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AU4228997A - Method for treating homozygous familial hypercholesterolemia - Google Patents

Method for treating homozygous familial hypercholesterolemia

Info

Publication number
AU4228997A
AU4228997A AU42289/97A AU4228997A AU4228997A AU 4228997 A AU4228997 A AU 4228997A AU 42289/97 A AU42289/97 A AU 42289/97A AU 4228997 A AU4228997 A AU 4228997A AU 4228997 A AU4228997 A AU 4228997A
Authority
AU
Australia
Prior art keywords
familial hypercholesterolemia
homozygous familial
treating
treating homozygous
hypercholesterolemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42289/97A
Inventor
Yale B Mitchel
Jonathan A. Tobert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9617898.3A external-priority patent/GB9617898D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU4228997A publication Critical patent/AU4228997A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU42289/97A 1996-07-09 1997-07-03 Method for treating homozygous familial hypercholesterolemia Abandoned AU4228997A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US2142096P 1996-07-09 1996-07-09
US60021420 1996-07-09
GBGB9617898.3A GB9617898D0 (en) 1996-08-28 1996-08-28 Method for treating homozygous familial hypercholesterolemia
GB9617898 1996-08-28
US2935196P 1996-10-31 1996-10-31
US60029351 1996-10-31
PCT/US1997/011792 WO1998001100A2 (en) 1996-07-09 1997-07-03 Method for treating homozygous familial hypercholesterolemia

Publications (1)

Publication Number Publication Date
AU4228997A true AU4228997A (en) 1998-02-02

Family

ID=27268450

Family Applications (3)

Application Number Title Priority Date Filing Date
AU42289/97A Abandoned AU4228997A (en) 1996-07-09 1997-07-03 Method for treating homozygous familial hypercholesterolemia
AU36672/97A Abandoned AU3667297A (en) 1996-07-09 1997-07-03 Therapy for combined hyperlipidemia
AU43261/97A Abandoned AU4326197A (en) 1996-07-09 1997-07-03 Pharmaceutical compositions

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU36672/97A Abandoned AU3667297A (en) 1996-07-09 1997-07-03 Therapy for combined hyperlipidemia
AU43261/97A Abandoned AU4326197A (en) 1996-07-09 1997-07-03 Pharmaceutical compositions

Country Status (2)

Country Link
AU (3) AU4228997A (en)
WO (3) WO1998001116A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030212996A1 (en) * 1996-02-08 2003-11-13 Wolzien Thomas R. System for interconnection of audio program data transmitted by radio to remote vehicle or individual with GPS location
SI1117392T1 (en) * 1998-09-30 2004-06-30 Warner-Lambert Company Llc Method for preventing or delaying catheter-based revascularization
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
IL156445A0 (en) 2001-01-26 2004-01-04 Schering Corp Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
ME00145B (en) 2001-01-26 2010-10-10 Merck Sharp & Dohme The use of substituted azetidinone compounds for the treatment of sitosterolemia
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
WO2002079174A2 (en) 2001-03-28 2002-10-10 Schering Corporation Enantioselective synthesis of azetidinone intermediate compounds
ES2272776T3 (en) 2001-09-21 2007-05-01 Schering Corporation TREATMENT OF XANTOMAS WITH DERIVATIVES OF AZETIDINONE AS INHIBITORS OF STEROL ABSORPTION.
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
CN1620499A (en) * 2001-12-21 2005-05-25 哥本哈根大学医院 Gamete recruitment and developmental competence in mammals - by inhibiting de novo sterol biosynthesis and/or promoting sterol efflux
AR040588A1 (en) 2002-07-26 2005-04-13 Schering Corp PHARMACEUTICAL FORMULATION INCLUDING AN INHIBITOR OF CHOLESTEROL ABSORPTION AND AN INHIBITOR OF A HMGCO TO REDUCTASE
WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
DE602004018617D1 (en) 2003-03-07 2009-02-05 Schering Corp SUBSTITUTED AZETIDINONE DERIVATIVES, THEIR PHARMACEUTICAL FORMULATIONS AND THEIR USE FOR THE TREATMENT OF HYPERCHOLESTEROLMIA
DE602004016123D1 (en) 2003-03-07 2008-10-09 Schering Corp SUBSTITUTED AZETIDINONE DERIVATIVES, THEIR PHARMACEUTICAL FORMULATIONS AND THEIR USE FOR THE TREATMENT OF HYPERCHOLESTEROLMIA
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US7192944B2 (en) 2003-03-07 2007-03-20 Schering Corp. Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JOP20080381B1 (en) 2007-08-23 2023-03-28 Amgen Inc Antigen Binding Proteins to Proprotein Convertase subtillisin Kexin type 9 (pcsk9)
JOP20200043A1 (en) 2011-05-10 2017-06-16 Amgen Inc Ways to treat or prevent cholesterol disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806564A (en) * 1987-05-26 1989-02-21 Merck & Co., Inc. Antihypercholesterolemic beta-lactones
US4997849A (en) * 1989-06-23 1991-03-05 Merck & Co., Inc. Microbial transformation of simvastatin
US5393893A (en) * 1993-11-08 1995-02-28 Apotex, Inc. Process for producing simvastatin and analogs thereof

Also Published As

Publication number Publication date
WO1998001100A3 (en) 1998-02-12
WO1998001119A2 (en) 1998-01-15
AU4326197A (en) 1998-02-02
WO1998001100A2 (en) 1998-01-15
WO1998001116A1 (en) 1998-01-15
AU3667297A (en) 1998-02-02

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