AU3843189A - 5-deaza-5,7-disubstituted-aminopterin analogues - Google Patents
5-deaza-5,7-disubstituted-aminopterin analoguesInfo
- Publication number
- AU3843189A AU3843189A AU38431/89A AU3843189A AU3843189A AU 3843189 A AU3843189 A AU 3843189A AU 38431/89 A AU38431/89 A AU 38431/89A AU 3843189 A AU3843189 A AU 3843189A AU 3843189 A AU3843189 A AU 3843189A
- Authority
- AU
- Australia
- Prior art keywords
- deaza
- aminopterin
- disubstituted
- analogues
- aminopterin analogues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21451088A | 1988-07-01 | 1988-07-01 | |
| US214510 | 1988-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU3843189A true AU3843189A (en) | 1990-01-23 |
Family
ID=22799353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU38431/89A Abandoned AU3843189A (en) | 1988-07-01 | 1989-06-22 | 5-deaza-5,7-disubstituted-aminopterin analogues |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0377031A1 (en) |
| JP (1) | JPH03500176A (en) |
| AU (1) | AU3843189A (en) |
| WO (1) | WO1990000172A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU631055B2 (en) * | 1990-04-12 | 1992-11-12 | Health Research Inc. | Difluoroglutamic acid conjugates with folates and anti- folates for the treatment of neoplastic diseases |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993022312A1 (en) * | 1992-04-29 | 1993-11-11 | Sri International | Deazaaminopterins for treatment of inflammation |
| WO2010016846A1 (en) * | 2008-08-08 | 2010-02-11 | Kalypsys, Inc. | Heterocyclic modulators of tgr5 for treatment of disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4061642A (en) * | 1972-06-22 | 1977-12-06 | Cassella Farbwerke Mainkur Ag | 2,4,6-Trisubstituted-3-pyridine carboxamides |
| US4431805A (en) * | 1981-09-25 | 1984-02-14 | Southern Research Institute | Pyrido[2,3-d]-pyrimidines |
| US4628089A (en) * | 1982-01-11 | 1986-12-09 | Southern Research Institute | Pyrido(2,3-D)pyrimidines |
-
1989
- 1989-06-22 JP JP1507160A patent/JPH03500176A/en active Pending
- 1989-06-22 AU AU38431/89A patent/AU3843189A/en not_active Abandoned
- 1989-06-22 WO PCT/US1989/002725 patent/WO1990000172A1/en not_active Ceased
- 1989-06-22 EP EP19890907612 patent/EP0377031A1/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU631055B2 (en) * | 1990-04-12 | 1992-11-12 | Health Research Inc. | Difluoroglutamic acid conjugates with folates and anti- folates for the treatment of neoplastic diseases |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0377031A1 (en) | 1990-07-11 |
| WO1990000172A1 (en) | 1990-01-11 |
| JPH03500176A (en) | 1991-01-17 |
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