AU3818278A - l-(INDOL-4-YLOXY)-3-AMINO-2-PROPANOI COMPOUNDS - Google Patents

l-(INDOL-4-YLOXY)-3-AMINO-2-PROPANOI COMPOUNDS

Info

Publication number: AU3818278A
Authority: AU; Australia
Prior art keywords: propanoi; indol; yloxy; amino; compounds
Prior art date: 1977-07-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU38182/78A

Other versions

AU523105B2 (en

Inventor

Berthold Richard

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-07-21

Filing date

1978-07-19

Publication date

1980-01-24

1977-07-21 Priority claimed from CH907777A external-priority patent/CH632246A5/en

1978-07-19 Application filed by Sandoz AG filed Critical Sandoz AG

1980-01-24 Publication of AU3818278A publication Critical patent/AU3818278A/en

1982-07-15 Application granted granted Critical

1982-07-15 Publication of AU523105B2 publication Critical patent/AU523105B2/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AU38182/78A 1977-07-21 1978-07-19 l-(INDOL-4-YLOXY)-3-AMINO-2-PROPANOI COMPOUNDS Expired AU523105B2 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
CH906577		1977-07-21
CH907777A CH632246A5 (en)	1977-07-21	1977-07-21	Process for preparing novel 3-aminopropoxyindoles
CH907377		1977-07-21
CH907077		1977-07-21
CHCH9065/77		1977-07-21

Publications (2)

Publication Number	Publication Date
AU3818278A true AU3818278A (en)	1980-01-24
AU523105B2 AU523105B2 (en)	1982-07-15

Family

ID=27429188

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU38182/78A Expired AU523105B2 (en)	1977-07-21	1978-07-19	l-(INDOL-4-YLOXY)-3-AMINO-2-PROPANOI COMPOUNDS

Country Status (18)

Country	Link
JP (1)	JPS5422364A (en)
AU (1)	AU523105B2 (en)
BE (1)	BE869133A (en)
CA (1)	CA1098909A (en)
DE (1)	DE2830211A1 (en)
DK (1)	DK312878A (en)
ES (1)	ES471863A1 (en)
FI (1)	FI782229A7 (en)
FR (1)	FR2398058A1 (en)
GB (1)	GB2001971B (en)
IE (1)	IE47131B1 (en)
IL (1)	IL55170A (en)
IT (1)	IT1105092B (en)
NL (1)	NL7807626A (en)
NZ (1)	NZ187909A (en)
PT (1)	PT68317A (en)
SE (1)	SE435374B (en)
SU (1)	SU843740A3 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2905877A1 (en) *	1979-02-16	1980-08-28	Boehringer Mannheim Gmbh	NEW AMINOPROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3068678D1 (en) *	1979-08-10	1984-08-30	Sandoz Ag	3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
DE3029980A1 (en) *	1980-08-08	1982-03-11	Boehringer Mannheim Gmbh, 6800 Mannheim	INDOLDER DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE3030047A1 (en) *	1980-08-08	1982-03-11	Boehringer Mannheim Gmbh, 6800 Mannheim	NEW AMINOPROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3131146A1 (en) *	1981-08-06	1983-02-24	Boehringer Mannheim Gmbh, 6800 Mannheim	NEW HETEROARYLOXYPROPANOLAMINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
ZA967892B (en) *	1995-09-21	1998-03-18	Lilly Co Eli	Selective β3 adrenergic agonists.
NZ332068A (en)	1996-04-09	2001-03-30	Smithkline Beecham	Alpha, alpha-disubstituted arylalkylamine derivatives as calcilytic compounds
US6818660B2 (en)	1996-04-09	2004-11-16	Nps Pharmaceuticals, Inc.	Calcilytic compounds
ES2171839T3 (en) *	1996-09-05	2002-09-16	Lilly Co Eli	CARBAZOL ANALOGS AS BETA3 SELECTIVE ADRENERGIC AGONISTS.
TW483881B (en)	1996-12-03	2002-04-21	Nps Pharma Inc	Calcilytic compounds
US7202261B2 (en)	1996-12-03	2007-04-10	Nps Pharmaceuticals, Inc.	Calcilytic compounds
WO2001036412A1 (en) *	1999-11-15	2001-05-25	Eli Lilly And Company	Process for the preparation of aryloxy propanolamines
AU2017263657A1 (en)	2016-05-13	2018-11-29	The Board Of Trustees Of The Leland Stanford Junior University	Adrenergic receptor modulating compounds and methods of using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1547056A (en) *	1966-12-13	1968-11-22	Sandoz Sa	Indole derivatives and their preparation
FR2019185A1 (en) *	1968-09-30	1970-06-26	Sandoz Sa	4-(2-hydroxy-3-amino-propoxy)-indole-2-carboxy- - lic acids and esters and 2-hydroxymethylindoles as beta
US3699123A (en) *	1970-03-24	1972-10-17	Sandoz Ltd	4-(3-amino-2-hydroxy-propoxy) indole derivatives
US4076829A (en) *	1974-11-16	1978-02-28	Boehringer Mannheim Gmbh	Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
DE2508251C2 (en) *	1975-02-26	1983-12-29	Boehringer Mannheim Gmbh, 6800 Mannheim	Derivatives of indole, processes for their preparation and medicaments containing them
DE2633839A1 (en) *	1975-08-07	1977-02-24	Sandoz Ag	NEW 4-AMINOPROPOXYINDOLDE DERIVATIVES, THEIR PRODUCTION AND USE
DE2635209C2 (en) *	1975-08-15	1983-01-27	Sandoz-Patent-GmbH, 7850 Lörrach	4- (2-Benzoyloxy-3-tert-butylamino-propoxy) -2-methylindole, its (S) -enantiomer, their acid addition salts, processes for their preparation and medicaments containing these compounds

1978
- 1978-07-10 DE DE19782830211 patent/DE2830211A1/en not_active Ceased
- 1978-07-12 SE SE7807753A patent/SE435374B/en unknown
- 1978-07-12 FI FI782229A patent/FI782229A7/en not_active Application Discontinuation
- 1978-07-12 DK DK312878A patent/DK312878A/en not_active Application Discontinuation
- 1978-07-14 IT IT50299/78A patent/IT1105092B/en active
- 1978-07-17 NL NL7807626A patent/NL7807626A/en not_active Application Discontinuation
- 1978-07-19 IL IL55170A patent/IL55170A/en unknown
- 1978-07-19 IE IE1448/78A patent/IE47131B1/en unknown
- 1978-07-19 ES ES471863A patent/ES471863A1/en not_active Expired
- 1978-07-19 SU SU782639449A patent/SU843740A3/en active
- 1978-07-19 GB GB7830345A patent/GB2001971B/en not_active Expired
- 1978-07-19 NZ NZ187909A patent/NZ187909A/en unknown
- 1978-07-19 BE BE189392A patent/BE869133A/en not_active IP Right Cessation
- 1978-07-19 PT PT68317A patent/PT68317A/en unknown
- 1978-07-19 AU AU38182/78A patent/AU523105B2/en not_active Expired
- 1978-07-20 JP JP8781878A patent/JPS5422364A/en active Pending
- 1978-07-20 CA CA307,768A patent/CA1098909A/en not_active Expired
- 1978-07-21 FR FR7821679A patent/FR2398058A1/en active Granted

Also Published As

Publication number	Publication date
IE47131B1 (en)	1983-12-28
DE2830211A1 (en)	1979-02-01
FR2398058B1 (en)	1982-08-06
SE435374B (en)	1984-09-24
JPS5422364A (en)	1979-02-20
PT68317A (en)	1978-08-01
GB2001971A (en)	1979-02-14
NZ187909A (en)	1981-04-24
DK312878A (en)	1979-01-22
FI782229A7 (en)	1979-01-22
ES471863A1 (en)	1979-10-01
IT7850299A0 (en)	1978-07-14
FR2398058A1 (en)	1979-02-16
IE781448L (en)	1979-01-21
BE869133A (en)	1979-01-19
AU523105B2 (en)	1982-07-15
IT1105092B (en)	1985-10-28
GB2001971B (en)	1982-02-10
CA1098909A (en)	1981-04-07
SU843740A3 (en)	1981-06-30
SE7807753L (en)	1979-01-22
NL7807626A (en)	1979-01-23
IL55170A (en)	1982-07-30
IL55170A0 (en)	1978-09-29

Publication	Publication Date	Title
AU527917B2 (en)	1983-03-31	2-pemer compounds
AU3409978A (en)	1979-09-20	4-acylaminophenyl-ethanolamines
AU511062B2 (en)	1980-07-24	Oxazolinoazetoine compounds
AU3069177A (en)	1979-06-21	Inkduct
AU523105B2 (en)	1982-07-15	l-(INDOL-4-YLOXY)-3-AMINO-2-PROPANOI COMPOUNDS
AU514377B2 (en)	1981-02-05	l-OXADETHIACEPHAM COMPOUNDS
AU3347978A (en)	1979-08-30	Phenyl-benzimidazoyl-furanes
AU3216278A (en)	1979-07-12	Phenylcarbamoyl-pyrazolines
AU3216478A (en)	1979-07-12	Phenylcarbamoyl-2-pyrazolines
AU521453B2 (en)	1982-04-01	Silicon-oxime compounds
AU3239278A (en)	1979-07-19	Dithienylalkylamines
AU3307178A (en)	1979-08-16	Chloroacetanylides
AU3401278A (en)	1979-09-13	Sipper-seal
AU3492478A (en)	1979-10-18	4-alkylthio-2-trifluoromethylalkanesulfonides
AU515770B2 (en)	1981-04-30	Substituted 2-cyclopropylchromones
AU521538B2 (en)	1982-04-08	Heterovaccine containing lactobacterium
AU3418778A (en)	1979-09-20	Hydroxylated-1d-2d-methylene-steroids
AU515062B2 (en)	1981-03-12	Phosphonomethylglycerine compounds
AU3246878A (en)	1979-07-26	Arylenedioxy-bis-diketones
AU3397178A (en)	1979-09-13	N-hydroxy-n-phosphonomethylglycines
AU519274B2 (en)	1981-11-19	Substituted carbamoyloxyphenyl)-dialkylsulphonium compounds
AU3234978A (en)	1979-07-19	Carbimidocarbonylphenylformamidines
AU3360278A (en)	1979-08-30	Triazolo-thieno-diazepin-1-ones
AU521851B2 (en)	1982-05-06	Spirodenzofuranone compounds
AU520056B2 (en)	1982-01-14	Phenylazophenyloxytrizxolyl compounds