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AU3166299A - Arginine peptide analogs useful as fibroblast growth factor antagonists - Google Patents

Arginine peptide analogs useful as fibroblast growth factor antagonists

Info

Publication number
AU3166299A
AU3166299A AU31662/99A AU3166299A AU3166299A AU 3166299 A AU3166299 A AU 3166299A AU 31662/99 A AU31662/99 A AU 31662/99A AU 3166299 A AU3166299 A AU 3166299A AU 3166299 A AU3166299 A AU 3166299A
Authority
AU
Australia
Prior art keywords
growth factor
fibroblast growth
peptide analogs
factor antagonists
analogs useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU31662/99A
Inventor
Vitukudi Narayanaiyengar Balaji
Ming Fai Chan
Ramnarayan Kalyanaraman
Laura Schove
Ventkatachalapathi Yalamoori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of AU3166299A publication Critical patent/AU3166299A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU31662/99A 1998-04-09 1999-04-07 Arginine peptide analogs useful as fibroblast growth factor antagonists Abandoned AU3166299A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5800298A 1998-04-09 1998-04-09
US09058002 1998-04-09
PCT/JP1999/001844 WO1999052936A2 (en) 1998-04-09 1999-04-07 Arginine peptide analogs useful as fibroblast growth factor antagonists

Publications (1)

Publication Number Publication Date
AU3166299A true AU3166299A (en) 1999-11-01

Family

ID=22014057

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31662/99A Abandoned AU3166299A (en) 1998-04-09 1999-04-07 Arginine peptide analogs useful as fibroblast growth factor antagonists

Country Status (2)

Country Link
AU (1) AU3166299A (en)
WO (1) WO1999052936A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0019357D0 (en) 2000-08-07 2000-09-27 Melacure Therapeutics Ab Novel phenyl guanidines
CA2686735A1 (en) 2007-05-04 2008-11-13 Mdrna, Inc. Amino acid lipids and uses thereof
AU2015282627B2 (en) 2014-06-30 2020-04-02 Glykos Finland Oy Saccharide derivative of a toxic payload and antibody conjugates thereof
JP6994939B2 (en) * 2014-07-02 2022-02-04 インフレクティス・バイオサイエンス New Therapeutic Use of Benzylidene Guanidine Derivatives for the Treatment of Proteinopathy
CN111233973A (en) * 2020-02-21 2020-06-05 重庆医药高等专科学校 Synthesis method and application of arginine derivative Pro-Phe-Arg-AMC

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB774794A (en) * 1953-01-30 1957-05-15 Bayer Ag Quinone condensation products
BE604520A (en) * 1960-06-02 1961-12-01 Ciba Geigy Pharmaceuticals containing guanylic hydrazones of O- and m-aminophenyl-alkyl ketones
FR2549049B1 (en) * 1983-07-13 1986-06-20 Chauvin Blache Lab NEW AMIDINES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
ES2039161B1 (en) * 1992-01-13 1994-04-01 Inst Investigacion Desarrollo PROCEDURE FOR OBTAINING NEW HYDRAZONES WITH ANTIPROLIFERATIVE ACTIVITY.

Also Published As

Publication number Publication date
WO1999052936A3 (en) 2000-01-13
WO1999052936A2 (en) 1999-10-21

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase