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AU4229599A - Protease inhibitor peptides - Google Patents

Protease inhibitor peptides

Info

Publication number
AU4229599A
AU4229599A AU42295/99A AU4229599A AU4229599A AU 4229599 A AU4229599 A AU 4229599A AU 42295/99 A AU42295/99 A AU 42295/99A AU 4229599 A AU4229599 A AU 4229599A AU 4229599 A AU4229599 A AU 4229599A
Authority
AU
Australia
Prior art keywords
protease inhibitor
inhibitor peptides
peptides
protease
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42295/99A
Inventor
Deborah Damm
Brett L. Garrick
Andrew O. Lam
David D. Lesikar
Anne Bergstrom Lucas
Kathleen Mcfadden
N. Stephen Pollitt
R. Tyler White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scios LLC
Original Assignee
Scios LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scios LLC filed Critical Scios LLC
Publication of AU4229599A publication Critical patent/AU4229599A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU42295/99A 1998-06-03 1999-06-03 Protease inhibitor peptides Abandoned AU4229599A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8788598P 1998-06-03 1998-06-03
US60087885 1998-06-03
PCT/US1999/012276 WO1999063090A2 (en) 1998-06-03 1999-06-03 Protease inhibitor peptides

Publications (1)

Publication Number Publication Date
AU4229599A true AU4229599A (en) 1999-12-20

Family

ID=22207848

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42295/99A Abandoned AU4229599A (en) 1998-06-03 1999-06-03 Protease inhibitor peptides

Country Status (5)

Country Link
EP (1) EP1082431A2 (en)
JP (1) JP2002517197A (en)
AU (1) AU4229599A (en)
CA (1) CA2330191A1 (en)
WO (1) WO1999063090A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
ES2348230T3 (en) * 2002-06-07 2010-12-01 Dyax Corp. PREVENTION AND REDUCTION OF THE ISCHEMIA.
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
PT2386310T (en) 2002-08-28 2019-02-05 Dyax Corp METHODS FOR PRESERVING ORGANS AND TISSUES
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US8637454B2 (en) 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
RS62853B1 (en) 2010-01-06 2022-02-28 Takeda Pharmaceuticals Co Plasma kallikrein binding proteins
CN103635489B (en) 2011-01-06 2016-04-13 戴埃克斯有限公司 plasma kallikrein binding protein
US20180362616A1 (en) * 2015-12-10 2018-12-20 The National Institute for Biotechnology in the Negev Ltd. VARIANTS OF AMYLOID beta-PROTEIN PRECURSOR INHIBITOR DOMAIN
CN108602893A (en) 2015-12-11 2018-09-28 戴埃克斯有限公司 Plasma kallikrein inhibitors and their use in the treatment of episodes of hereditary angioedema
CN110051830A (en) * 2019-03-14 2019-07-26 苏州新凝生物医药科技有限公司 A kind of protease nexin II KPI protein mutant application
JP2023510854A (en) 2020-01-13 2023-03-15 武田薬品工業株式会社 Plasma kallikrein inhibitors and their use for treating pediatric hereditary angioedema attacks

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5663143A (en) * 1988-09-02 1997-09-02 Dyax Corp. Engineered human-derived kunitz domains that inhibit human neutrophil elastase
WO1993009233A2 (en) * 1991-10-31 1993-05-13 The Salk Institute Biotechnology/Industrial Associates Inc. Recombinant amyloid precursor protein inhibitor domain and treatment of various disease states
EP0827539A2 (en) * 1995-05-08 1998-03-11 Scios Inc. Kunitz type protease inhibitors

Also Published As

Publication number Publication date
WO1999063090A3 (en) 2000-03-02
WO1999063090A2 (en) 1999-12-09
EP1082431A2 (en) 2001-03-14
CA2330191A1 (en) 1999-12-09
JP2002517197A (en) 2002-06-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase