[go: up one dir, main page]

AU2809899A - Dosing beverage with a bacteria formulation - Google Patents

Dosing beverage with a bacteria formulation Download PDF

Info

Publication number
AU2809899A
AU2809899A AU28098/99A AU2809899A AU2809899A AU 2809899 A AU2809899 A AU 2809899A AU 28098/99 A AU28098/99 A AU 28098/99A AU 2809899 A AU2809899 A AU 2809899A AU 2809899 A AU2809899 A AU 2809899A
Authority
AU
Australia
Prior art keywords
containers
formulated
beverage
mixture
probiotic bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU28098/99A
Inventor
Maxwell John Strong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MENDEL INSTITUTE FOR NUTRACEUTICAL RESEARCH INC
Original Assignee
Mendel Institute For Nutraceutical Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU59357/98A external-priority patent/AU5935798A/en
Application filed by Mendel Institute For Nutraceutical Research Inc filed Critical Mendel Institute For Nutraceutical Research Inc
Priority to AU28098/99A priority Critical patent/AU2809899A/en
Publication of AU2809899A publication Critical patent/AU2809899A/en
Abandoned legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)

Description

AUSTRALIA
Patents Act 1990 COMPLETE SPECIFICATION DIVISIONAL PATENT Applicant: THE MENDEL INSTITUTE FOR NUTRACEUTICAL RESEARCH,
INC
Invention Title: DOSING BEVERAGE WITH A BACTERIA FORMULATION The following statement is a full description of this invention, including the best method of performing it known to me/us: DOSING BEVERAGE WITH A BACTERIA
FORMULATION
FIELD OF THE INVENTION This invention relates to a method of and apparatus for use in adding a probiotic bacteria formulation to a beverage.
The invention has been developed primarily in the context of dosing milk liquid milk in its various possible forms, including soy milk) with a probiotic bacteria formulation and the invention is hereinafter described in this context. However, it will be understood that the invention does have broader application, to the dosing of other beverages and to dosing with a formulation that contains substances additional to probiotic bacteria.
BACKGROUND OF THE INVENTION The benefits of dosing food products, including milk products, with bacteria are well known. Documented examples of the beneficial effects of the use of certain bacterial strains Lactobacillus and Bifidobacterium strains) include their treatment of various types of diarrhoea, the alleviation of the gastrointestinal side effects of antibiotic treatment, the alleviation of lactose intolerance, the relief of constipation and the general balancing and stabilisation of intestinal integrity. More recent studies have indicated that, for some strains, immune-enhancing and vaccine-adjuvant effects have been obtained, and an ability to lower serum cholesterol has been observed. Some bacterial strains also have shown an ability to suppress tumour growth and to remove or modify dietary carcinogens. In addition, some strains have also been shown to produce vitamins and, in particular, the important B group vitamins including folic acid. Other benefits to be derived from the administration of bacteria are enhanced bioabsorption of minerals, particularly J:\Speci\300 399\300 349\34296.doc 11/05/99 calcium and iron from dietary components. These therapeutic effects are in addition to the well-known nutritional effects that flow from improvement in the digestion of proteins and fats in food products.
Health promoting foods, such as yoghurt, that contain probiotic and, in some cases, prebiotic bacteria currently are available. However, these food products do not find favour with some consumers because of their sour, lactic taste, and the addition of a sweetening agent is often undesirable.
It is recognised by persons who have an interest in public health that a broadly based supplementation of probiotic bacteria intake would provide community benefit. In this context consideration has been given to the introduction of probiotic bacteria into milk, this being one of the most widely consumed food products in many communities.
A probiotic therapeutic benefit may be obtained from a minimum daily intake in the order of 1 x 109 colony forming units (cfu) but, because of the extremely small mass that is represented by this volume, controlled community administration presents a significant problem. Some milks have been made available which contain lactic bacterial cultures. However they are produced by adding a very small dose (by volume) of the cultures to a large volume of milk in a refrigerated mixing vessel. The milk containing the lactic cultures is dispensed into individual retailing sized containers by way of filling machinery but, because of the relatively small volume of bacteria present in the milk supply, the statistical likelihood of a therapeutic amount of probiotic bacteria being dosed into each container is extremely low.
The present invention seeks to provide a solution to this problem.
J:\Speci\300 399\300 349\34296.doc 11/05/99 SUMMARY OF THE INVENTION Broadly defined, the present invention provide a method of adding a probiotic bacteria to a beverage and which comprises the steps of: a. formulating a mixture of the bacteria and a biologically acceptable beverage-miscible excipient, b. delivering empty beverage containers to a filling station and conveying the containers serially through the filling station, c. delivering a predetermined quantity of the formulated mixture to each container whilst it is positioned within the filling station and, as a separate operation, d. injecting a predetermined quantity of the beverage into each of the containers.
The formulated mixture containing the probiotic bacteria and excipient may be delivered to each container in a liquid form or in a tablet form. However, in either case, the beverage is injected separately from delivery of the formulated mixture, always from separate sources and normally at different instants in time.
The containers into which the bacteria/excipient formulation and the beverage are delivered may comprise glass or plastic bottle-type containers or cardboard containers of the type in which milk and fruit beverages frequently are marketed.
The beverage delivering mechanism may take any one of the forms that currently are employed for delivering beverages to containers. These normally are integrated in high speed production lines in which filling and container closing or capping processes occur and, in order to minimise any reduction in the transport velocity of a production line, the containers may temporarily be diverted from a main conveyor system to a secondary conveyor system. Delivery J:\Speci\300 399\300 349\34296.doc 11/05/99 of the liquid or tablet form bacteria/excipient formulation to successive ones of the containers may then be effected whilst the containers are conveyed by the secondary conveyor, without interfering with the overall system transport velocity.
PREFERRED FEATURES OF THE INVENTION The beverage preferably is injected into the beverage containers at the same time as or after delivery of the formulated mixture, in order to promote dispersion of the formulated mixture throughout the beverage.
The probiotic bacteria preferably is selected from a group comprising lactobacilli and bifidobacteria.
The probiotic bacteria most preferably comprises lactobacilli acidophillus, bifidobacteria bifidus and/or bifidobacteria infantis.
The formulated mixture preferably includes a blend of the probiotic bacteria and a prebiotic substance, most preferably a prebiotic soluble dietary fibre selected for promoting growth of the probiotic bacteria in the human gastro-intestinal tract.
The prebiotic substance, when included, may comprise an oligosaccharide and, preferably, fructooligosaccharide.
In circumstances where the beverage to which the bacteria/excipient formulation is added comprises milk, the excipient preferably comprises milk, an oligosaccharide, lactose or maltodextrin.
As indicated previously, the probiotic bacteria may be added to beverages other than milk, for example fruit juices. In these circumstances the excipient preferably J:\Speci\300 399\300 349\34296.doc 11/05/99 comprises a fruit juice or an oligosaccharide.
The formulated mixture containing the probiotic bacteria may include therapeutically or prophylatically beneficial additives, for example immunoglobulins or phytoestrogens and other ingredients of the type commonly added to milk and other beverages.
EXAMPLES OF BACTERIA/EXCIPIENT
FORMULATIONS
The following example is provided in relation to the formulating and mixing of material to be added in a liquid form to milk.
To 10 litres of pasteurised milk there are added A stabilised probiotic bacteria consisting of bifidobacterium bifidum 12 x 1012cfu lactobacillus acidophillus 4 x 1012cfu.
(ii) Prebiotic dietary fibre consisting of fructooligosaccharide 2 x 10 3 gms.
The components are aseptically mixed until solids are fully dissolved. The resultant solution is supplied to a reservoir of an injector mechanism which is controlled to deliver the solution to milk containers in the amount of per litre of milk to be dispensed into the containers.
After receiving the solution, each container is moved forward to a milk dispensing station where it is filled to the required level with milk.
Each container of milk containing the probiotic bacteria and solubilised prebiotic fructooligosaccharide is then closed and refrigerated prior to distribution.
The following example is provided in relation to the J:\Speci\300 399\300 349\34296.doc 11/05/99 formulating and mixing of material to be added in tablet form (at the rate of one tablet per litre of milk) to pasteurised milk.
A tabletting mixture containing the following is prepared: Stabilised probiotic bacteria consisting of bifidobacterium bifidus 60 x 101cfu lactobacillus acidophilus 20 x 10 12 cfu.
(ii) Prebiotic dietary fibre excipient consisting of compressable, soluble fructooligosaccharide x 10 3 gms.
The ingredients are dry-blended and fed to the hopper of a tablet forming machine which is fitted with a die that is sized and constructed to produce individual tablets having substantially uniform weight of 3 gms.
The tables are fed to a bulk hopper of a depositing mechanism that is arranged to dispense one tablet into each of a succession of one-litre containers that are conveyed through the depositing mechanism en route to a milk dispensing station.
After receiving one tablet, each container is moved into the milk dispensing station where it receives one litre of pasteurised milk.
Each container of milk containing the probiotic bacteria and solubilised prebiotic fructooligosaccharide is then closed and refrigerated prior to distribution.
The following example is provided in relation to the formulating and mixing of material to be added in liquid form to a beverage in the form of orange juice.
J:\Speci\300 399\300 349\34296.doc 11/05/99 To 10 litres of sterile water there is added Stabilised probiotic bacterium consisting of bifidobacterium bifidum 12 x 10 12 cfu lactobacillus acidophillus 4 x 1012cfu.
(ii) Prebiotic dietary fibre consisting of fructooligosaccharide 2 x 10 3 gms.
(iii) Orange juice concentrate 10 litres.
The components are asceptically mixed until solids are fully dissolved. The resultant solution is supplied to a reservoir of an injector mechanism which is controlled to deliver the solution to beverage containers in the amount of 10 ml of the solution per litre of beverage to be dispensed into the containers.
The containers are then advanced to a beverage filling station and, assuming that each container has a 1 litre capacity, beverage in the amount of 990 ml of orange juice is dispensed into the container.
Each container of beverage containing the probiotic bacteria and solubilised prebiotic material is then closed and conveyed to cold storage prior to distribution.
The following example is provided in relation to the formulating and mixing of material to be added in tablet form to a beverage in the form of orange juice.
A tabletting mixture containing the following is prepared: Stabilised probiotic bacteria consisting of bifidobacterium bifidus 60 x 102cfu lactobacillus acidophilus 20 x 1012cfu.
(ii) Prebiotic dietary fibre excipient consisting of J:\Speci\300 399\300 349\34296.doc 11/05/99 compressable, soluble fructooligosaccharide x 10 3 gms.
The ingredients are dry-blended and fed to the hopper of a tablet forming machine which is fitted with a die that is sized and constructed to produce individual tablets having substantially uniform weight of 3 gms.
The tablets are fed to a bulk hopper of a depositing mechanism that is arranged to dispense one tablet into each of a succession of one-litre containers that are conveyed through the depositing mechanism en route to a beverage dispensing station.
After receiving one tablet, each container is moved into the beverage dispensing station where it receives one litre of orange juice.
Each container of orange juice containing the probiotic bacteria and solubilised prebiotic fructooligosaccharide is then closed and conveyed to cold storage prior to distribution.
DETAILED DESCRIPTION OF APPARATUS FOR DELIVERING BACTERIA/EXCIPIENT FORMULATION The invention will be more fully understood from the following description of a preferred embodiment of an apparatus for use in delivering a bacteria/excipient formulation to beverage containers. The description is provided with reference to the accompanying schematic drawing.
The apparatus as illustrated in the drawing is intended for use in delivering a liquid form bacteria/excipient formulation into moulded plastics beverage containers The containers are delivered to the apparatus by a primary J:\Speci\300 399\300 349\34296.doc 11/05/99 conveyor 11 which forms a part of a high speed container filling/capping station. Although three only containers are shown, the apparatus would normally be operated to receive tightly bunched containers by way of the conveyor 11, and twelve containers 10 would normally be positioned on a carousel-type secondary conveyor 12 at any one point in time.
Empty containers 10 are delivered to the apparatus in the direction of arrow 13 and are deflected off the primary conveyor 11 by an in-feed starwheel mechanism 14. That is, the empty containers are deflected onto a lower rotary platform 15 of the carousel 12 and they are moved in a circular path until they meet an out-feed starwheel mechanism 16 which is driven to redeflect the containers back onto the primary conveyor 11.
Having been directed from and then back onto the primary conveyor 11, the containers 10 are transported in the direction of arrow 17 to a beverage filling station (not shown) of a conventional type.
In addition to the rotary platform 15, the secondary conveyor 12 incorporates an upper rotary platform 18 which carries three pumping systems 19. Each pumping system incorporates a peristaltic pump which is driven to deliver periodic doses in a predetermined amount of bacteria/excipient formulation through four delivery lines The delivery lines 20 are coupled to respective injectors 21 which, in use, are activated to inject the predetermined amount of the bacteria/excipient formulation into the containers 10 during the time that the containers are conveyed in the circular path around the carousel 12.
J:\Speci\300 399\300 349\34296.doc 11/05/99 A control panel 22 is provided for exercising electrical/electronic control over the apparatus in conjunction with further control systems (not shown) associated with the container feeding system.
A similar type of apparatus may be used when delivering tablet-form bacteria/excipient formulations into beverage containers. However, in such a case the apparatus will provide for the deposition of a single (preformed) tablet into each container whilst the containers are being transported around the secondary conveyor 12. For this purpose, a vibratory bowl feeder (not shown) may be mounted upon the upper rotary platform 18 of the apparatus and be arranged to feed individual tablets serially to each of a plurality of tablet releasing heads (not shown) located around the rotary platform of the secondary conveyor.
J:\Speci\300 399\300 349\34296.doc 11/05/99

Claims (14)

  1. 2. The method as claimed in claim 1 wherein the formulated mixture containing the probiotic bacteria and the excipient is delivered to each container in a liquid form.
  2. 3. The method as claimed in claim 1 wherein the formulated mixture containing the probiotic bacteria and the excipient is delivered to each container in a tablet form.
  3. 4. The method as claimed in any one of claims 1 to 3 wherein the beverage is injected into each container after delivery of the formulated mixture to the container. The method as claimed in any one of claims 1 to 4 wherein the beverage comprises milk.
  4. 6. The method as claimed in any one of claims 1 to 4 wherein the beverage comprises a fruit juice.
  5. 7. The method as claimed in any one of claims 1 to 6 wherein the mixture is formulated from a probiotic bacteria selected from a group comprising lactobacilli and bifidobacteria.
  6. 8. The method as claimed in any one of claims 1 to 7 J:\Speci\300 399\300 349\34296.doc 11/05/99 wherein the mixture is formulated from a probiotic bacteria comprising lactobacilli acidophi-llus, bifidobacteria bifidus and/or bifidobacteria infantis.
  7. 9. The method as claimed in any one of claims 1 to 8 wherein the mixture is formulated to include a blend of the probiotic bacteria and a prebiotic substance. The method as claimed in claim 9 wherein the prebiotic substance comprises a prebiotic soluble dietary fibre selected for promoting growth of the probiotic bacteria in the human gastro-intestinal tract.
  8. 11. The method as claimed in claim 10 wherein the prebiotic substance comprises an oligosaccharide.
  9. 12. The method as claimed in claim 5 wherein the mixture is formulated with the excipient composed of milk, an oligosaccharide, lactose and/or maltodextrin.
  10. 13. The method as claimed in claim 6 wherein the mixture is formulated with the excipient composed of a fruit juice and/or an oligosaccharide.
  11. 14. The method as claimed in any one of claims 1 to 13 wherein injection of the beverage into the containers is effected whilst the containers are located on a primary conveyor system and wherein the formulated mixture is delivered to the containers whilst the containers are positioned in a secondary conveyor system that is driven to divert the containers away from and back to the primary conveyor system prior to injection of the beverage into the containers. The method as claimed in claim 14 when dependent on claim 2 wherein the formulated mixture is delivered to respective ones of the containers by way of feed lines and injectors that are integrated in the secondary conveyor system.
  12. 16. The method as claimed in claim 14 when dependent on claim 3 wherein the formulated mixture is delivered to respective ones of the conveyors by way of a vibratory feeder and tablet releasing heads that are integrated in the secondary conveyor system. J:\Speci\300 399\300 349\34296.doc 11/05/99
  13. 17. The method of adding a probiotic bacteria to a beverage substantially as hereinbefore described with reference to the accompanying examples.
  14. 18. The method of adding a probiotic bacteria to a beverage substantially as hereinbefore described with reference to the accompanying drawings. J:\Speci\300 399\300 349\34296.doc 11/05/99
AU28098/99A 1997-03-18 1999-05-12 Dosing beverage with a bacteria formulation Abandoned AU2809899A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU28098/99A AU2809899A (en) 1997-03-18 1999-05-12 Dosing beverage with a bacteria formulation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPO5689 1997-03-18
AU59357/98A AU5935798A (en) 1997-03-18 1998-03-18 Pasteurised liquid dairy milk with both prebiotic and probiotic properties and procedure for manufacturing thereof
AU28098/99A AU2809899A (en) 1997-03-18 1999-05-12 Dosing beverage with a bacteria formulation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU59357/98A Division AU5935798A (en) 1997-03-18 1998-03-18 Pasteurised liquid dairy milk with both prebiotic and probiotic properties and procedure for manufacturing thereof

Publications (1)

Publication Number Publication Date
AU2809899A true AU2809899A (en) 1999-07-22

Family

ID=25620522

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28098/99A Abandoned AU2809899A (en) 1997-03-18 1999-05-12 Dosing beverage with a bacteria formulation

Country Status (1)

Country Link
AU (1) AU2809899A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US7906112B2 (en) 2003-12-19 2011-03-15 The Procter & Gamble Company Canine probiotic Lactobacilli
US7998473B2 (en) 2003-12-19 2011-08-16 The Procter & Gamble Company Methods of treatment or prevention of gastrointestinal disorders using canine probiotic bifidobacterium
US8034601B2 (en) 2005-05-31 2011-10-11 The Procter & Gamble Company Feline probiotic bifidobacteria
US8809035B2 (en) 2003-12-19 2014-08-19 The Iams Company Canine probiotic Bifidobacterium
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US9192177B2 (en) 2005-05-31 2015-11-24 The Iams Company Feline probiotic Lactobacilli
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8894991B2 (en) 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US8900569B2 (en) 2003-12-19 2014-12-02 The Iams Company Method of treating diarrhea in a canine
US7998473B2 (en) 2003-12-19 2011-08-16 The Procter & Gamble Company Methods of treatment or prevention of gastrointestinal disorders using canine probiotic bifidobacterium
US9821015B2 (en) 2003-12-19 2017-11-21 Mars, Incorporated Methods of use of probiotic bifidobacteria for companion animals
US8802158B2 (en) 2003-12-19 2014-08-12 The Iams Company Methods of use of probiotic Lactobacilli for companion animals
US8809035B2 (en) 2003-12-19 2014-08-19 The Iams Company Canine probiotic Bifidobacterium
US7906112B2 (en) 2003-12-19 2011-03-15 The Procter & Gamble Company Canine probiotic Lactobacilli
US8840880B2 (en) 2003-12-19 2014-09-23 The Iams Company Canine probiotic bifidobacteria globosum
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US8900568B2 (en) 2003-12-19 2014-12-02 The Iams Company Method of treating diarrhea in a canine
US9192177B2 (en) 2005-05-31 2015-11-24 The Iams Company Feline probiotic Lactobacilli
US8034601B2 (en) 2005-05-31 2011-10-11 The Procter & Gamble Company Feline probiotic bifidobacteria
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US10709156B2 (en) 2008-07-07 2020-07-14 Mars, Incorporated Pet supplement and methods of making
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance

Similar Documents

Publication Publication Date Title
JP5421774B2 (en) Apparatus and method for packaging beverages
CN1046404C (en) A refrigerated product containing pieces of chocolate and a process and an arrangement for its production
AU2809899A (en) Dosing beverage with a bacteria formulation
RU2006118703A (en) METHOD AND DEVICE FOR DOSED BOTTLING OF MULTILAYERED BY EXTERNAL TYPE OF DRINKS FROM LIQUID CONCENTRATES
AU2005295023A1 (en) Carbonated protein drink and method of making
CN102266107A (en) Composite prebiotics beverage and preparation method thereof
CN101502288B (en) Method for producing milk beverage with added garden stuff fiber
CN109430382A (en) It is a kind of to have effects that adjust the formula food and preparation method thereof of blood glucose
US6447823B1 (en) Liquid yogurt with encapsulated lactic acid bacteria and method for producing the same
CN101990940B (en) Fermented milk product and preparation method thereof
JP2019081733A5 (en)
KR20010039427A (en) Functional food containing yoghurt insoluble fiber for treating constipation
US8993639B2 (en) Compound and method for treatment of gastroesophageal reflux
WO2018012578A1 (en) Ghrelin secretion promotor
CN108850156A (en) A kind of probiotics solid beverage and preparation method thereof
EP2537793B1 (en) New filling method and apparatus therefore
US20200283225A1 (en) Apparatus, System and Method for Providing Enhanced Consumable Food Stuffs
CZ38719U1 (en) A composition of inoculation probiotic cultures for the controlled fermentation of food, pharmaceutical or veterinary products
US20210060137A1 (en) Nutrient compositions having enhanced bioavailability
EP0932394B1 (en) Vitamin product
CZ36968U1 (en) Composition of inoculum probiotic cultures for fermenting food, pharmaceutical or veterinary products
KR20170087984A (en) Pear beverge from lactobacillus and process for preparation thereof
CN102239974B (en) Suckling piglet growth promotion milk and preparation method thereof
Trujillo et al. Transition feeding
CN120753308A (en) Formula of yoghurt powder and whey protein powder composition

Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period