AU4198400A - Neurotrophic thio substituted pyrimidines - Google Patents

Neurotrophic thio substituted pyrimidines

Info

Publication number: AU4198400A
Authority: AU; Australia
Prior art keywords: neurotrophic; substituted pyrimidines; thio substituted; thio; pyrimidines
Prior art date: 1999-04-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU41984/00A

Other languages

English (en)

Inventor

Lilia M. Beauchamp

James L. Kelley

Thomas A. Krenitsky

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Krenitsky Pharmaceuticals Inc

Original Assignee

Krenitsky Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-06

Filing date

2000-04-05

Publication date

2000-10-23

2000-04-05 Application filed by Krenitsky Pharmaceuticals Inc filed Critical Krenitsky Pharmaceuticals Inc

2000-10-23 Publication of AU4198400A publication Critical patent/AU4198400A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AU41984/00A 1999-04-06 2000-04-05 Neurotrophic thio substituted pyrimidines Abandoned AU4198400A (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US12792399P	1999-04-06	1999-04-06
US60127923		1999-04-06
US12884299P	1999-04-12	1999-04-12
US60128842		1999-04-12
PCT/US2000/009004 WO2000059893A1 (fr)	1999-04-06	2000-04-05	Thiopyrimidines neurotrophiques substitues

Publications (1)

Publication Number	Publication Date
AU4198400A true AU4198400A (en)	2000-10-23

Family

ID=26826090

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU41984/00A Abandoned AU4198400A (en)	1999-04-06	2000-04-05	Neurotrophic thio substituted pyrimidines

Country Status (4)

Country	Link
EP (1)	EP1165522A1 (fr)
AU (1)	AU4198400A (fr)
CA (1)	CA2369945A1 (fr)
WO (1)	WO2000059893A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1217000A1 (fr) *	2000-12-23	2002-06-26	Aventis Pharma Deutschland GmbH	Inhibiteurs du factor Xa et factor VIIa
TWI329105B (en)	2002-02-01	2010-08-21	Rigel Pharmaceuticals Inc	2,4-pyrimidinediamine compounds and their uses
JP2006514989A (ja)	2002-07-29	2006-05-18	ライジェルファーマシューティカルズ	２，４−ピリミジンジアミン化合物による自己免疫疾患の治療および予防方法
US6800652B2 (en)	2002-08-16	2004-10-05	Pfizer Inc.	Diaryl compounds
AU2004265288A1 (en)	2003-07-30	2005-02-24	Rigel Pharmaceuticals, Inc.	2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
EP1814878B1 (fr)	2004-11-24	2012-01-04	Rigel Pharmaceuticals, Inc.	Composes de spiro-2, 4-pyrimidinediamine et leurs utilisations
FR2932482B1 (fr)	2008-06-13	2010-10-08	Sanofi Aventis	Nouveaux derives de (phenyl-3,6-dihydro-2h-pyridinyl)- (piperazinyl ponte)-1-alcanone et leur utilisation comme inhibiteurs de p75
FR2932481B1 (fr)	2008-06-13	2010-10-08	Sanofi Aventis	Derives de 4-{2-°4-phenyl-3,6-dihydro-2h-pyridin-1-yl!-2- oxo-alkyl}-1-piperazin-2-one, leur preparation et leur application en therapeutique.
CA2771190C (fr)	2009-08-17	2020-01-21	Memorial Sloan-Kettering Cancer Center	Composes de liaison a une proteine de choc thermique, compositions et procedes pour les fabriquer et les utiliser
FR2953839A1 (fr)	2009-12-14	2011-06-17	Sanofi Aventis	Nouveaux derives d'(heterocycle-piperidine condensee)-(piperazinyl)-1alcanone ou d'(heterocycle-pyrrolidine condensee)-(piperazinyl)-1alcanone et leur utilisation comme inhibiteurs de p75
FR2953836B1 (fr)	2009-12-14	2012-03-16	Sanofi Aventis	Nouveaux derives (heterocycle-tetrahydro-pyridine)-(piperazinyl)-1-alcanone et (heterocycle-dihydro-pyrrolidine)-(piperazinyl)-1-alcanone et leur utilisation comme inhibiteurs de p75
EP2606894A1 (fr)	2011-12-20	2013-06-26	Sanofi	Nouvelle utilisation thérapeutique des antagonistes du récepteur p75
JO3517B1 (ar)	2014-01-17	2020-07-05	Novartis Ag	ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
EP3094627B1 (fr)	2014-01-17	2018-08-22	Novartis AG	Dérivés de 1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine et compositions les contenant pour l'inhibition de l'activité de shp2
CN105899493B (zh)	2014-01-17	2019-03-29	诺华股份有限公司	用于抑制shp2活性的1-(三嗪-3-基/哒嗪-3-基)-哌(-嗪)啶衍生物及其组合物
WO2016203404A1 (fr)	2015-06-19	2016-12-22	Novartis Ag	Composés et compositions pour inhiber l'activité de shp2
US10287266B2 (en)	2015-06-19	2019-05-14	Novartis Ag	Compounds and compositions for inhibiting the activity of SHP2
WO2016203405A1 (fr)	2015-06-19	2016-12-22	Novartis Ag	Composés et compositions pour inhiber l'activité de shp2
KR20180122406A (ko) *	2016-03-14	2018-11-12	애퍼런트 파마슈티컬스 인크.	피리미딘 및 그의 변이체, 및 그의 용도
WO2017165255A1 (fr) *	2016-03-25	2017-09-28	Afferent Pharmaceuticals Inc.	Pyrimidines et variants de celles-ci, et leurs utilisations
KR102457146B1 (ko)	2016-06-14	2022-10-19	노파르티스 아게	Shp2의 활성을 억제하기 위한 화합물 및 조성물
CA3048340A1 (fr)	2017-01-10	2018-07-19	Novartis Ag	Combinaison pharmaceutique comprenant un inhibiteur d'alk et un inhibiteur de shp2
CN117024405A (zh) *	2022-05-09	2023-11-10	浙江同源康医药股份有限公司	多环类化合物及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB951432A (en) *	1959-03-17	1964-03-04	Wellcome Found	Pyrimidine derivatives and the manufacture thereof
WO1996031488A1 (fr) *	1995-04-03	1996-10-10	Sumitomo Pharmaceuticals Company, Limited	Nouveaux derives de pyrimidine efficaces en tant que medicament psychotrope et leur procede de fabrication

2000
- 2000-04-05 AU AU41984/00A patent/AU4198400A/en not_active Abandoned
- 2000-04-05 WO PCT/US2000/009004 patent/WO2000059893A1/fr not_active Ceased
- 2000-04-05 EP EP00921705A patent/EP1165522A1/fr not_active Withdrawn
- 2000-04-05 CA CA002369945A patent/CA2369945A1/fr not_active Abandoned

Also Published As

Publication number	Publication date
WO2000059893A1 (fr)	2000-10-12
CA2369945A1 (fr)	2000-10-12
EP1165522A1 (fr)	2002-01-02

Publication	Publication Date	Title
AU4198400A (en)	2000-10-23	Neurotrophic thio substituted pyrimidines
AU5759999A (en)	2000-04-17	Pyrimidone derivatives
AU3420599A (en)	1999-11-08	Novel 2-heterocyclically substituted dihydropyrimidines
AU3813399A (en)	1999-11-08	Dihydropyrimidines
AU2634600A (en)	2000-08-18	Pipetter
AU5325400A (en)	2001-01-02	Multi-connection via
AU1173201A (en)	2001-05-14	Skin-gripper
PL351690A1 (en)	2003-06-02	Pyrimidinone compounds
AU4556700A (en)	2000-11-17	Pyrimidine compounds
AU7419300A (en)	2001-04-30	Quinazolinones
AU5391099A (en)	2000-02-21	Substituted quinazoline derivatives
AU1104301A (en)	2001-05-08	Primary n-hydroxylamines
AU2187301A (en)	2001-06-25	Protein kinase regulation
AU2002362806A1 (en)	2003-07-03	Pyrimidine derivatives
AU3819200A (en)	2000-11-02	2,4-diamino-pyrimidine derivatives
AU7654800A (en)	2001-04-30	Quinazolinones
AU5858000A (en)	2001-01-02	Switched capacitors
AU5039699A (en)	2001-01-22	Lamp structure
AU3467197A (en)	1998-10-22	Tetracyclical derivatives from pyrimidine
AU1800700A (en)	2000-07-31	Ikk3 kinase
AU1042701A (en)	2001-05-08	Antiviral combinations
AU1675800A (en)	2000-07-24	Lighting system
AU6827300A (en)	2001-03-05	Substituted arylalkylamino-1,3,5-triazines
AU6567400A (en)	2001-03-05	Substituted 2-imino-thiazolines
AU1785599A (en)	1999-08-02	Novel pyrimidine derivatives

Legal Events

Date	Code	Title	Description
2002-03-07	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase