342097 A AU4342097 A AU 4342097A
Authority
AU
Australia
Prior art keywords
azepines
pyrrolidines
piperidines
hexahydro
growth hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU43420/97A
Inventor
Ravi Nargund
Arthur A. Patchett
James Tata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9624172.4A external-priority patent/GB9624172D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU4342097A publication Critical patent/AU4342097A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU43420/97A 1996-09-13 1997-09-10 Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone Abandoned AU4342097A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2605496P 1996-09-13 1996-09-13
US60026054 1996-09-13
GBGB9624172.4A GB9624172D0 (en) 1996-11-19 1996-11-19 Piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
GB9624172 1996-11-19
PCT/US1997/016103 WO1998010653A1 (en) 1996-09-13 1997-09-10 Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone

Publications (1)

Publication Number Publication Date
AU4342097A true AU4342097A (en) 1998-04-02

Family

ID=26310445

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43420/97A Abandoned AU4342097A (en) 1996-09-13 1997-09-10 Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone

Country Status (2)

Country Link
AU (1) AU4342097A (en)
WO (1) WO1998010653A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998051687A1 (en) * 1997-05-14 1998-11-19 Fujisawa Pharmaceutical Co., Ltd. Piperidino derivatives which promote growth hormone release
RU2243215C2 (en) * 1998-05-11 2004-12-27 Ново Нордиск А/С Derivatives of piperidine carboxylic acids, pharmaceutical compositions containing thereof, method for stimulation of growth hormone secretion
US6294534B1 (en) 1998-06-11 2001-09-25 Merck & Co., Inc. Spiropiperidine derivatives as melanocortin receptor agonists
US6919315B1 (en) 1998-06-30 2005-07-19 Novo Nordisk A/S Compounds with growth hormone releasing properties
US6358951B1 (en) 1998-08-21 2002-03-19 Pfizer Inc. Growth hormone secretagogues
JP2002542151A (en) 1999-02-18 2002-12-10 科研製薬株式会社 Novel amide derivatives as growth hormone secretagogues
AU766191B2 (en) 1999-06-04 2003-10-09 Merck & Co., Inc. Substituted piperidines as melanocortin-4 receptor agonists
CA2379282C (en) * 1999-07-13 2010-03-09 Merck & Co., Inc. Amido spiropiperidines promote the release of growth hormone
AU4928101A (en) 2000-03-23 2001-10-03 Merck & Co Inc Spiropiperidine derivatives as melanocortin receptor agonists
EP1268449A4 (en) 2000-03-23 2004-09-15 Merck & Co Inc SUBSTITUTED PIPERIDINES AS MELANOCORTINE RECEPTOR AGONISTS
DE60140285D1 (en) 2000-05-31 2009-12-10 Pfizer Prod Inc Use of growth hormone secretagogues to promote the mobility of the digestive tract
EP1181933A3 (en) * 2000-06-29 2002-04-10 Pfizer Products Inc. Use of growth hormone secretagogues for stimulating or increasing appetite
JP2004506687A (en) 2000-08-23 2004-03-04 メルク　エンド　カムパニー　インコーポレーテッド Substituted piperidines as melanocortin receptor agonists
US6911447B2 (en) 2001-04-25 2005-06-28 The Procter & Gamble Company Melanocortin receptor ligands
CA2462200A1 (en) 2001-08-10 2003-02-20 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
US7354923B2 (en) 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7456184B2 (en) 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
CN1939529A (en) 2002-01-29 2007-04-04 Wyeth公司 Compositions and methods for modulating connexin hemichannels
US7026335B2 (en) 2002-04-30 2006-04-11 The Procter & Gamble Co. Melanocortin receptor ligands
US7132539B2 (en) 2002-10-23 2006-11-07 The Procter & Gamble Company Melanocortin receptor ligands
DE60334016D1 (en) 2002-11-05 2010-10-14 Glaxo Group Ltd ANTIBACTERIAL AGENTS
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
SG170767A1 (en) 2005-12-23 2011-05-30 Zealand Pharma As Modified lysine-mimetic compounds
CU23558A1 (en) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech COMPOUNDS ANALOG TO THE PEPTIDIC SECRETAGOGS OF THE GROWTH HORMONE
EP2074087A2 (en) 2006-12-21 2009-07-01 Wyeth Synthesis of pyrrolidine compounds
CN101657436A (en) 2007-02-09 2010-02-24 特兰齐姆制药公司 macrocyclic ghrelin receptor modulators and methods of use thereof
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2017075535A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions
WO2018202865A1 (en) 2017-05-05 2018-11-08 Zealand Pharma A/S Gap junction intercellular communication modulators and their use for the treatment of diabetic eye disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536716A (en) * 1992-12-11 1996-07-16 Merck & Co., Inc. Spiro piperidines and homologs which promote release of growth hormone
US5492920A (en) * 1993-12-10 1996-02-20 Merck & Co., Inc. Piperidine, pyrrolidine and hexahydro-1H-azepines promote release of growth hormone

Also Published As

Publication number Publication date
WO1998010653A1 (en) 1998-03-19

Similar Documents

Publication Publication Date Title
AU4342097A (en) Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
HU9601230D0 (en) Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
AU2334097A (en) 4-spiroindoline piperidines promote release of growth hormone
AU2722297A (en) Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
AU5549896A (en) 3-substituted piperidines promote release of growth hormone
AU3964795A (en) 4-heterocyclic piperidines promote release of growth hormone
AU5081298A (en) Surgical method and composition therefor
AU2591697A (en) Oil-sorbing article and methods for making and using same
AU7700598A (en) Tissue dissociating system and method
AU4850897A (en) Surgical knot and method for its formation
AU6122194A (en) Benzo-fused lactams promote release of growth hormone
AU7961694A (en) Benzo-fused lactams promote release of growth hormone
AU7401594A (en) Benzo-fused lactams promote release of growth hormone
AU3130997A (en) Dermal compositions comprising acrylate polymers, nicotine and low-swell clay
AU2741597A (en) Flowerpot and associated attachments
AU7169696A (en) 3-spirolactam, 3-spiroamino, 3-spirolactone and 3-spirobenzopyran piperidines and pyrrolidines promote release of growth hormone
AU5599898A (en) Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
GB9612276D0 (en) 4-Spiroindoline piperidines promote release of growth hormone
AU1371895A (en) Benzo-fused lactams promote release of growth hormone
ZA973301B (en) Piperidines and pyrrolidines.
AU6056500A (en) Process and composition for temporarily suppressing pain
AU7334698A (en) Process for preparing pure flupirtin maleate and its modification
AU3596900A (en) Method and composition for promoting hair growth
AU3200197A (en) New composition and methods
AU5224998A (en) Hair-curler and method for setting hair