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AU3774389A - 4'-deoxy-2'-halo-anthracycline antibiotics, methods for their use, and intermediates and methods for synthesis thereof - Google Patents

4'-deoxy-2'-halo-anthracycline antibiotics, methods for their use, and intermediates and methods for synthesis thereof

Info

Publication number
AU3774389A
AU3774389A AU37743/89A AU3774389A AU3774389A AU 3774389 A AU3774389 A AU 3774389A AU 37743/89 A AU37743/89 A AU 37743/89A AU 3774389 A AU3774389 A AU 3774389A AU 3774389 A AU3774389 A AU 3774389A
Authority
AU
Australia
Prior art keywords
methods
deoxy
intermediates
halo
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU37743/89A
Inventor
Nouri Meamati-M
Roman Perez-Soler
Waldemar Priebe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System, University of Texas at Austin filed Critical University of Texas System
Publication of AU3774389A publication Critical patent/AU3774389A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU37743/89A 1988-06-27 1989-06-09 4'-deoxy-2'-halo-anthracycline antibiotics, methods for their use, and intermediates and methods for synthesis thereof Abandoned AU3774389A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21233588A 1988-06-27 1988-06-27
US212335 1988-06-27

Publications (1)

Publication Number Publication Date
AU3774389A true AU3774389A (en) 1990-01-23

Family

ID=22790571

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37743/89A Abandoned AU3774389A (en) 1988-06-27 1989-06-09 4'-deoxy-2'-halo-anthracycline antibiotics, methods for their use, and intermediates and methods for synthesis thereof

Country Status (2)

Country Link
AU (1) AU3774389A (en)
WO (1) WO1990000173A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615774B2 (en) * 1988-10-11 1991-10-10 Sicor Societa' Italiana Corticosteroidi S.P.A. Improved process for the conversion of daunorubicin into doxorubicin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79729B (en) * 1982-12-20 1984-10-31 Univ Ohio State Res Found
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615774B2 (en) * 1988-10-11 1991-10-10 Sicor Societa' Italiana Corticosteroidi S.P.A. Improved process for the conversion of daunorubicin into doxorubicin

Also Published As

Publication number Publication date
WO1990000173A1 (en) 1990-01-11

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