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AU3661300A - Novel method for the production of etoposide - Google Patents

Novel method for the production of etoposide

Info

Publication number
AU3661300A
AU3661300A AU36613/00A AU3661300A AU3661300A AU 3661300 A AU3661300 A AU 3661300A AU 36613/00 A AU36613/00 A AU 36613/00A AU 3661300 A AU3661300 A AU 3661300A AU 3661300 A AU3661300 A AU 3661300A
Authority
AU
Australia
Prior art keywords
etoposide
production
novel method
diphenoxyacetyl
demethylepipodophyllotoxine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU36613/00A
Inventor
Jean Fabre
Yves Guminski
Thierry Imbert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of AU3661300A publication Critical patent/AU3661300A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a method for the production of etoposide wherein 2,3 - diphenoxyacetyl -1-O-triethylsilyl - beta -D- glucopyranoside is condensed with 4'-phenoxyacetyl-4'-demethylepipodophyllotoxine.
AU36613/00A 1999-03-29 2000-03-29 Novel method for the production of etoposide Abandoned AU3661300A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9903876 1999-03-29
FR9903876A FR2791681B1 (en) 1999-03-29 1999-03-29 NEW PROCESS FOR THE PREPARATION OF ETOPOSIDE
PCT/FR2000/000774 WO2000058326A2 (en) 1999-03-29 2000-03-29 Novel method for the production of etoposide

Publications (1)

Publication Number Publication Date
AU3661300A true AU3661300A (en) 2000-10-16

Family

ID=9543737

Family Applications (1)

Application Number Title Priority Date Filing Date
AU36613/00A Abandoned AU3661300A (en) 1999-03-29 2000-03-29 Novel method for the production of etoposide

Country Status (6)

Country Link
EP (1) EP1165582B1 (en)
AT (1) ATE231159T1 (en)
AU (1) AU3661300A (en)
DE (1) DE60001226D1 (en)
FR (1) FR2791681B1 (en)
WO (1) WO2000058326A2 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658824B1 (en) * 1990-02-27 1992-07-03 Pf Medicament TRIS ACETYL-2 ", 3", 4 'ETHYLIDENE-4 ", 6" BETA-D-GLUCOPYRANOSIDES, THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF DEMETHYL-4' EPIPODOPHYLLOTOXIN ETHYLIDENE BETA-D-GLUCOPYRANOSIDE.
IT1250692B (en) * 1991-07-23 1995-04-21 PROCEDURE FOR THE PREPARATION OF DEMETYLEPIPODOPHYLOTOXY-BETA-D-GLUCOSIDES.

Also Published As

Publication number Publication date
ATE231159T1 (en) 2003-02-15
FR2791681B1 (en) 2001-06-22
WO2000058326A3 (en) 2001-02-01
WO2000058326A2 (en) 2000-10-05
FR2791681A1 (en) 2000-10-06
DE60001226D1 (en) 2003-02-20
EP1165582B1 (en) 2003-01-15
EP1165582A2 (en) 2002-01-02

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase