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AU3276193A - 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists - Google Patents

3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists

Info

Publication number
AU3276193A
AU3276193A AU32761/93A AU3276193A AU3276193A AU 3276193 A AU3276193 A AU 3276193A AU 32761/93 A AU32761/93 A AU 32761/93A AU 3276193 A AU3276193 A AU 3276193A AU 3276193 A AU3276193 A AU 3276193A
Authority
AU
Australia
Prior art keywords
phenyl
ureido
nmr
oxo
benzazepin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU32761/93A
Other languages
English (en)
Inventor
John A. Lowe Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Publication of AU3276193A publication Critical patent/AU3276193A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU32761/93A 1992-01-27 1992-12-16 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists Abandoned AU3276193A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82567792A 1992-01-27 1992-01-27
US825677 1992-01-27

Publications (1)

Publication Number Publication Date
AU3276193A true AU3276193A (en) 1993-09-01

Family

ID=25244657

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32761/93A Abandoned AU3276193A (en) 1992-01-27 1992-12-16 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists

Country Status (19)

Country Link
EP (1) EP0625145A1 (pt)
JP (1) JPH07503465A (pt)
KR (1) KR950700257A (pt)
CN (1) CN1074903A (pt)
AU (1) AU3276193A (pt)
BR (1) BR9207071A (pt)
CA (1) CA2117367A1 (pt)
CZ (1) CZ391092A3 (pt)
FI (1) FI943513L (pt)
HU (1) HUT70496A (pt)
IL (1) IL104472A0 (pt)
MX (1) MX9300409A (pt)
NO (1) NO942775L (pt)
NZ (1) NZ245759A (pt)
RU (1) RU94038063A (pt)
TW (1) TW213901B (pt)
WO (1) WO1993015059A1 (pt)
YU (1) YU4393A (pt)
ZA (1) ZA93582B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097688A1 (es) * 1993-07-14 1997-04-01 Pfizer Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
ES2132401T3 (es) * 1993-07-26 1999-08-16 Pfizer Tetrahidro-1h-benzazepinonas y hexahidroazepinonas como antagonistas selectivos del receptor colecistoquinina-b.
AU681924B2 (en) * 1993-11-22 1997-09-11 Merck & Co., Inc. 3-acylaminobenzazepines
US5453424A (en) * 1993-11-22 1995-09-26 Merck & Co., Inc. Furanodiazepines
MX9702507A (es) * 1994-10-04 1997-07-31 Pfizer Nuevos intermedios y procedimientos para preparar antagonistas cck.
WO1996011689A1 (en) * 1994-10-14 1996-04-25 Glaxo Wellcome Spa Use of cck-b receptor antagonists for the treatment of sleep disorders
DE10153348A1 (de) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte Benzo(b)azepin-2-on-Verbindungen
US20090042858A1 (en) * 2005-06-16 2009-02-12 Paul Barsanti Lactam containing hcv inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166357A3 (en) * 1984-06-26 1988-10-26 Merck & Co. Inc. Benzofused lactams and pharmaceutical compositions containing them
US4767756A (en) * 1987-07-17 1988-08-30 E. R. Squibb & Sons, Inc. 3-substituted benzazepines
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck

Also Published As

Publication number Publication date
HU9402195D0 (en) 1994-09-28
JPH07503465A (ja) 1995-04-13
ZA93582B (en) 1994-07-27
NO942775L (no) 1994-09-20
HUT70496A (en) 1995-10-30
YU4393A (sr) 1996-01-09
FI943513A7 (fi) 1994-07-26
CA2117367A1 (en) 1993-08-05
KR950700257A (ko) 1995-01-16
TW213901B (pt) 1993-10-01
EP0625145A1 (en) 1994-11-23
FI943513A0 (fi) 1994-07-26
BR9207071A (pt) 1995-12-05
MX9300409A (es) 1993-07-01
FI943513L (fi) 1994-07-26
CN1074903A (zh) 1993-08-04
CZ391092A3 (en) 1994-01-19
WO1993015059A1 (en) 1993-08-05
RU94038063A (ru) 1996-05-27
IL104472A0 (en) 1993-05-13
NZ245759A (en) 1997-06-24
NO942775D0 (no) 1994-07-26

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