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AU3392684A - Nitrosourea derivatives. - Google Patents

Nitrosourea derivatives.

Info

Publication number
AU3392684A
AU3392684A AU33926/84A AU3392684A AU3392684A AU 3392684 A AU3392684 A AU 3392684A AU 33926/84 A AU33926/84 A AU 33926/84A AU 3392684 A AU3392684 A AU 3392684A AU 3392684 A AU3392684 A AU 3392684A
Authority
AU
Australia
Prior art keywords
formula
hydrogen
represent
hydrogen atom
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU33926/84A
Other versions
AU580009C (en
AU580009B2 (en
Inventor
Patrick Choay
Jean-Paul Fournier
Claude Monneret
Pierre Roger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DROPIC CIVILE DE GESTION DE DROITS DE PROPRIETE INDUSTRIELLE CHOAY Ste
Original Assignee
Dropic Soc Civ De Gestion De Droits De Propriete Industrielle Choay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dropic Soc Civ De Gestion De Droits De Propriete Industrielle Choay filed Critical Dropic Soc Civ De Gestion De Droits De Propriete Industrielle Choay
Publication of AU3392684A publication Critical patent/AU3392684A/en
Application granted granted Critical
Publication of AU580009B2 publication Critical patent/AU580009B2/en
Publication of AU580009C publication Critical patent/AU580009C/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Nitrosourea derivatives, process for their preparation and pharmaceutical compositions containing them. The nitrosourea derivatives of the invention correspond to the formula (I), in which: R can represent a hydrogen atom or an alkyl group from 1 to 30 carbon atoms, X represents a hydroxy group or an -NR1R2 group, Y represents a hydrogen atom, a hydroxy group or an -NR'1R'2 group, where R1 and/or R'1 each represent a hydrogen atom or formula (II), Hal being a halogen, and R2 and/or R'2 can each represent a hydrogen atom or an alkyl group comprising from 1 to 6 carbon atoms, R' and R'' can represent hydrogen or OH, provided that at least, X represents formula (III), with R1 representing formula (IV) or Y represents formula (V) with R'1 representing formula (VI) and provided that, either R' represents hydrogen or R'' represents hydrogen, and R' and R'' cannot be simultaneously hydrogen atoms. These compounds present an antitumor activity.
AU33926/84A 1983-08-30 1984-08-29 Nitrosourea derivatives. Ceased AU580009C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8313878A FR2551068B1 (en) 1983-08-30 1983-08-30 NOVEL NITROSOURES DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THEM
FR8313878 1983-08-30

Publications (3)

Publication Number Publication Date
AU3392684A true AU3392684A (en) 1985-03-29
AU580009B2 AU580009B2 (en) 1988-12-22
AU580009C AU580009C (en) 1990-07-19

Family

ID=

Also Published As

Publication number Publication date
ES8602031A1 (en) 1985-12-01
CA1257587A (en) 1989-07-18
WO1985001050A1 (en) 1985-03-14
DE3481305D1 (en) 1990-03-15
PT79158B (en) 1986-08-19
ATE50264T1 (en) 1990-02-15
EP0143675A1 (en) 1985-06-05
IL72817A (en) 1989-09-10
IL72817A0 (en) 1984-11-30
GR80249B (en) 1984-12-14
ES535903A0 (en) 1985-12-01
DK194585A (en) 1985-04-30
FR2551068A1 (en) 1985-03-01
NZ209397A (en) 1988-04-29
KR920001690B1 (en) 1992-02-22
FR2551068B1 (en) 1986-03-21
DK194585D0 (en) 1985-04-30
PT79158A (en) 1984-09-01
AU580009B2 (en) 1988-12-22
EP0143675B1 (en) 1990-02-07
JPS60502105A (en) 1985-12-05
ZA846783B (en) 1985-04-24
KR850700031A (en) 1985-10-21

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