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AU3295900A - Amyotropic lateral sclerosis treatment with a combination of riluzole and an ampa receptor antagonist - Google Patents

Amyotropic lateral sclerosis treatment with a combination of riluzole and an ampa receptor antagonist

Info

Publication number
AU3295900A
AU3295900A AU32959/00A AU3295900A AU3295900A AU 3295900 A AU3295900 A AU 3295900A AU 32959/00 A AU32959/00 A AU 32959/00A AU 3295900 A AU3295900 A AU 3295900A AU 3295900 A AU3295900 A AU 3295900A
Authority
AU
Australia
Prior art keywords
riluzole
combination
receptor antagonist
lateral sclerosis
ampa receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU32959/00A
Inventor
Andrees Bohme
Alain Boireau
Thierry Canton
Jeremy Pratt
Jean-Marie Stutzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9903100A external-priority patent/FR2790670A1/en
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU3295900A publication Critical patent/AU3295900A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU32959/00A 1999-03-12 2000-03-10 Amyotropic lateral sclerosis treatment with a combination of riluzole and an ampa receptor antagonist Abandoned AU3295900A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR9903100A FR2790670A1 (en) 1999-03-12 1999-03-12 Treatment or prevention of amyotrophic lateral sclerosis, using synergistic combination of riluzole and AMPA receptor antagonist, e.g. 5H,10H-imidazo (1,2-a) indeno (1,2-e) pyrazin-4-one derivative
FR9903100 1999-03-12
US12931899P 1999-04-14 1999-04-14
US60129318 1999-04-14
PCT/FR2000/000590 WO2000054772A1 (en) 1999-03-12 2000-03-10 Amyotropic lateral sclerosis treatment with a combination of riluzole and an ampa receptor antagonist

Publications (1)

Publication Number Publication Date
AU3295900A true AU3295900A (en) 2000-10-04

Family

ID=26234859

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32959/00A Abandoned AU3295900A (en) 1999-03-12 2000-03-10 Amyotropic lateral sclerosis treatment with a combination of riluzole and an ampa receptor antagonist

Country Status (4)

Country Link
EP (1) EP1161238A1 (en)
JP (1) JP2002539162A (en)
AU (1) AU3295900A (en)
WO (1) WO2000054772A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1642572A (en) * 2002-03-29 2005-07-20 山之内制药株式会社 Therapeutic agent for glioblastoma
US7045527B2 (en) 2002-09-24 2006-05-16 Amgen Inc. Piperidine derivatives
EP1798232A1 (en) * 2005-12-08 2007-06-20 Hybrigenics S.A. Inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications
MX2008007195A (en) * 2005-12-08 2008-09-10 Hybrigenics Sa Inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications.
WO2010113225A1 (en) * 2009-03-30 2010-10-07 Yutoku Pharmaceutical Industries Co., Ltd. Riluzole-containing transdermal patch

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2722789B1 (en) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa IMIDAZO (1,2-A) INDENO (1,2-E) PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
US5780489A (en) * 1996-08-21 1998-07-14 Brooks; Benjamin Rix Method for treating amyotrophic lateral sclerosis
EP1011656A2 (en) * 1996-11-05 2000-06-28 Head Explorer ApS A method for treating tension-type headache
BR9906821A (en) * 1998-01-09 2000-10-17 Mor Research Applic Ltd Pharmaceutical composition and process to improve levodopa-induced dyskinesia and tardive dyskinesia, and use of riluzole for the preparation of a pharmaceutical composition

Also Published As

Publication number Publication date
JP2002539162A (en) 2002-11-19
WO2000054772A1 (en) 2000-09-21
EP1161238A1 (en) 2001-12-12

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase