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AU3835285A - Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation - Google Patents

Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation

Info

Publication number
AU3835285A
AU3835285A AU38352/85A AU3835285A AU3835285A AU 3835285 A AU3835285 A AU 3835285A AU 38352/85 A AU38352/85 A AU 38352/85A AU 3835285 A AU3835285 A AU 3835285A AU 3835285 A AU3835285 A AU 3835285A
Authority
AU
Australia
Prior art keywords
instable
water
pharmaceutical compositions
sparingly soluble
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU38352/85A
Other versions
AU565966B2 (en
Inventor
Ulrich Brauns
Bernhard Willi Werner Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6217510&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU3835285(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of AU3835285A publication Critical patent/AU3835285A/en
Application granted granted Critical
Publication of AU565966B2 publication Critical patent/AU565966B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel pharmaceutical compositions comprise inclusion compounds of drugs, which are instable or only sparingly soluble in water, with partially etherified beta -cyclodextrin derivatives having hydroxyalkyl and optionally additional alkyl groups.
AU38352/85A 1983-12-21 1984-12-20 Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation Expired AU565966B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833346123 DE3346123A1 (en) 1983-12-21 1983-12-21 PHARMACEUTICAL PREPARATIONS OF SUBSTANCES MEDICAL OR UNSTABLE IN WATER AND METHOD FOR THE PRODUCTION THEREOF
DE3346123 1983-12-21

Publications (2)

Publication Number Publication Date
AU3835285A true AU3835285A (en) 1985-07-12
AU565966B2 AU565966B2 (en) 1987-10-01

Family

ID=6217510

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38352/85A Expired AU565966B2 (en) 1983-12-21 1984-12-20 Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation

Country Status (17)

Country Link
EP (1) EP0149197B2 (en)
JP (1) JPS61500788A (en)
AT (1) ATE51145T1 (en)
AU (1) AU565966B2 (en)
CA (1) CA1222697A (en)
CY (1) CY1689A (en)
DE (2) DE3346123A1 (en)
DK (1) DK175288B1 (en)
FI (1) FI86140C (en)
HK (1) HK131293A (en)
HU (1) HU200943B (en)
LU (1) LU90283I2 (en)
NL (1) NL980009I1 (en)
NO (1) NO2000007I1 (en)
SG (1) SG24893G (en)
WO (1) WO1985002767A1 (en)
ZA (1) ZA8410042B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002141A1 (en) * 1988-08-31 1990-03-08 Australian Commercial Research & Development Limited Compositions and methods for drug delivery and chromatography
AU603895B2 (en) * 1987-05-18 1990-11-29 Janssen Pharmaceutica N.V. Improved flunarizine-containing compositions
WO1991004026A1 (en) * 1989-09-14 1991-04-04 Australian Commercial Research & Development Limited Drug delivery compositions
WO1991013100A1 (en) * 1990-03-02 1991-09-05 Australian Commercial Research & Development Limited Cyclodextrin compositions and methods for pharmaceutical and industrial applications
AU618995B2 (en) * 1987-12-30 1992-01-16 University Of Florida Pharmaceutical formulations for parenteral use

Families Citing this family (130)

* Cited by examiner, † Cited by third party
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JP2577049B2 (en) * 1987-06-04 1997-01-29 三共株式会社 Cyclosporine preparation
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US4877774A (en) * 1987-09-09 1989-10-31 The United States Of America As Represented By The Department Of Health And Human Services Administration of steroid hormones
US5256652A (en) * 1987-11-12 1993-10-26 Pharmedic Co. Topical compositions and methods for treatment of male impotence
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US5017566A (en) * 1987-12-30 1991-05-21 University Of Florida Redox systems for brain-targeted drug delivery
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US5658894A (en) * 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
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US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids

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AU603895B2 (en) * 1987-05-18 1990-11-29 Janssen Pharmaceutica N.V. Improved flunarizine-containing compositions
AU618995B2 (en) * 1987-12-30 1992-01-16 University Of Florida Pharmaceutical formulations for parenteral use
WO1990002141A1 (en) * 1988-08-31 1990-03-08 Australian Commercial Research & Development Limited Compositions and methods for drug delivery and chromatography
WO1991004026A1 (en) * 1989-09-14 1991-04-04 Australian Commercial Research & Development Limited Drug delivery compositions
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CA1222697A (en) 1987-06-09
FI853198A0 (en) 1985-08-20
DK175288B1 (en) 2004-08-09
EP0149197A2 (en) 1985-07-24
JPH0570612B2 (en) 1993-10-05
EP0149197B2 (en) 1997-01-08
AU565966B2 (en) 1987-10-01
HK131293A (en) 1993-12-03
FI86140C (en) 1992-07-27
HUT40561A (en) 1987-01-28
DK359585D0 (en) 1985-08-07
EP0149197A3 (en) 1985-08-14
FI86140B (en) 1992-04-15
ATE51145T1 (en) 1990-04-15
HU200943B (en) 1990-09-28
NL980009I1 (en) 1998-05-06
SG24893G (en) 1993-08-06
LU90283I2 (en) 1998-11-03
DK359585A (en) 1985-08-07
FI853198L (en) 1985-08-20
EP0149197B1 (en) 1990-03-21
ZA8410042B (en) 1985-09-25
DE3481680D1 (en) 1990-04-26
WO1985002767A1 (en) 1985-07-04

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