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AU3023201A - Dispersion comprising a non-ionic emulsifier - Google Patents

Dispersion comprising a non-ionic emulsifier

Info

Publication number
AU3023201A
AU3023201A AU30232/01A AU3023201A AU3023201A AU 3023201 A AU3023201 A AU 3023201A AU 30232/01 A AU30232/01 A AU 30232/01A AU 3023201 A AU3023201 A AU 3023201A AU 3023201 A AU3023201 A AU 3023201A
Authority
AU
Australia
Prior art keywords
dispersion
ionic emulsifier
consistin
binder
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU30232/01A
Inventor
Johanna Eisele
Stefan Grimm
Christian Meier
Hans-Ulrich Petereit
Michael Schnabel
Klaus Schultes
Thomas Sufke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm GmbH Darmstadt
Original Assignee
Roehm GmbH Darmstadt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm GmbH Darmstadt filed Critical Roehm GmbH Darmstadt
Publication of AU3023201A publication Critical patent/AU3023201A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/12—Polymerisation in non-solvents
    • C08F2/16—Aqueous medium
    • C08F2/22—Emulsion polymerisation
    • C08F2/24—Emulsion polymerisation with the aid of emulsifying agents
    • C08F2/30—Emulsion polymerisation with the aid of emulsifying agents non-ionic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C08F220/1802—C2-(meth)acrylate, e.g. ethyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C08F220/1803—C3-(meth)acrylate, e.g. (iso)propyl (meth)acrylate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to a dispersion suitable for use as coating agent and binder for pharmaceutical forms, having a solids content of 10-70% by weight consistin
AU30232/01A 2000-03-10 2001-02-02 Dispersion comprising a non-ionic emulsifier Abandoned AU3023201A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10011447A DE10011447A1 (en) 2000-03-10 2000-03-10 New stable (meth)acrylate copolymer emulsion containing nonionic emulsifier, useful as coating and binding agent for medicaments, is not subject to emulsifier crystallization
DE10011447 2000-03-10
PCT/EP2001/001108 WO2001068767A1 (en) 2000-03-10 2001-02-02 Dispersion comprising a non-ionic emulsifier

Publications (1)

Publication Number Publication Date
AU3023201A true AU3023201A (en) 2001-09-24

Family

ID=7634069

Family Applications (1)

Application Number Title Priority Date Filing Date
AU30232/01A Abandoned AU3023201A (en) 2000-03-10 2001-02-02 Dispersion comprising a non-ionic emulsifier

Country Status (11)

Country Link
US (1) US6998140B2 (en)
EP (1) EP1200521B1 (en)
JP (1) JP4944334B2 (en)
AT (1) ATE282067T1 (en)
AU (1) AU3023201A (en)
CA (1) CA2386932C (en)
DE (2) DE10011447A1 (en)
DK (1) DK1200521T3 (en)
ES (1) ES2228799T3 (en)
PL (1) PL199225B1 (en)
WO (1) WO2001068767A1 (en)

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DE10220470A1 (en) * 2002-04-30 2003-11-20 Roehm Gmbh ph-sensitive polymer
DE19961334A1 (en) * 1999-12-17 2001-06-21 Roehm Gmbh Injection molding process for neutral and acid group-containing (meth) acrylate copolymers
DE10043868A1 (en) * 2000-09-04 2002-04-04 Roehm Gmbh PMMA molding compounds with improved impact resistance
WO2002068557A1 (en) * 2001-02-07 2002-09-06 Röhm GmbH & Co. KG Hot sealing compound for aluminum foils applied to polypropylene and polystyrene
DE10127134A1 (en) * 2001-06-05 2002-12-12 Roehm Gmbh Production of injection molded shaped articles, especially for retarded drug release, by blending (meth)acrylate copolymer with plasticizer and other additives, degassing and molding
DE10204890A1 (en) * 2002-02-06 2003-08-14 Roehm Gmbh Impact-resistant molding compound and molded body
DE10208335A1 (en) * 2002-02-27 2003-09-04 Roehm Gmbh Pharmaceutical form and process for its preparation
DE10214002A1 (en) * 2002-03-27 2003-10-09 Roehm Gmbh Pharmaceutical formulation for the active substance budesonide
DE10243062A1 (en) * 2002-09-16 2004-03-25 Röhm GmbH & Co. KG A sanitary material made from thermoplastic polymethyl methacrylate molding material useful for sanitary material resistant to hot water,which is crack resistant, cheap to produce, and can be recycled
DE10250543A1 (en) * 2002-10-29 2004-05-19 Röhm GmbH & Co. KG Multilayer dosage form
DE10260089A1 (en) * 2002-12-19 2004-07-01 Röhm GmbH & Co. KG Process for the preparation of aqueous dispersions
DE10260065A1 (en) * 2002-12-19 2004-07-01 Röhm GmbH & Co. KG Core-shell particles for toughening of poly (meth) acrylate molding compounds
MXPA04010956A (en) * 2003-01-30 2005-01-25 Roehm Gmbh Pharmaceutical dosage form and method for the production thereof.
DE10345045A1 (en) * 2003-09-26 2005-04-14 Röhm GmbH & Co. KG Surface coating of materials, e.g. to form a protective layer, involves laminating with a film made from a mixture of methyl methacrylate-based polymer and an acrylic copolymer with reactive comonomer units
DE10349144A1 (en) * 2003-10-17 2005-05-12 Roehm Gmbh Polymer mixture for injection mouldings with a matt surface, e.g. exterior vehicle parts, comprises an acrylic matrix, a crosslinked acrylic impact modifier and plastic particles with a specified range of particle sizes
MX2007008855A (en) * 2003-10-18 2008-03-13 Roehm Gmbh Core and shell particle for modifying impact resistance of a mouldable poly(meth)acrylate material.
DE10351535A1 (en) * 2003-11-03 2005-06-09 Röhm GmbH & Co. KG Multilayer film of (meth) acrylate copolymer and polycarbonate
DE10354379A1 (en) 2003-11-20 2005-06-23 Röhm GmbH & Co. KG A molding composition containing a matting agent
US20050202079A1 (en) * 2004-03-15 2005-09-15 Mylan Pharmaceuticals Inc. Novel orally administrable formulation of nitrofurantoin and a method for preparing said formulation
US9498563B2 (en) * 2004-04-23 2016-11-22 Boston Scientific Scimed, Inc. Medical articles having therapeutic-agent-containing regions formed from coalesced polymer particles
DE102004022540A1 (en) * 2004-05-05 2005-12-08 Röhm GmbH & Co. KG Molding composition for moldings with high weather resistance
DE102004045296A1 (en) * 2004-09-16 2006-03-23 Röhm GmbH & Co. KG Use of polyalkyl (meth) acrylate bead polymers and molding compound for the production of extruded molded parts with a matted surface
DE102004058083A1 (en) 2004-12-01 2006-06-08 Röhm GmbH & Co. KG Covered colored, infrared-reflecting plastic molding compound
JP4537870B2 (en) * 2005-03-16 2010-09-08 ガンツ化成株式会社 A method for producing an alkyl (meth) acrylate copolymer emulsion.
CN101137701B (en) * 2005-04-18 2011-02-09 赢创罗姆有限公司 Thermoplastic molding material and molding elements containing nanometric inorganic particles, method for making said molding material and said molding elements, and uses thereof
DE102005021335A1 (en) * 2005-05-04 2006-11-09 Röhm Gmbh Process for the preparation of bead polymers having a mean particle size in the range of 1 .mu.m to 40 .mu.m, and molding compositions and moldings comprising bead polymer
DE102005055793A1 (en) 2005-11-21 2007-05-24 Röhm Gmbh Transparent TPU (thermoplastic polyurethanes) / PMMA (polymethyl (meth) acrylate) Blends with improved impact resistance
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
DE102006029613A1 (en) * 2006-06-26 2007-12-27 Röhm Gmbh Transparent plastic composite
US20080035703A1 (en) * 2006-08-09 2008-02-14 Daewoong Suh Oxidation resistant solder preform
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
DE102007005432A1 (en) * 2007-01-30 2008-07-31 Evonik Röhm Gmbh Molding material useful for making shaped products comprises a (meth)acrylate (co)polymer and ceramic beads
DE102007009243A1 (en) 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets with a drug matrix and a polymer coating, and a method for producing the pellets
DE102007009242A1 (en) 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets with enteric-coated matix
DE102007026201A1 (en) * 2007-06-04 2008-12-11 Evonik Röhm Gmbh Colored composition with increased stress cracking resistance
DE102007026200A1 (en) * 2007-06-04 2008-12-11 Evonik Röhm Gmbh Composition with increased stress cracking resistance
DE102007028601A1 (en) 2007-06-19 2008-12-24 Evonik Röhm Gmbh Reactive mixture for coating moldings by means of reaction injection molding and coated molding
DE102007029263A1 (en) * 2007-06-22 2008-12-24 Evonik Röhm Gmbh PMMA / PVDF film with particularly high weather resistance and high UV protection
DE102007051482A1 (en) * 2007-10-25 2009-04-30 Evonik Röhm Gmbh Process for the production of coated moldings
DE102008001231A1 (en) * 2008-04-17 2009-10-22 Evonik Röhm Gmbh Flameproof PMMA molding compound
DE102008001695A1 (en) * 2008-05-09 2009-11-12 Evonik Röhm Gmbh Poly (meth) acrylimides with improved optical and color properties, especially under thermal stress
RU2013111605A (en) 2010-08-18 2014-09-27 Эвоник Рем ГмбХ GASTRIC JUICE RESISTANT PHARMACEUTICAL OR NUTRICEUTIC COMPOSITION CONTAINING ONE OR MORE ALGINIC ACID SALTS
SI2720682T1 (en) 2011-06-17 2017-05-31 Evonik Roehm Gmbh Coating composition suitable for pharmaceutical or nutraceutical dosage forms
US9775815B2 (en) 2011-06-17 2017-10-03 Evonik Roehm Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
SG11201400224PA (en) * 2011-08-30 2014-08-28 Sumitomo Seika Chemicals Method for producing water-absorbing resin, and water-absorbing resin obtained by same
MX355662B (en) 2012-08-27 2018-04-25 Evonik Roehm Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol.
HUE031603T2 (en) 2012-08-27 2017-07-28 Evonik Roehm Gmbh Pharmaceutical or nutraceutical composition with sustained release characteristic and with resistance against the influence of ethanol
MX2015010449A (en) 2013-02-13 2015-10-30 Evonik Roehm Gmbh Multiparticulate pharmaceutical composition comprising a multitude of two kinds of pellets.
US9895318B2 (en) 2014-02-17 2018-02-20 Evonik Roehm Gmbh Pharmaceutical or nutraceutical composition with sustained release characteristic and with resistance against the influence of ethanol
HUE049247T2 (en) 2014-11-26 2020-09-28 Evonik Operations Gmbh Pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
ES2838816T3 (en) 2015-06-05 2021-07-02 Evonik Operations Gmbh Pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
IL274579B2 (en) 2017-11-17 2025-04-01 Evonik Operations Gmbh Process for preparing a coated hard shell capsule
WO2020229178A1 (en) 2019-05-15 2020-11-19 Evonik Operations Gmbh Process for preparing filled hard-shell capsules with (meth)acrylate copolymer based coatings with a capsule-filling machine
CN113950321A (en) 2019-06-13 2022-01-18 赢创运营有限公司 Powder composition comprising copolymer mixture and water-soluble cellulose
JP2024521755A (en) 2021-05-25 2024-06-04 エボニック オペレーションズ ゲーエムベーハー Hard shell capsule prevents gastric juices from entering
WO2022248334A1 (en) 2021-05-25 2022-12-01 Evonik Operations Gmbh Hard shell capsules with modified release coating
EP4176874A1 (en) 2021-11-09 2023-05-10 Evonik Operations GmbH Pharmaceutical or nutraceutical composition with an alcohol resistant single layer coating system
MX2024011195A (en) 2022-03-15 2024-09-18 Evonik Operations Gmbh Pre-functionalized hard shell capsule with accelerated drug release at ph value 5 to 5.5.
WO2023214016A1 (en) 2022-05-06 2023-11-09 Evonik Operations Gmbh Dosage form with drug release at ph 3 to 6 using double coating system with at least one release acceleration agent

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Also Published As

Publication number Publication date
US6998140B2 (en) 2006-02-14
EP1200521B1 (en) 2004-11-10
DK1200521T3 (en) 2005-03-14
JP4944334B2 (en) 2012-05-30
EP1200521A1 (en) 2002-05-02
CA2386932C (en) 2010-08-24
ES2228799T3 (en) 2005-04-16
CA2386932A1 (en) 2001-09-20
DE50104475D1 (en) 2004-12-16
PL350610A1 (en) 2003-01-27
DE10011447A1 (en) 2001-09-20
US20030060381A1 (en) 2003-03-27
WO2001068767A1 (en) 2001-09-20
JP2003526724A (en) 2003-09-09
PL199225B1 (en) 2008-08-29
ATE282067T1 (en) 2004-11-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase