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AU3484499A - Reagents and methods for inhibiting furin protease activity - Google Patents

Reagents and methods for inhibiting furin protease activity

Info

Publication number
AU3484499A
AU3484499A AU34844/99A AU3484499A AU3484499A AU 3484499 A AU3484499 A AU 3484499A AU 34844/99 A AU34844/99 A AU 34844/99A AU 3484499 A AU3484499 A AU 3484499A AU 3484499 A AU3484499 A AU 3484499A
Authority
AU
Australia
Prior art keywords
reagents
methods
protease activity
furin protease
inhibiting furin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34844/99A
Inventor
Francois Jean
Gary Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oregon Health and Science University
Original Assignee
Oregon Health and Science University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon Health and Science University filed Critical Oregon Health and Science University
Publication of AU3484499A publication Critical patent/AU3484499A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU34844/99A 1998-04-08 1999-04-08 Reagents and methods for inhibiting furin protease activity Abandoned AU3484499A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8103498P 1998-04-08 1998-04-08
US60081034 1998-04-08
PCT/US1999/007776 WO1999051624A1 (en) 1998-04-08 1999-04-08 Reagents and methods for inhibiting furin protease activity

Publications (1)

Publication Number Publication Date
AU3484499A true AU3484499A (en) 1999-10-25

Family

ID=22161701

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34844/99A Abandoned AU3484499A (en) 1998-04-08 1999-04-08 Reagents and methods for inhibiting furin protease activity

Country Status (3)

Country Link
AU (1) AU3484499A (en)
CA (1) CA2327814A1 (en)
WO (1) WO1999051624A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1475435A1 (en) * 2003-05-09 2004-11-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Prohormone/proprotein-proteinase crystal structure and use thereof
CN109160888B (en) * 2018-10-09 2022-03-01 四川医立特生物医药有限公司 Amidino-containing symmetrical compound and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604201A (en) * 1993-01-08 1997-02-18 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization Methods and reagents for inhibiting furin endoprotease

Also Published As

Publication number Publication date
CA2327814A1 (en) 1999-10-14
WO1999051624A1 (en) 1999-10-14

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase